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Gen-Probe and DiagnoCure Amend Collaboration Agreement Surrounding PCA3-Based Prostate Cancer Tests
Date:4/29/2009

an effort to maximize the global reach for the PCA3 prostate cancer test, DiagnoCure and Gen-Probe have agreed on terms to develop key distributor relationships in countries where it is commercially more effective to do so, such as in Japan, Asia, Israel, South Africa and others.

In a separate press release today, Gen-Probe announced that it intends to initiate in the third quarter of 2009 a pivotal clinical study of its investigational PCA3 assay that could lead to regulatory approval by the U.S. Food and Drug Administration (FDA).

About PCA3

PCA3 is a molecular marker that studies indicate is more specific for prostate cancer than the commonly used diagnostic test, PSA (prostate specific antigen). PCA3 has been the subject of approximately 17 peer-reviewed publications over the past few years. A PCA3-based test, PROGENSA(R) PCA3, is now commercialized by Gen-Probe in Europe under the CE mark. In the United States, the test is not yet approved for commercialization by the FDA.

About Gen-Probe

Gen-Probe Incorporated is a global leader in the development, manufacture and marketing of rapid, accurate and cost-effective nucleic acid tests (NATs) that are used primarily to diagnose human diseases and screen donated human blood. Gen-Probe has more than 25 years of NAT expertise, and received the 2004 National Medal of Technology, America's highest honor for technological innovation, for developing NAT assays for blood screening. Gen-Probe is headquartered in San Diego and employs approximately 1,200 people. For more information, go to www.gen-probe.com.

About DiagnoCure

DiagnoCure (TSX: CUR) is a life sciences company commercializing high-value cancer diagnostic tests and delivering laboratory services that increase clinician and patient confidence in making critical treatment decisions. Diag
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SOURCE Gen-Probe Incorporated
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