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Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte
Date:9/2/2014

ofactor(en) van een patiënt voor beroerte te bepalen; deze factoren zijn niet beperkt tot die die zijn opgenomen in vastgestelde risicoscores. De patiënten worden geïncludeerd ongeacht of zij antistollingsbehandeling ondergaan, dus kunnen huidige en toekomstige behandelingsstrategieën en falen van behandeling op de juiste wijze worden begrepen in relatie tot het individuele risicoprofiel van de patiënten.

De GARFIELD-AF-Registry wordt gefinancierd door een onbeperkte onderzoeksbeurs van Bayer Pharma AG.

De belasting van AF  

Tot 2% van de wereldbevolking heeft AF.[1] Rond de 6 miljoen mensen in Europa[8], 3-5 miljoen mensen in de Verenigde Staten[9],[10] en tot 8 miljoen mensen in China hebben AF.[11],[12] Geschat wordt dat de prevalentie van AF door het ouder worden van de bevolking in 2050 minimaal zal zijn verdubbeld. AF leidt tot een vijfvoudige stijging van het risico op beroerte en één op de vijf van alle beroertes wordt toegeschreven aan deze aritmie. Ischemische beroerte in associatie met AF is vaak fataal en die patiënten die overleven zijn daarna vaker en ernstiger gehandicapt en hebben een hoger risico op het opnieuw optreden van een beroerte dan patiënten bij wie hun beroerte een andere oorzaak heeft. Daardoor wordt het risico op overlijden als gevolg van een AF-gerelateerde beroerte verdubbeld en zijn de zorgkosten met 50% verhoogd.[13]

AF treedt op wanneer delen van de atria ongecoördineerde elektrische signalen afgeven die veroorzaken dat de kamers te snel en onregelmatig pompen, waardoor het bloed niet geheel kan worden uitgepompt.[14] Als gevolg daarvan kan bloed poolen, stollen en kan trombose optreden, wat zowel in de ontwikkelde als in de ontwikkelingslanden doodsoorzaak n
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