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Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte
Date:9/2/2014

0% een antistollingsmiddel (32,4% kreeg een VKA en 7,6% kreeg een NOAC).
  • De gegevens bevestigden ook dat deze laagrisicopatiënten vaak minder slechte klinische uitkomsten hadden, waaronder een aanzienlijk lager risico op overlijden door elke oorzaak, vergeleken met patiënten met CHA2DS2-VASc ≥ 1. Dit ondersteunde de aanbeveling in de richtlijn tegen de behandeling van laagrisicopatiënten met antistollingsbehandeling.
  • Het is waarschijnlijker dat oudere patiënten antistollingsbehandeling krijgen[7]  

    • Bij de GARFIELD-AF-patiënten werd stijgende leeftijd geassocieerd met frequenter gebruik van orale antistollingsmiddelen, een grotere incidentie van comorbiditeiten en een hoger risico op beroerte/systemisch embolisme, overlijden en ernstige bloedingen.
    • Bij patiënten van 65 jaar of ouder was cardiovasculair overlijden niet de primaire oorzaak van mortaliteit.

    Over GARFIELD-AF  

    De GARFIELD-AF Registry is een onafhankelijk initiatief op het gebied van academisch onderzoek. Het register is een observatie-, multicenter, internationaal prospectief onderzoek van patiënten met recent gediagnosticeerd AF. Het zal prospectief 500.000 patiënten volgen uit minimaal 1.000 centra in 35 landen in Noord- en Zuid-Amerika, Oost- en West-Europa, Azië, Afrika en Australië.

    Het huidige inzicht in AF is gebaseerd op gegevens verzameld in gecontroleerde klinische onderzoeken. Terwijl het essentieel is voor de beoordeling van de werkzaamheid en veiligheid van nieuwe behandelingen, zijn deze onderzoeken niet representatief voor de dagelijkse klinische praktijk en daardoor blijft de onzekerheid bestaan over de belasting in het dagelijks leven en over het onder controle houden van deze ziekte. Het doel van GARFIELD-AF is om inzichten te v
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    SOURCE GARFIELD-AF
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