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Gegevens over één jaar van wereldwijd register voor atriumfibrillatie (AF) tonen dat antitrombosemiddelen niet optimaal worden gebruikt ter voorkoming van beroertes
Date:9/3/2013

tests met betrekking tot het beroerterisico in AF-patiënten. Het onderzoek suggereert dat er mogelijkheden zijn om de uitkomsten voor patiënten te verbeteren middels een meer consistente toepassing van de beste praktijk en het gebruikmaken van de vele innovatieve therapieën ter voorkoming van beroerte in AF-patiënten met een hoog risico".

De gegevens die zijn gepresenteerd op het ESC Congress 2013, komen van de eerste van vijf GARFIELD-cohorten. Het eerste cohort omvat in totaal 10.614 patiënten met non-valvulaire AF en minstens één via onderzoek vastgestelde extra risicofactor voor een beroerte, gerekruteerd uit 540 willekeurig geselecteerde locaties in 19 landen. Van deze patiënten werden er 5.089 retrospectief gerekruteerd als een validatiecohort en werden er 5.525 prospectief gerekruteerd en zij vormen de studiepopulaties in deze abstracten. De ESC-richtlijnen voor de behandeling van atriumfibrillatie raden aan om alle patiënten met een hoog risico op een beroerte anticoagulatietherapie met vitamine K-antagonisten (VKA's) voor te schrijven, tenzij er een contra-indicatie is. Een hoog risico op een beroerte wordt gedefinieerd als een score >/=2 voor de CHA2DS2-VASc-risicoscore. Eerder gerapporteerde basisgegevens hebben laten zien dat in Cohort 1 82,6% van de patiënten CHA2DS2-VASc >/=2 had, maar dat niet meer dan 62% van deze patiënten een anticoagulatietherapie kreeg.

Gegevens van het stratificatieonderzoek naar het risico op een beroerte die zijn gepresenteerd op het ESC Congress 2013, waren beschikbaar voor 5.523 patiënten die prospectief zijn ingeschreven tussen december 2009 en oktober 2011. 

De gegevens over één jaar – die voorlopig zijn en met de nodige voorzichtigheid dienen te worden geïnterpreteerd – waren opgenomen in één mondelinge presentatie en zeven abstracten in postervorm. De mondelinge presentatie wa
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SOURCE Thrombosis Research Institute
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