Navigation Links
GSK Announces Results of First Phase III Trial Evaluating Tykerb(R) (Lapatinib) Plus Herceptin(R) (Trastuzumab)
Date:5/16/2008

revention, supportive care, chemotherapy and targeted therapies. For more information about GSK Oncology, visit http://www.gskoncology.com.

About GlaxoSmithKline

GlaxoSmithKline -- one of the world's leading research-based pharmaceutical and healthcare companies -- is committed to improving the quality of human life by enabling people to do more, feel better, and live longer. To access the latest GSK Oncology media materials, visit http://www.gsk.com/media. For more information about GSK Oncology, visit http://www.gskoncology.com.

TYKERB Important Safety Information

TYKERB has been associated with hepatotoxicity. The hepatotoxicity may be severe and deaths have been reported. Causality is uncertain. Patients should receive liver function tests before initiation of treatment, every 4 to 6 weeks during treatment, and as clinically indicated. A dose reduction in patients with severe pre-existing hepatic impairment should be considered. Discontinue and do not restart TYKERB if patients experience severe changes in liver function tests.

As with other therapies for HER2 overexpression, TYKERB has been associated with reports of decreases in left ventricular ejection fraction (LVEF). Caution should be taken if TYKERB is to be administered to patients with pre-existing cardiac conditions, including uncontrolled or symptomatic angina, arrhythmias, or congestive heart failure. LVEF should be evaluated in all patients prior to and during treatment with TYKERB.

Diarrhea was the most common adverse event resulting in discontinuation of study medication. Proactive management of diarrhea with anti-diarrheal agents is important, and severe cases of diarrhea may require administration of oral or intravenous electrolytes and fluids and interruption or discontinuation of therapy with
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. ADVENTRX Announces ANX-530 Safety Data From Registrational Bioequivalence Clinical Study
2. Medivation Announces Presentation of MDV3100 Clinical Data in Patients With Castration-Resistant Prostate Cancer at 44th American Society of Clinical Oncology Annual Meeting
3. BiPar Sciences Announces Clinical Data Presentations on Lead PARP Inhibitor, BSI-201, at 40th American Society of Clinical Oncology Annual Meeting
4. IDM Pharma Announces Updated Data From Mifamurtide (L-MTP-PE) Compassionate Access Program
5. Biopure Announces Publication of Phase II Proof-of-Concept Coronary Trial
6. Quigley Announces Successful Poultry Study of Chickens With Infectious Bronchitis; Plans to Approach the Poultry Industry for Potential Commercialization
7. Kosan Announces Data Presentations at ASCO 2008 Annual Meeting
8. XTENT Announces Positive Six-Month CUSTOM III Trial Data Presented at EuroPCR Meeting
9. NicOx Announces Initiation of First Phase 1 Study of Investigational Nitric Oxide-Donating Agent in Hypertensive Patients by Merck & Co., Inc.
10. Alseres Pharmaceuticals Announces 12 Month Interim Results from the Phase I/IIa Cethrin(R) Clinical Trial in Acute Spinal Cord Injury
11. Medarex Announces Initiation of Phase 2 Clinical Trials for the Treatment of Ulcerative Colitis and Rheumatoid Arthritis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/1/2015)... , July 1, 2015  Unilife Corporation (NASDAQ: ... supplier of injectable drug delivery systems, announced today that ... of June 30, 2015. This amendment removed a covenant ... in cash receipts from customers during the six months ... to any of the terms of the debt agreement ...
(Date:7/1/2015)... 2015  LabStyle Innovations Corp. (DRIO), developer of ... appointment of Todd Durniak as Senior Vice President and ... LabStyle over 20 years of medical device commercial ... President and General Manager of Neighborhood Diabetes, a ... through durable medical equipment (DME) and pharmacy channels ...
(Date:7/1/2015)... Boston Scientific Corporation (NYSE: BSX ) will ... for the second quarter ended June 30, 2015 on Thursday, ... call will be hosted by Mike Mahoney , president ... vice president and chief financial officer. A live ... Boston Scientific website. Webcast registration is available on the Investor ...
Breaking Medicine Technology:Unilife and OrbiMed Amend Debt Financing Agreement 2Unilife and OrbiMed Amend Debt Financing Agreement 3LabStyle Innovations Appoints Senior VP & General Manager in U.S. for the Dario Diabetes Management Solution 2LabStyle Innovations Appoints Senior VP & General Manager in U.S. for the Dario Diabetes Management Solution 3LabStyle Innovations Appoints Senior VP & General Manager in U.S. for the Dario Diabetes Management Solution 4Boston Scientific To Webcast Second Quarter 2015 Earnings Call On July 23 2
... NEW YORK, Oct. 11, 2011 PLC Medical Systems, ... RetailInvestorConferences.com presentation is available for on-demand viewing. ... "register/ watch event now" button. PLC Medical ... Investors may download shareholder materials from the "virtual trade ...
... 11, 2011 I-Flow announced today ... purchasing agreement by HealthTrust Purchasing Group, L.P. (HealthTrust), ... covers I-Flow,s flagship ON-Q® products for incisional, nerve ... PainBuster®, ON-Q® SilverSoaker™ Catheters and ON-Q® disposable and ...
Cached Medicine Technology:PLC Medical Systems CEO Presentation Now Available for On-demand Viewing at RetailInvestorConferences.com 2I-Flow LLC, a Kimberly-Clark Health Care Company Announces Agreement for ON-Q® Products With HealthTrust Purchasing Group 2
(Date:7/1/2015)... ... 2015 , ... METTLER TOLEDO is pleased to announce the ... balances give operators the room they need to carry out weighing tasks confidently. ... balances a perfect choice for day-to-day weighing in nearly any analytical or manufacturing ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... team as Director of Referral Relations. , Emily originally entered the behavioral ... she designed and implemented unique academic curriculum for clients to engage in their ...
(Date:7/1/2015)... (PRWEB) , ... July 01, 2015 , ... ... different philosophies and approaches to case management, placement, sober companionship and delivery to ... and approaches to working with and transporting clients with anxiety, ADHD, autism spectrum ...
(Date:7/1/2015)... ... July 01, 2015 , ... ... and the Florida Panhandle, the regional southeast Alabama community health system announced ... clinical communications workflow solution provider. TelmedIQ, a burgeoning leader in secure healthcare ...
(Date:7/1/2015)... ... ... Nutritional Products International, a brand focused on the global marketing and distribution ... Diet, Vitamin & Sports Nutrition conference in Tampa, Florida, where it made a number ... allows companies the chance to meet with a variety of the most influential executives ...
Breaking Medicine News(10 mins):Health News:METTLER TOLEDO Launches Compact ML-T Balances: Larger Pan Offers Greater Weighing Flexibility in Tight Spaces 2Health News:Northbound Treatment Services Welcomes Emily Orrick as Director of Referral Relations 2Health News:All Kinds of Therapy – Announces New Partnership Feature, Therapeutic Experts 2Health News:Southeast Alabama Community Health System Chooses TelmedIQ to Meet Secure Text Messaging Challenges for Healthcare 2Health News:NPI Meets With Top Retail Figures at ECRM Conference 2
... Will Earn Decision Resources, Gold Standard Status for ... Report from Decision ResourcesWALTHAM, Mass., April 29 ... and advisory firms for pharmaceutical and healthcare issues, ... on cognitive decline as the attribute that most ...
... April 29 , - ... Eye-Catching,Online Campaign , Bausch & ... solutions in its continued effort to improve the habits ... of the THINK,EYEGIENE(TM) campaign, Bausch & Lomb is introducing ...
... & Mentally IllNEW YORK, April 29 May marks ... it, philanthropic-minded New Yorkers will raise money for Weston ... and physically disabled. As federal and state funding ... the current economy, supporters will raise funds amidst live ...
... transmitted through the respiratory tract and spread when people come in contact ... ... 29, 2009 -- When it comes to the recent swine flu outbreak, ... control and Prevention (CDC) in Atlanta, agree that the first order of ...
... in a global campaign to stop drug, alcohol and substance abuse, ... prevention pamphlets that present drug facts and the danger of drugs ... ... 2009 -- Members, friends and allies of Scientologists and Church ...
... ST. PAUL, Minn., April 29 Minnesota, which has long ... the Air Report, earning mostly solid "A" and "B" grades ... to be scored, fared much more poorly in this year,s ... for ozone pollution, enacted last year.Three counties, Anoka, Mille Lacs ...
Cached Medicine News:Health News:For Alzheimer's Disease, Surveyed Neurologists Identify a Therapy's Effect on Cognitive Decline as the Attribute That Most Influences Their Prescribing Decisions 2Health News:For Alzheimer's Disease, Surveyed Neurologists Identify a Therapy's Effect on Cognitive Decline as the Attribute That Most Influences Their Prescribing Decisions 3Health News:A Clear Solution for Healthy Eyes 2Health News:A Clear Solution for Healthy Eyes 3Health News:A Clear Solution for Healthy Eyes 4Health News:Weston United Celebrates Mental Health Month on May 19th 2Health News:Swine Flu Prevention: Information & Products from Allegro Medical 2Health News:Swine Flu Prevention: Information & Products from Allegro Medical 3Health News:Church of Scientology Distributes Drug Abuse and Addiction Facts Internationally 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: