Navigation Links
Further Data on Safety and Efficacy of Cethromycin Presented at 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
Date:9/21/2007

rrently available drugs.

"Assessment of In Vitro Activity of Cethromycin Against Strains of Haemophilus Influenzae"

Cethromycin demonstrated potent in vitro activity against all Haemophius influenzae isolates studied regardless of beta-lactamase status. Based on the MIC data, cethromycin potency was comparable to telithromycin and azithromycin, and was superior to clarithromycin. These findings demonstrate that cethromycin has the potential to be a potent therapeutic option for the treatment of CAP caused by Haemophilus influenzae.

The following poster presentations demonstrated the potency of cethromycin as a potential treatment against bioterrorism pathogens:

"Efficacy of Cethromycin Against a Lethal Inhalation Anthrax Challenge in Rhesus Macaques"

All antibiotic treated animals maintained normal hematologic parameters and remained abacteremic throughout the treatment period. All cethromycin- treated animals survived, with only 1/10 demonstrating abnormal hematologic parameters following antibiotic cessation. One ciprofloxacin-treated animal demonstrated clinical signs of infection, bacteremia, alterations in hematologic and coagulation parameters, and died nine days after cessation of antibiotic treatments. All 10 control monkeys demonstrated a combination of clinical signs of anthrax, bacteremia, and/or alterations in hematologic and coagulation parameters post-challenge with five of ten succumbing to the infection. This study demonstrated that a thirty day course of oral cethromycin was 100% protective against a lethal dose of inhaled Bacillus anthracis Ames strain spores.

"Antimicrobial Activity of Cethromycin, a Novel Ketolide, Tested Against a Diverse Collection of Francisella Tularensis Strains"

Cethromycin was efficacious against 30 Francisella tularensis strains. Cethromycin had significant in vitro activity against Francisella tularensis. Cethromycin preferentially accumulates in the alveolar cells of the lungs,
'/>"/>

SOURCE Advanced Life Sciences Holdings, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
2. Molecular Target of Bradmers Neuradiab Further Validated by Independent Findings
3. Phase III Clinical Trial with 4-Month Long-Acting Formulation of Triptorelin: Ipsen Decides Not to Perform Further Administration
4. Further Statistical Analysis of the Recent Phase III trial on Lead Product M6G Shows Additional Benefits
5. New Data on Market-Leading Velcade (Bortezomib) for Injection Further Strengthen Role in Previously Treated Multiple Myeloma
6. Liponex Inc. Reports Further Analysis of CRD5 Phase I/II Clinical Trial Data
7. MIV Therapeutics Announces Pivotal Test Results Further Validating Company Stent Coatings Meet Critical FDA Fatigue Guidelines
8. Managing Preanalytical Processes for Patient Safety
9. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
10. New Phase 3 Study Published in The Lancet Evaluates Efficacy and Safety of Prezista/Ritonavir vs. Kaletra as Part of HIV Combination Therapy in Treatment-Experienced Adults With HIV
11. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... May 22, 2015 Research and Markets ... of the "Latest Regulations on Pharmaceutical International ... their offering. This is first time ... guidance on international multi-center clinical trials of drugs ... begun to be implemented on March 1, 2015. ...
(Date:5/22/2015)... May 22, 2015 Richmond ... research unit with a worldwide reputation for excellence ... frequent publications in peer reviewed medical journals. Its ... and regulators in discussions about rules for transparency ...      (Logo: http://photos.prnewswire.com/prnh/20150522/745125) , Clinical research ...
(Date:5/21/2015)... , May 21, 2015 ... has announced the addition of the ... (Ankle Replacement, Digit Replacement, Elbow Replacement, Hip ... to 2019" report to their offering. ... knee replacement was valued at $4,470.9 million ...
Breaking Medicine Technology:2015 Regulations on Pharmaceutical International Multi-Center Clinical Trials in China 2North American Joint Reconstruction Market 2015-2019 - Zimmer Holdings, DePuy Synthes Companies, Stryker, Biomet & Smith & Nephew Dominates the $4.4 Billion Market 2
... 2012  Tris Pharma, a technology driven specialty pharmaceutical ... Drug Administration (FDA) has approved the first-ever generic ... dextromethorphan polistirex. Delsym was approved ... generic alternative approved until now. Tris has pioneered ...
... CBI has released their interactive agenda for Access World, ... the annual congresses on Rare Disease, Access Programs for ... Access for shared networking and tailored content. ... regulators during FDA addresses , Case studies from ...
Cached Medicine Technology:Tris Pharma Announces Approval of First-Ever Generic to Delsym® Dextromethorphan Polistirex Extended-Release Suspension 2
(Date:5/22/2015)... Power Systems is proud to announce the sponsorship of ... is in his second year of racing in the professional ... Fire Department in Missoula, MT. He entered the triathlon scene ... career, he has had 15 1st Place finishes. In his ... in all seven of his 2014 races, including two 2nd ...
(Date:5/22/2015)... 22, 2015 According to Berks and ... drug related death, totaling almost 2,500 confirmed drug deaths, as ... state officials, totals 2,489 deaths stemming from legal and illegal ... loses seven people every day to fatal overdoses or other ... out as one of the most rife with drug related ...
(Date:5/22/2015)... York, NY (PRWEB) May 22, 2015 Medivo, ... entitled “Positivity Rates and Genotype Results in ‘Baby Boomers’ ... Results from a Nationwide Lab Test Database” at Digestive Disease ... by Medivo’s Clinical Affairs and Analytics team members Carol Smyth, ... MD; and Andrea Parker, MSI, along with Nancy Reau, MD ...
(Date:5/22/2015)... Wimbledon Health Partners, the leading on-site ... and NCV testing , is proud to announce ... American National athlete, to the Wimbledon Athletics division. ... level of testing and information it provides to be ... trainers, this way they can focus on the task ...
(Date:5/22/2015)... In an effort to support the athletes ... to donate $5 dollars for every maintenance call, and ... softening system. Customers have their needs serviced, and donations ... and the Special Olympics receives money. Hence the name ... 4.4 million athletes, and boasts a myriad of events. ...
Breaking Medicine News(10 mins):Health News:Philadelphia Ranks Among the Tops Cities in Penn. for Drug Deaths 2Health News:Medivo Study Finds HCV Positivity Rates are 250% Higher Among Baby Boomers 2Health News:Wimbledon Athletics Recruits Team USA Athlete 2Health News:Wimbledon Athletics Recruits Team USA Athlete 3Health News:Parker and Sons is Proud to Support the Special Olympics with Their Everybody Wins Program 2
... findings from the nation,s largest study of diabetes in ... rise among every racial and ethnic group studied. Five ... Care provide a comprehensive picture of diabetes in ... in the United States, including non-Hispanic whites, Hispanics, blacks, ...
... Health Specialists physicians will provide 50 free colonoscopies to patients impacted ... ... (PRWEB) February 27, 2009 -- On Saturday, March 14, the physicians ... to perform 50 free screening colonoscopies to help those in our ...
... Board of Directors of Schering-Plough Corporation (NYSE: SGP ... common share. Payment will be made on May 26, ... on May 1, 2009. As of Jan. 31, 2009, ... today also declared a quarterly dividend of $3.75 per share ...
... looks forward to working with Obama AdministrationWASHINGTON, Feb. 27 ... learn that budget documents released by the White House ... of hospitals owned and operated by reform-minded physicians."We understand ... past CBO data. We look forward to the opportunity ...
... Georgia study suggests that health agencies investigating Salmonella illnesses ... of contamination. , Researchers, whose results appear in the ... Microbiology , tested water over a one-year period in ... known for its high rate of sporadic salmonella cases. ...
... - Probiotics expert Dr. Mary Ellen Sanders and food ... with insightful tips for retailers -TORRANCE, Calif., Feb. 27 ... probiotic products have been introduced to the U.S. marketplace. ... well-informed about what differentiates probiotic products from others is ...
Cached Medicine News:Health News:Many faces of diabetes in American youth: The SEARCH for diabetes in youth study 2Health News:Many faces of diabetes in American youth: The SEARCH for diabetes in youth study 3Health News:Many faces of diabetes in American youth: The SEARCH for diabetes in youth study 4Health News:Local Gastroenterology Practice Gives Back to the Community During Colon Cancer Awareness Month 2Health News:Physician's Hospitals Are a Model of True Health Care Reform 2Health News:Physician's Hospitals Are a Model of True Health Care Reform 3Health News:Physician's Hospitals Are a Model of True Health Care Reform 4Health News:Physician's Hospitals Are a Model of True Health Care Reform 5Health News:Physician's Hospitals Are a Model of True Health Care Reform 6Health News:Physician's Hospitals Are a Model of True Health Care Reform 7Health News:Physician's Hospitals Are a Model of True Health Care Reform 8Health News:Physician's Hospitals Are a Model of True Health Care Reform 9Health News:Physician's Hospitals Are a Model of True Health Care Reform 10Health News:Study suggests surface water contaminated with salmonella more common than thought 2Health News:Study suggests surface water contaminated with salmonella more common than thought 3Health News:Retailers, Buyers to Learn how to Navigate Probiotic Marketplace at Natural Products Expo West 2009 2
Maddox Rod, short handle (12cm)...
Graham Field 10' Reversed Snellen Eye Chart....
... PacScan 300AP is a portable, ... provides easy-to-use touch screen operation. ... frequency, low noise probes and ... capture immediately upon application of ...
Precision that fits in the palm of your hand and measures down to 125 microns, the Pocket Pachymeter is about 8" X 4" x 2" and really does fit in a lab coat pocket or briefcase....
Medicine Products: