Navigation Links
GeNO LLC Initiates Study of Inhaled NITROSYL™ Nitric Oxide in Idiopathic Pulmonary Fibrosis (PH-IPF) and Pulmonary Arterial Hypertension (PAH) Patients
Date:3/22/2011

COCOA, Fla., March 22, 2011 /PRNewswire/ -- GeNO LLC (www.genollc.com), a privately held, advanced development-stage technology company, today announced commencement of  the PHiano Study: A Phase 2, Dose-Escalation Trial for the Treatment of Pulmonary Hypertension in patients with Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension secondary to Idiopathic Pulmonary Fibrosis (PH-IPF) using Inhaled NITROSYL™ nitric oxide (NO).  The first patient was successfully dosed at Creighton University Medical Center. This trial will be conducted at multiple clinical sites in the US, and is expected to enroll up to 75 patients.  It is designed to investigate the safety and efficacy of various doses of inhaled nitric oxide (NO), up to a maximum of 80 ppm, delivered for up to 150 minutes with GeNO's stand-alone NITROSYL™ system in subjects with WHO Group 1 PAH and WHO Group 3 PH-IPF undergoing right heart catheterization (RHC).

The primary objective of the PHiano study is to identify the minimally effective dose and the maximum effective dose (dose beyond which no further effect on pulmonary vascular resistance is seen) of inhaled NITROSYL™ nitric oxide  as compared to placebo.  Secondary objectives include assessing the safety and tolerability of inhaled nitric oxide and evaluating the pharmacokinetics of total nitrates/nitrites and methemoglobin produced following inhalation. Additional study details can be found on http://clinicaltrials.gov/ ClinicalTrials.gov Identifier: NCT01265888.  

GeNO's stand-alone gas cylinder stores premixed nitric oxide as nitrogen dioxide in either air or oxygen; however, this study will administer nitrogen dioxide only in air. The gas is allowed to flow through GeNO's proprietary cartridge containing ascorbic acid, which generates nitric oxide immediately prior to inhalation. A
'/>"/>

SOURCE GeNO LLC
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Carrington Subsidiary DelSite Initiates Critical Toxicology Studies of Its Nasal Powder Bird Flu Vaccine
2. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
3. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. MedImmune Initiates Phase 2a Multi-Dose Study in Patients with Asthma
6. Genta Initiates Phase 3 AGENDA Trial of Genasense(R) for Patients with Advanced Melanoma
7. Nuvelo Re-Initiates SONOMA-3 Trial of Alfimeprase in Patients With Catheter Occlusion
8. TorreyPines Therapeutics Initiates a Phase I Multiple Dose Clinical Trial of Tezampanel
9. Prolexys Pharmaceuticals Initiates Phase 1 Study
10. Isis Initiates Phase 1 Study of ISIS 325568 Targeting Glucagon Receptor to Treat Type 2 Diabetes
11. Lpath Demonstrates Preclinical Efficacy of Lpathomab(TM) and Initiates Humanization Process
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... CHAPEL HILL, N.C. , Jan. 23, 2015 For ... organizations are in dealing with payers. Likewise, the importance of ... payers - will only continue to grow as payer formularies ... patients access therapies. At the same time, managed ...
(Date:1/23/2015)... Partnership to Fight Chronic Disease (PFCD) released a public opinion poll ... new study analyzing the impact of increased cost sharing on patient ... to educate policy makers and the public on the costs of ... how the Iowa healthcare exchange could be ...
(Date:1/23/2015)... , Jan. 23, 2015  Immune Therapeutics, Inc. today announced the ... the compounding, packaging and distributing of its naltrexone tablets.  The ... United States . KRS Global is ... tablets in various strengths for individual patients in response to ...
Breaking Medicine Technology:As Payer Influence Rises, Pharmaceutical Companies work to Optimize the Managed Markets Function 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4
... With the support of Key Opinion Leaders clearly ... time and attention of KOLs is intensifying. But the ... for creating and maintaining KOL and physician relationships. ... landscape, Best Practices, LLC has published an updated MSL-focused ...
... 2011 CVS Caremark (NYSE: CVS ) ... President of CVS/pharmacy effective October 1, 2011.  With more ... Columbia, and Puerto Rico, CVS/pharmacy is one of the ... (Logo: http://photos.prnewswire.com/prnh/20090226/NE75914LOGO) Cosby, 52, most recently served ...
Cached Medicine Technology:Pharma Medical Science Liaison Outreach Shifting Away from Traditional Company Sales Regions 2CVS Caremark Appoints Mark S. Cosby as President of CVS/pharmacy 2CVS Caremark Appoints Mark S. Cosby as President of CVS/pharmacy 3
(Date:1/22/2015)... 22, 2015 Padre Murphy's and Owner Tom ... Pro Player Health Alliance (PPHA). The PPHA's passion ... getting everyone, including NFL greats, treated for obstructive sleep apnea ... groups supporting the cause in the valley. The most recent ...
(Date:1/22/2015)... 23, 2015 AngelWeddingDress, the premier women’s ... maternity wedding dresses. View website of AngelWeddingDress.com ... for maternity wedding dresses online for a bridal party. ... high quality for them. Its maternity wedding dresses are ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post explaining ... policy . , Auto insurance quotes help many drivers ... longer necessary to call an agent or visit an agency ... a single website: http://autocarinsurancebest.com/ . , Every business who ...
(Date:1/22/2015)... Calif. (PRWEB) January 22, 2015 ... Susan Bonilla (D-Concord) and Kristin Olsen (R-Modesto) were ... their leadership in advancing biotechnology, biomedical science, medical ... and Olsen each received the “2014 Life Sciences ...
(Date:1/22/2015)... EBSCO Information Services (EBSCO) and the American ... effort to further promote visibility and adoption of the top ... AMA journals available via its subscription services, EBSCO will now ... , Long known as both a subscription agency and ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:EBSCO Expands Partnership with the American Medical Association 2Health News:EBSCO Expands Partnership with the American Medical Association 3Health News:EBSCO Expands Partnership with the American Medical Association 4
... Corporation,(Nasdaq: AIRM ) will report financial results for ... of the market on Wednesday, March 12,2008. The Company ... at 4:15 p.m. Eastern to discuss these results., ... 396-5640,(domestic) or (706) 643-0580 (international) or by accessing the ...
... March 5 Natalie Waples,an Ottawa based and ... Board: NTNI) http://www.naturalnutritioninc.com ,subsidiary InterACTIVE Nutrition International ... Championships (height class "E") held at,the Arnolds Sports ... ), The event was held from ...
... an Antarctic fish species that adopts a winter survival ... the journal PLoS ONE, the online journal from the ... (BAS) and the University of Birmingham reveal, for the ... puts itself on ice to survive the long Antarctic ...
... Dental Network of,America Inc. (DNoA) announced today the ... The new program is now being,utilized by Health Care ... Blue Cross and Blue Shield Plans in Illinois, New ... Blue Cross and Blue Shield,Association., Research continues to ...
... March 4 Secretary of Health,Dr. Calvin B. ... workers at,Edinboro University to discuss Governor Edward G. ... hundreds of thousands of uninsured adults,through his "Cover ... is critical to help prevent disease,successfully manage chronic ...
... N.J., March 4 ,Cathedral Healthcare System Inc. has ... interest, to settle allegations that it defrauded the ... The settlement resolves allegations that the Newark, N.J.-based,hospital ... order,to obtain enhanced reimbursement from the federal health ...
Cached Medicine News:Health News:Natural Nutrition's Spokesperson and Athlete Natalie Waples Wins 2008 Arnold Amateur Figure Championship 2Health News:Hibernation-like behavior in Antarctic fish -- on ice for winter 2Health News:Dental Network of America Inc. Launches Integrated Medical-Dental Health Program 2Health News:Dental Network of America Inc. Launches Integrated Medical-Dental Health Program 3Health News:Health Secretary Stops in Erie County to Call for Health Insurance for all Pennsylvanians 2Health News:Cathedral Healthcare System to Pay U.S. $5.3 Million to Resolve Allegations Involving Inflated Charges to Obtain Higher Medicare Reimbursement 2
... The GlucoWatch G2 Biographer is intended ... glucose levels in adults (aged 18 and ... with diabetes. Parents should supervise the use ... The G2 Biographer is intended to supplement, ...
... Worlds First Solid-State Three-Color Photocoagulator.,Retinal physicians ... purchase over 3,000 Lumenis multi-color photocoagulators.,For ... practice, the Novus Varia integrates green, ... a single, compact system that supports ...
... For complete capsular protection over 360°. ... secures the eyelet positioning under the ... contact with capsule and easier implantation. ... high myopia, uveitis, diabetic, sonulo-capsular laxity, ...
... is a device designed for permanent implantation ... removal surgery. It provides secondary capsular bag ... The CTR is a uniplanar, 270-degree, semi-circle ... absorbing polymethylmethacrylate (PMMA) with one manipulation eyelet ...
Medicine Products: