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Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
Date:9/22/2007

CHICAGO, Sept. 20 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (Nasdaq: ADLS), presented further data in support of cethromycin, the Company's lead compound, at the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy in Chicago, September 17 - 20. A total of seven poster presentations were made, some of which, in collaboration with Eurofins Medinet and Micromyx, discussed in vitro activity of cethromycin against key susceptible and resistant pathogens involved in community acquired pneumonia (CAP), while others reviewed safety data in certain special clinical populations. In addition, along with collaborators such as the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) and Battelle, the Company presented data demonstrating the potency of cethromycin against pathogens involved in bioterrorism.

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The following poster presentations were made regarding the safety profile of cethromycin in certain special clinical populations:

"Evaluation of the Safety and Pharmacokinetics of Cethromycin Following Administration of Single and Multiple Doses to Subjects with Mild or Moderate Chronic Hepatic Insufficiency"

Cethromycin at 300 mg once daily for seven days was well tolerated by subjects with hepatic impairment and subjects with normal hepatic function. The results suggest that no dose adjustment is required when cethromycin is administered to subjects with mild or moderate hepatic impairment.

"Evaluation of the Safety and Pharmacokinetics of Cethromycin Following Administration of Multiple Dose
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SOURCE Advanced Life Sciences Holdings, Inc.
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