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Future Therapeutic Drug Monitoring Market: US, Europe, Japan
Date:12/7/2011

6; Vital Diagnostics ATAC 8000

° Vital Diagnostics Envoy 500

C. Major In Vitro Diagnostic Technologies

And Their Potential Applications

1. Monoclonal and Polyclonal Antibodies

2. Immunoassays

a. Technological Principle

b. Radioimmunoassays (RIA)

c. Enzyme Immunoassays (EIA)

° Overview

° ELISA

° EMIT

° Immunofiltration

° Dot Immunobinding Assays

° Capillary ImmunoassaysTable of Contents (Continued)

° Particle-Membrane Capture Immunoassays

° Enzyme Amplification

° CEDIA

° Electrochemical Immunoassays

d. Fluorescent Immunoassays

° Fluorescence Polarization

° Time-Resolved Pulse Fluorescence

e. Luminescence

° Chemiluminescence

° Bioluminescence

f. Latex Agglutination

g. Immunoprecipitation

h. Affinity Chromatography Immunoassays

i. Liposome Flow-Injection Immunoassays

3. IT and Automation

4. Dry Chemistry

5. Biosensors

6. Robotics

7. Chemometrics

8. Molecular Diagnostics

a. Sample Preparation

b. Hybridization

c. Separation

d. Detection/Measurement

Test Formats

a. Filter Hybridization

b. Southern Blot

c. Northern Blot

d. In Situ Hybridization

e. Others

Labeling Techniques

Amplification Methods

? Polymerase Chain Reaction

- Temperature Cyclers

- PCR Variations

* Immuno-PCR

* QC-PCR.

* DAP-PCR

? Strand Displacement Activation

? TMA

? Ligase Chain Reaction

? Branched DNATable of Contents (Continued)

- Hybridization Protection Assay

? Nucleic-Acid Sequence-Based Amplification

? Self-Sustained Sequence Replicase

? Others

- Ampliprobe

- CAR

- CAS

- CPT

- D
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