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GSK research estimates significantly higher rates of pertussis among older adults than now reported
Date:9/12/2013

ected or are misdiagnosed as other respiratory ailments," said Leonard Friedland, M.D., Vice President and Director of Scientific Affairs and Public Health for GSK Vaccines. "To our knowledge, this is the first attempt to quantify the incidence of cough illness attributed to B. pertussis via regression modeling among those greater than 50 years old. The authors plan to share their research methods and welcome other researchers to further examine and build upon the findings of this study. These findings suggest a major need for healthcare providers to consider the possibility of pertussis in older patients they see who have respiratory symptoms."  

According to the CDC, there were 48,277 cases of pertussis reported in the U.S. in 2012. This was the most cases reported in the U.S. since 1955 when nearly 63,000 cases were reported. In 2011, 18,719 cases were reported. The CDC has developed and published a comprehensive pertussis guide that can be accessed at http://www.cdc.gov/pertussis/outbreaks/about.html.

The results of this study should be interpreted in the context of its limitations. Claims data are inherently limiting, because they are collected for billing and reimbursement purposes rather than for research. Only patients seeking medical attention from private practitioners and only positive B. pertussis laboratory tests were included. Lastly, the incidence of cough attributed to B. pertussis was based on mathematical modelling. Models try to mimic the reality and are subject to numerous limitations and assumptions.

About GlaxoSmithKline Vaccines

GlaxoSmithKline Vaccines, a division of GlaxoSmithKline, is the world's leading vaccine company and a leader in innovation. The company is active in vaccine research, development and production with over 30 vaccines approved
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