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GeNO LLC Initiates Study of Inhaled NITROSYL™ Nitric Oxide in Idiopathic Pulmonary Fibrosis (PH-IPF) and Pulmonary Arterial Hypertension (PAH) Patients
Date:3/22/2011

0 patient Pilot Study to obtain preliminary safety and feasibility data from short term (15 minute) administration of inhaled nitric oxide via the GeNO Nitrosyl delivery system.  Additional study details can be found on http://clinicaltrials.gov/ ClinicalTrials.gov Identifier: NCT01092559.

"This trial has provided important information regarding preliminary safety and feasibility data from short term (15 minute) administration of inhaled NITROSYL™ nitric oxide," said Fine. "We are pleased with the performance of the system and to date, no adverse events (AEs), or unanticipated adverse device effects (UADE's) have been reported."

With the diagnostic trial ongoing, today's Phase 2 PHiano study will help GeNO establish the optimal dose for further product development (including the ambulatory system), and helps GeNO prepare to move from a diagnostic to a treatment setting.

ABOUT GeNO LLC GeNO LLC, founded in 2006, is a privately held, advanced development-stage technology company that is developing innovative nitric oxide (NO) generation and delivery platforms to enable the broad potential of inhaled nitric oxide to be realized. The company is focused on applying the new technology to deliver inhaled nitric oxide to patients in a wide variety of settings, including ambulatory and in-home use for potential chronic treatment. GeNO's NITROSYL™ Systems will be regulated by the FDA as new drugs with their own NDAs. GeNO plans to submit an IND to FDA later this year to begin evaluation of the GeNO Ambulatory NITROSYL™ System. The company has five US patents with additional patent applications pending. Media Contacts: Carla Burigatto, 610-457-2178

Brian Heffron, 781-799-9568cburigatto@gmail.com

bheffron@ctpboston.com
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SOURCE GeNO LLC
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