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Gauze-based NPWT Capable of Achieving Same Treatment Goals as Foam-based NPWT
Date:10/24/2009

ST. PETERSBURG, Fla., Oct. 23 /PRNewswire-FirstCall/ -- The Advanced Wound Management Division of Smith & Nephew, Inc., a subsidiary of Smith & Nephew Plc (LSE: SN; NYSE: SNN), highlighted the results of a multi-center study which demonstrates that gauze-based Negative Pressure Wound Therapy (NPWT) achieves many of the common treatment goals defined for foam-based NPWT systems. These goals include a reduction in wound dimension, exudate, and improvement in granulation tissue. A second poster highlighting a sub-set of patients in the same study found that skin graft take was dramatically enhanced and care facilitated by gauze-based NPWT.

The results of this study were presented in a poster session today at the 24th Annual Clinical Symposium on Advances in Skin and Wound Care in San Antonio, Texas.

The prospective, multi-center clinical evaluation assessed 131 non-grafted patients at 21 centers in the United States, Canada, United Kingdom, Saudi Arabia and the United Arab Emirates. Its results included:

  • Wound dimensions were all significantly reduced during gauze-based NPWT (p<0.001). A weekly percentage reduction in wound area, depth and volume of 8.3%, 15.8% and 20.5% respectively was observed;
  • There was a significant reduction (p<0.001) in wound exudate levels from baseline to treatment discontinuation;
  • There was also a significant increase (p=0.007) in the percentage area of the wound bed composed of red granulation tissue over the course of gauze-based NPWT.

"Gauze-based NPWT can be used to address many of the treatment goals commonly defined at the onset of applying other NPWT systems," said Dr. Raymond Dunn, Chairman of Plastic Surgery, University of Massachusetts and lead author of the poster. "Clinicians in this study found the gauze-based negative pressu
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SOURCE Smith & Nephew Inc.
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