Navigation Links
Galenea and CHDI Foundation Announce Collaboration to Identify Key Synaptic Dysfunction in Huntington's Disease
Date:9/6/2011

ing brain and behavioral activities in parallel.  The collaboration will employ this two-pronged approach to identify and characterize the synaptic defects that occur in HD at both the neuronal and network levels.  

"We are pleased to be collaborating with CHDI who bring deep expertise and resources to the collaboration.  Our vision is to translate initial discoveries that emerge from this critical first step into novel drug candidates that positively impact the lives of Huntington's disease patients," said Mark Benjamin, DSc, Galenea's President and CEO.  David Gerber, PhD, VP of CNS Research added, "The opportunity to apply Galenea's platform to the discovery of synaptic-based therapeutics for HD is ideal.  I am confident that this collaboration will yield new insights into the underlying pathology of this disease and ultimately new therapeutic candidates."

About Huntington's disease

Huntington's disease is an inherited neurodegenerative disorder caused by a mutation in the huntingtin gene. The defect causes a DNA sequence called a CAG repeat to occur many more times than normal. Each child of a parent with a mutation in the huntingtin gene has a 50% chance of inheriting the mutation. As a result of carrying the mutation, an individual's brain cells degenerate leading to behavioral, cognitive, and motor impairments that, over the course of the disease, significantly reduce the individual's quality of life and ultimately cause death within 15 to 25 years of overt symptom onset. There are currently no therapeutics approved that slow the progression of Huntington's disease. It is estimated that the disorder affects about 30,000 people in the United States and at least 150,000 others have a 50% risk of developing Huntington's disease at some point.

About CHDI Foundation, Inc.

CHDI Foundation, Inc. is a privately-funded, not-for-profit, biomedical research organization exclusively dedica
'/>"/>

SOURCE Galenea Corp.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Galenea and Otsuka Announce Second Extension to Schizophrenia Research Collaboration
2. Kevin McHale Instrumental in Forming the Help Me Hear Foundation
3. AIDS Healthcare Foundation Names Homayoon Khanlou, M.D. as its Chief of Medicine, U.S.
4. CellCyte Genetics Corp. Enters Collaborative Research Agreement With Cleveland Clinic Foundation to Qualify Stem Cell Delivery in Damaged Heart Tissue
5. Nobel Prize Awarded to Foundation for Biomedical Research Board Member
6. The Oral Cancer Foundation Urges HPV Vaccination for Males
7. MedicAlert Foundation Joins The Alzheimers Association to Offer MedicAlert(R) + Alzheimers Association Safe Return(R) - Live 24-Hour Emergency Response for Wandering and Medical Emergencies
8. Phase 1 & 2 Data of Perifosine (KRX-0401) in Patients with Advanced Renal Cell Carcinoma Presented Today at the 25th Annual Chemotherapy Foundation Symposium
9. Grantees of the Avon Foundation Breast Cancer Prevention Research Initiative Gather in Houston to Report Interim Findings
10. Five Clinical Studies to Receive $2.5 Million Under Foundations 2007 Clinical Discovery Program
11. Alpha-1 Foundation, AARC Cooperate on Study to Test 5,000 COPD Patients for Alpha-1
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 15, 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) ... support, China,s orthopedic instrument industry ... market size rising from 3.28 billion yuan in 2006 ...
(Date:1/15/2014)... WASHINGTON , Jan. 15, 2014 AARP Foundation today ... support older adults suffering from the severe cold weather that ... are committed to helping those in need; so to support ... dollar-for-dollar contributions up to $250,000, which could mean up to ...
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ... (OFT) approval condition to the announced tender offer for all of ... As a result of the waiver, the transaction is no longer ... offer on January 24, 2014 following the currently scheduled expiration time, ...
Breaking Medicine Technology:Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3
... Holdings, Inc. (NYSE: ZMH ; SIX: ZMH) announced today its second ... Internet on Thursday, July 22, 2010 , at 8:00 a.m. Eastern ... at 7:00 a.m. the morning of the conference call. , ... The live audio webcast can be accessed via ...
... people with disabilities, their families, caregivers, seniors, veterans and healthcare professionals are expected to ... 2010 at the Schaumburg Convention Center. Admission is free and show ... am to 5 pm and Sunday 11 am to 4 pm . ... Abilities Expo has put together an impressive line-up ...
Cached Medicine Technology:Zimmer Holdings Announces Live Audio Webcast and Conference Call of Second Quarter 2010 Results 2People With Disabilities Experience Their Possibilities at Abilities Expo Chicagoland 2People With Disabilities Experience Their Possibilities at Abilities Expo Chicagoland 3
(Date:4/23/2014)... and Leisure Time Physical Activity on Mobility Limitation in ... increases the risk of mobility limitation in old age, ... found in a study which followed up 5,200 public ... at the Gerontology Research Center in Finland and the ... is often repetitive, wears the body and lasts for ...
(Date:4/23/2014)... as Ritalin, may prevent the depletion of self-control, according ... journal of the Association for Psychological Science. , Self-control ... trying to focus attention on a boring textbook are ... explanation for this difficulty: Exerting self-control for a long ... effectively on subsequent tasks. , "It is as if ...
(Date:4/23/2014)... the bottom of Alzheimer,s disease has been a ... controversies. In the latest crook in the research ... the interaction between proteins associated with the disease. ... ACS Chemical Neuroscience , could have important implications ... Krzysztof Nieznanski and colleagues explain that for years, ...
(Date:4/22/2014)... and industry leaders visited the New Jersey Institute ... Joel S. Bloom for the launch of the ... that provides a new model for business innovation ... education assets and investment. U.S. Senator Cory Booker, ... Joe Taylor, New Jersey Lieutenant Governor Kim Guadagno, ...
(Date:4/22/2014)... the last few decades researchers have characterized a set ... and behavior in all types of species, from flies ... identified, but researchers surmise there are more. A team ... of Pennsylvania wondered if big-data approaches could find them. ... by John Hogenesch, PhD, professor of Pharmacology and first ...
Breaking Medicine News(10 mins):Health News:Midlife occupational and leisure-time physical activity limits mobility in old age 2Health News:ADHD drug may help preserve our self-control resources 2Health News:Government and industry leaders herald launch of NJIT's New Jersey Innovation Institute 2Health News:Bioinformatics profiling identifies a new mammalian clock gene 2
... a Million People Nationwide to take 10 Billion, Steps ... WASHINGTON, Sept. 17 More than 1,500 YMCAs ... active living and,healthy eating during "America On the Move ... partnership with the America On the Move,Foundation, aims to ...
... Science Series to Focus on Cardiovascular Disease, Prevention and Treatment Options, ... ... NEW YORK, Sept. 17 The upcoming episode of the "Charlie,Rose ... leading,global killers, which claims almost 900,000 lives each year in the United,States ...
... A new study by researchers at the University of Southern ... , Researchers found that a storyline on the primetime ... and healthy eating habits had a positive impact on the ... study, published in the Sept. 14 Journal of Health Communication ...
... cancer in the head and neck region may have ... without the disease, according to a report in the ... one of the JAMA/Archives journals. , Driving is a ... functions that work together. These functions can be compromised ...
... the Medicare,Quality Improvement Organization for Florida, is ... Laredo, Texas to provide free Diabetes,Empowerment Education ... 33,Florida counties. According to Kathleen Lightbourne, Project ... "The Program is designed to help,people with ...
... Open House - Saturday, October 20,Event to be held ... WEST PLAINS, Mo., Sept. 17 GAMMILL QUILTING ... systems, in,cooperation with it,s nationwide network of dealers, will ... 20. This event is being,held in honor of October,s ...
Cached Medicine News:Health News:Activate America(R) Brings Together YMCAs Nationwide to Promote Small Steps Toward a Healthier Lifestyle During 'America on the Move Week With the YMCA,' September 22-29, 2007 2Health News:Activate America(R) Brings Together YMCAs Nationwide to Promote Small Steps Toward a Healthier Lifestyle During 'America on the Move Week With the YMCA,' September 22-29, 2007 3Health News:Activate America(R) Brings Together YMCAs Nationwide to Promote Small Steps Toward a Healthier Lifestyle During 'America on the Move Week With the YMCA,' September 22-29, 2007 4Health News:Activate America(R) Brings Together YMCAs Nationwide to Promote Small Steps Toward a Healthier Lifestyle During 'America on the Move Week With the YMCA,' September 22-29, 2007 5Health News:Charlie Rose Science Series Explores Heart Disease 2Health News:Charlie Rose Science Series Explores Heart Disease 3Health News:ER episode impacts viewers' health knowledge and behavior 2Health News:Patients with head and neck cancer may have impairment of some driving skills 2Health News:Medicare Every Diabetic Counts Project Gears Up for Kick-Off 2Health News:'Think Pink with Gammill(R)' 2
... Inverness Medical Professional Diagnostics is a leading ... IFA and DFA test menu that includes ... STDs as well as miscellaneous conjugates and ... you a wide assortment of substrates and ...
... Professional Diagnostics is a leading provider of ... DFA test menu that includes kits for ... well as miscellaneous conjugates and components. Our ... wide assortment of substrates and kit sizes ...
... Our breadth of infectious disease ELISA products ... With standard assay protocols for faster integration ... ELISA products provide increased reliability and run-to-run ... antibody detection assays for a wide range ...
... Our breadth of infectious disease ELISA ... field. With standard assay protocols for faster ... Disease ELISA products provide increased reliability and ... includes antibody detection assays for a wide ...
Medicine Products: