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Frost & Sullivan Applauds Check-Cap for Pioneering a Non-invasive, Prep-Free Wireless Capsule Endoscope

MOUNTAIN VIEW, Calif., Nov. 11, 2013 /PRNewswire/ -- Based on its recent analysis of the wireless capsule endoscopes market, Frost & Sullivan recognizes Check-Cap Ltd. with the 2013 European Frost & Sullivan Award for New Product Innovation Leadership.

Check-Cap's capsule device, also named Check-Cap, is based on a novel imaging approach that enables the 3D virtual reconstruction of the colon, eliminating the need for bowel preparation. The imaging capsule, which resembles a vitamin capsule in its size and shape, is easy to swallow and is designed to wirelessly transmit data to a small receiver that is no bigger than a disposable patch on the patient back.

Wireless capsules need to satisfy the requirement of the two key stakeholders in the market the patients and the physicians. From the perspective of the patient, the capsule has to do away with, or at least significantly ease the most bothersome aspect of the current screening procedure, namely, bowel preparation. They also have to be small enough for easy oral administration and unhindered mobility through the gastrointestinal track. From the physician's perspective, it should provide 360-degree visualization and cover the colon comprehensively in both quality and quantity. Check-Cap checks both these boxes and is peerless in its efficiency.

"While competing products strive for a 360-degree view of the colon by adopting multiple cameras and either fall short or risk image overlaps and redundancy, Check-Cap has adopted an X-ray platform that not only enables a 360-degree view, but also obtains information that is 'hidden' or inaccessible to other products that employ rays of visible light," said Frost & Sullivan Research Analyst Bhargav Rajan.

Although wireless capsule endoscopes are more comfortable than traditional endoscopes for the patient, they suffer from incomplete imaging of the colon due to lack of maneuverability. To combine the best of both wireless and traditional endoscopes, Check-Cap uses X-ray Radar technology, which emits X-rays through the device's surface in all directions. The X-ray data that is backscattered and captured by the capsule detectors, is then converted, post-procedure, to 3D images of the colon's internal surfaces. X-rays, unlike light rays, can pass through solid content and tissues. This feature allows physicians to perform the procedure without an uncomfortable and prolonged colon cleansing procedure and detect polyps that are not visible to other capsule endoscopes.

Check-Cap is currently undergoing clinical trials in Europe and is planning to submit the request to initiate an efficacy study in North America late next year. Like other routine radiographic diagnosis of the gastrointestinal tract, Check-Cap requires a barium-swallow pre-procedure to help differentiate the colon structure from the content.

The X-Radar technology also maximizes the critical diagnostic time available to the physician, while the 3D reconstruction of the colon facilitates accurate diagnosis. Check-Cap not only eliminates the redundancy caused by multiple cameras, but also ensures that there is little or no chance of images being left out or not captured through insufficient coverage.

"Check-Cap estimates a review time of 7 to 10 minutes to be sufficient for physicians to identify clinically significant polyps and prescribe a follow-up accordingly," noted Rajan. "X-ray Radar technology not only differentiates the Check-Cap product from its competitors, but is also designed to match classical colonoscopy in its clinical accuracy."

Each year, Frost & Sullivan presents this award to the company that has developed an innovative element in a product by leveraging leading-edge technologies. The award recognizes the value added features/benefits of the product and the increased ROI it offers customers, which, in turn, increases customer acquisition and overall market penetration potential.

Frost & Sullivan Best Practices Awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service, and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis, and extensive secondary research in order to identify best practices in the industry.

About Check-Cap Ltd.

Check-Cap is a clinical-stage medical device company focused on the development of gastrointestinal imaging devices. Check-Cap is developing a proprietary screening methodology that combines the safety of pill endoscopy and the resolution of optical methodologies while eliminating the need for aggressive preparation of the patient bowel prior to screening.

Check-Cap believes its technology represents a breakthrough in providing an effective structural exam without the pain, discomfort and embarrassment experienced by patients undergoing traditional colonoscopy and other currently available capsule endoscopy.

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.

Our "Growth Partnership" supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.

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Mireya Espinoza
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Guy Neev
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SOURCE Frost & Sullivan
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