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Geisinger Partners With Indivumed for Personalized Medicine Initiative
Date:5/10/2013

eat care in order to quickly translate new scientific discoveries into the practice of medicine.

Based in Hamburg, Germany, Indivumed is an integrated oncology company that leverages its biorepository of human tissue samples with its diagnostic laboratory to develop individualized cancer therapies. While Indivumed is focused on tissue testing, its subsidiary Inostics is analyzing circulating tumor DNA in plasma to determine therapy relevant cancer mutations and to monitor disease. The overall goal is understanding the biological differences between tumors and how patients respond to treatments to support the implementation of personalized therapy. To this end, Indivumed maintains a biobank of tissues and annotated data from about 17,000 patients - with about 1,500 new cases added per year - each collected under exactly defined specifications.

Research demonstrates that proteins change expression profiles significantly within minutes following surgical resection. Many of those proteins might serve as biomarkers for new drugs. Therefore, controlled and rapid tissue processing is necessary for understanding biological differences of or within patient tumors, especially when developing targeted therapies. Indivumed follows highly standardized processes that enable the company to limit cold ischemia time - the time between removal of tissue from the body and the time it is preserved - to less than 10 minutes, guaranteeing tissue samples maintain their biological integrity.

"The goal of this collaboration is to translate genetic and proteomic data into specific knowledge about a disease that is clinically relevant and will enhance patient care," Dr. Steele said. "We continually strive to look for innovative opportunities to provide patients with the most advanced care modern science has to offer."

About Geisinger Health System

Geisinger Health System is an integrated health services organization widely recognize
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