Navigation Links
Further Analysis From ATHENA Study Showed That Multaq(R) (dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation
Date:9/3/2008

versity, Department of Cardiology, Hamilton Canada, co-principal investigator of the ATHENA study.

The most frequently reported adverse events of Multaq(R) vs. placebo in the ATHENA trial as seen in the pre-specified safety analysis, were gastrointestinal effects (26% vs. 22%), skin disorders (10% vs. 8%, mainly rash) and mild increase in blood creatinine (4.7% vs. 1%). The mechanism of blood creatinine increase was well defined in a separate study of healthy volunteers. In the ATHENA trial, compared to placebo, Multaq(R) showed a low risk of pro-arrhythmia and no excess of hospitalisations for congestive heart failure. There was a similar rate of study drug discontinuation between the 2 study groups.

About Atrial Fibrillation / Flutter and Stroke

Atrial Fibrillation (AF) is the most common cardiac arrhythmia in clinical practice and is one of the most important independent risk factors for stroke. Stroke is a major public health problem because this acute event often causes permanent neurological disabilities and death. Atrial fibrillation increases the risk of stroke by up to 5 times. It also is responsible for 15-20% of all strokes, which if caused by AF, are 2.2 times more likely to leave patients bedridden.

Atrial fibrillation is a major cause of hospitalization and mortality and affects about 2.5 million people in the USA and 4.5 million people in the European Union. The Atrial Fibrillation Foundation expects the number of patients with AF to double in the next 20 years. Without appropriate management, atrial fibrillation can lead to serious complications, such as stroke and congestive heart failure.

About the ATHENA Study

The landmark ATHENA, study is the only double-blind, anti-arrhythmic, morbidity-mortality study in patients with atrial fibrillation. It was conducted in more than 550 sites in 37 countries and enrolled a total of 4,628 patients.

The patients studied in ATHENA were either 75 years of age or ol
'/>"/>

SOURCE sanofi-aventis
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Further Analysis From ATHENA Study Showed That Multaq(R)(Dronedarone) Reduced the Risk of Stroke in Patients With Atrial Fibrillation
2. Intercell Announces Initiation of Further Phase II Clinical Trial of V710 an Investigational Vaccine to Prevent S. aureus Infection
3. Addrenex Pharmaceuticals New Hires Further Company Goal to Identify New Drugs for Adrenergic Regulation
4. Blood Pressure Lowering Effect of Hypertension Treatment Device Further Validated in New Studies
5. Published Guidelines Further Support Use of Bioimpedance Measurement Technology for Early Assessment of Lymphedema
6. Further Clinical Testing of BZL101 in Advanced Breast Cancer Demonstrates Favorable Efficacy and Toxicity Profiles
7. QuatRx Pharmaceuticals Announces Presentation of Further Data from Ophena(TM) (Ospemifene) Phase 3 Study for Treatment of Symptoms of Vulvovaginal Atrophy
8. New Roche Data to be Presented at ASCO Offers Further Hope for Cancer Patients
9. Roche Exercises its Option to Further Develop and Commercialize Memory Pharmaceuticals Nicotinic Alpha-7 Agonist, MEM 3454
10. GlaxoSmithKline Reports Further Progress of Oncology Portfolio
11. Arpida Provides Further Comments on the Pivotal Phase III Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... privately held medical device company, announced today that it ... Corporation (Tokyo Stock Exchange TYO: 8001) to sell its ... in Japan . ViewRay,s technology, the ... MRI-guided radiation therapy system that images and treats cancer ...
(Date:1/22/2015)... THOUSAND OAKS, Calif. , Jan. 22, 2015  Amgen (NASDAQ: ... quarter and full year 2014 financial results on Tuesday, Jan. 27, ... will be followed by a conference call with the investment community ... be Robert A. Bradway , chairman and chief executive officer, ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... of the "Microbiology Testing/Clinical Microbiology Market by ... Forecast to 2019" report to their offering. ... array of techniques for the detection of infectious ...
Breaking Medicine Technology:ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Amgen Announces Webcast of 2014 Fourth Quarter and Full Year Financial Results 2Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 2Global Microbiology Testing/Clinical Microbiology (Instrument, Analyzer, Incubator, Kit, Microscope, Molecular Diagnostics) Market - Forecast to 2019 3
... PHILADELPHIA, Dec. 16, 2010 Premier Research Group ... company, announces the appointment of Christopher Codeanne to ... Mr. Codeanne has more than 20 years ... Prior to joining Premier Research, he was the ...
... Novo Nordisk, a world leader in diabetes care, has partnered ... Ganassi Racing team for 2011 IZOD IndyCar season. ... by American racecar driver Charlie Kimball. This partnership makes Kimball one ... to move up the official "Road to Indy" with a full ...
Cached Medicine Technology:Christopher Codeanne Appointed Chief Financial Officer of Premier Research Group 2Novo Nordisk and Chip Ganassi Racing Team Up for 2011 IZOD IndyCar Series 2Novo Nordisk and Chip Ganassi Racing Team Up for 2011 IZOD IndyCar Series 3Novo Nordisk and Chip Ganassi Racing Team Up for 2011 IZOD IndyCar Series 4Novo Nordisk and Chip Ganassi Racing Team Up for 2011 IZOD IndyCar Series 5Novo Nordisk and Chip Ganassi Racing Team Up for 2011 IZOD IndyCar Series 6
(Date:1/22/2015)... Glendale, AZ (PRWEB) January 22, 2015 Padre ... a long supporter of Pro Player Health Alliance ... with Padre Murphy's in getting everyone, including NFL greats, treated ... one of the leading groups supporting the cause in the ...
(Date:1/22/2015)... The Incredible Bulk is a revolutionary method put together ... by up to 30lbs in less than 12 weeks without ... Stevenson, prompting an investigative review. , “Our Incredible Bulk ... formula that allows the body to pack on a massive ...
(Date:1/22/2015)... Blue Cross and Blue Shield of Minnesota (Blue Cross) ... to “Live Fearless.” , The “Faces of Fearless” ... about how they or someone they know has faced a ... the moment. By telling these types of stories through livefearlessmn.com, ...
(Date:1/22/2015)... 22, 2015 The federal court overseeing thousands ... District Court, Southern District of West Virginia has upheld a ... proceeding’s first bellwether trial. In an Order dated January 21st, ... after finding that C.R. Bard had not proven a miscarriage ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 A new ... of experience and person-centeredness in the long-term care environment ... action across the continuum. The paper, “The Power of ... engages perspectives and practices of the patient, resident and ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3
... at The University of Nottingham say our stress levels at work ... and decrease as we head towards retirement. In the ... to be carried out in Britain researchers from the Institute of ... in our working lives can stay with us well into retirement. ...
... than 3 years may be at increased risk, researchers say , ... a while, but don,t let your child use one too long, ... 3 to 5 in Patagonia, Chile, researchers found that children who ... years were three times as likely as other kids to develop ...
... Steaz, the nation,s premier brand of organic and ... -- the first certified organic, all-natural zero calorie carbonated ... Zero Calorie is a delicious, all-natural alternative for diet ... ingredients and sweetened with the all-natural leaves of the ...
... 21 Lake Health, formerly Lake Hospital System, today ... TriPoint Medical Center in Concord Township. A state-of-the-art digital ... experience for patients, families and the community. , ... Built from the ground up to enhance healing and ...
... ... to announce that it has made another significant commitment to environmental sustainability by joining ... are engaged in reducing their environmental footprints. , ... Irvine, CA (PRWEB) October 21, 2009 -- Vestara, provider ...
... ... woes, budgets are tightening, banks aren,t lending and consumers aren,t spending. ... and businesses are cringing at the sound of customers slamming shut ... downturn, and still others are continuing to experience rapid growth. Among ...
Cached Medicine News:Health News:Older workers are the healthy 'survivors' of the workplace 2Health News:Steaz Launches Organic, Zero Calorie Sparkling Line 2Health News:Lake Health Celebrates Grand Opening of TriPoint Medical Center 2Health News:Lake Health Celebrates Grand Opening of TriPoint Medical Center 3Health News:Lake Health Celebrates Grand Opening of TriPoint Medical Center 4Health News:Lake Health Celebrates Grand Opening of TriPoint Medical Center 5Health News:Lake Health Celebrates Grand Opening of TriPoint Medical Center 6Health News:Lake Health Celebrates Grand Opening of TriPoint Medical Center 7Health News:Vestara Joins National Health Organization Practice Greenhealth to Further Support Environmental Practices 2Health News:Vestara Joins National Health Organization Practice Greenhealth to Further Support Environmental Practices 3Health News:Apple Vending is a Strong Growth Segment Despite Tough Economic Times 2Health News:Apple Vending is a Strong Growth Segment Despite Tough Economic Times 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: