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GenScript Anuncia Exposição Itinerante Junto com a Open Monoclonal Technology, Inc.
Date:1/22/2013

os naturalmente otimizados). A OMT criou o OmniRat™, a primeira plataforma de anticorpos monoclonais totalmente humanos baseada em ratos transgênicos. O OmniRat™ usa uma melhor compreensão do desenvolvimento da célula B e uma nova abordagem para a inativação da expressão dos anticorpos endógenos, o que permite que eles façam anticorpos com idiotipos humanos de maneira tão eficiente como os ratos de tipo selvagem fazem anticorpos normais. O OmniRat™ representa uma tecnologia nova e de propriedade com opções de desenvolvimento irrestrito para anticorpos monoclonais totalmente humanos, disponíveis no mundo inteiro para todos os objetivos e indicações. A OMT também desenvolve um camundongo transgênico, o OmniMouse™, para complementar OmniRat™ e aumentar ainda mais a cobertura dos epitopos no desenvolvimento de anticorpos humanos. O OmniAb™ integra um screening profundo de anticorpos em plataformas de animais transgênicos da OMT, a comprovada imunização mediada de proteínas e DNA e o Gel-Encapsulated Microenvironment (Microambiente de Gel Encapsulado, GEM) para permitir uma geração e identificação rápida e de custo eficiente dos candidatos preferenciais a anticorpos humanos terapêuticos.

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FONTE GenScript USA Inc.


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