Navigation Links
Frost & Sullivan: TNF Inhibitors Lay the Groundwork for the Next Generation of Disease-Modifying Anti-Rheumatic Drugs

MOUNTAIN VIEW, Calif., Dec. 5, 2012 /PRNewswire/ -- The challenges inherent in the pharmacological management of rheumatic diseases have stoked huge demand for drug classes with excellent safety and efficacy profiles. While tumor necrosis factor (TNF) inhibitors have greatly enhanced the treatment of these incurable chronic conditions, their unpredictable and inconsistent efficacy as well as their high cost, potential side effects, and uncomfortable mode of delivery (by injection) are driving the need for alternative therapies.

New analysis from Frost & Sullivan's ( The United States Rheumatic Diseases Therapeutics Market research finds that rheumatic disease therapeutics prescribed as add-on therapies to background standard therapies earned revenues of approximately $8.99 billion in 2011 and estimates this to reach $14.04 billion by 2017.  Frost & Sullivan has also analyzed sub-segments of the U.S. rheumatic diseases therapeutics market, including psoriatic arthritis, ankylosing spondylitis, and rheumatoid arthritis pharmacotherapeutics.

If you are interested in more information on this research, please send an email to Britni Myers, Corporate Communications, at, with your full name, company name, job title, telephone number, company email address, company website, city, state and country.

Although TNF inhibitors have improved the lives of millions of rheumatic disease patients, there is still a vast, underserved patient pool that does not respond to this class of drugs. This huge market potential is driving pharmaceutical and biotechnology companies with immunology and inflammatory disease expertise to develop affordable alternatives with better efficacy.

"TNF inhibitors are currently the only add-on treatment option for psoriatic arthritis and ankylosing spondylitis patients, many of whom do not respond to this class and have no alternatives," said Frost & Sullivan Senior Industry Analyst Deborah Toscano. "New agents hope to offer patient-friendly alternatives to TNF inhibitors with additional benefits such as oral administration or better tolerability, with the ultimate goal of improving long-term clinical outcomes."

While no area of pharmacotherapeutics is without need of improvement, the unmet needs for rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis have significantly decreased with the availability of TNF inhibitors. Thus, the main challenge for new entrants is the entrenchment of TNF inhibitors within the medical and regulatory communities.

"To gain acceptance from regulatory authorities, clinicians, and patients, emerging therapies must demonstrate economic benefits and a higher degree of safety over TNF inhibitors," noted Toscano. "Companies must also effectively market the safety and efficacy profiles as well as the robust clinical history of their drugs to raise awareness and gain the confidence of prescribing rheumatologists, patients and payors."

The United States Rheumatic Diseases Therapeutics Market is part of the Life Sciences Growth Partnership Services program, which also includes research in the following markets: U.S. Market for Ankylosing Spondylitis Pharmacotherapy, U.S. Market for Psoriatic Arthritis Pharmacotherapy, U.S. Rheumatoid Arthritis Market: Assessment of Biologics and New Treatments, Rheumatoid Arthritis Therapeutics Market in Australia, and Rheumatoid Arthritis Therapeutics Market in India. All research services included in subscriptions provide detailed market opportunities and industry trends evaluated following extensive interviews with market participants.

About Frost & Sullivan

Frost & Sullivan, the Growth Partnership Company, works in collaboration with clients to leverage visionary innovation that addresses the global challenges and related growth opportunities that will make or break today's market participants.

Our "Growth Partnership" supports clients by addressing these opportunities and incorporating two key elements driving visionary innovation: The Integrated Value Proposition and The Partnership Infrastructure.

  • The Integrated Value Proposition provides support to our clients throughout all phases of their journey to visionary innovation including: research, analysis, strategy, vision, innovation and implementation.
  • The Partnership Infrastructure is entirely unique as it constructs the foundation upon which visionary innovation becomes possible. This includes our 360 degree research, comprehensive industry coverage, career best practices as well as our global footprint of more than 40 offices.

For more than 50 years, we have been developing growth strategies for the global 1000, emerging businesses, the public sector and the investment community. Is your organization prepared for the next profound wave of industry convergence, disruptive technologies, increasing competitive intensity, Mega Trends, breakthrough best practices, changing customer dynamics and emerging economies?

Contact Us:     Start the discussion

Join Us:           Join our community

Subscribe:       Newsletter on "the next big thing"

Register:         Gain access to visionary innovation

The United States Rheumatic Diseases Therapeutics Market

Britni Myers
Corporate Communications – North America
P: 210.477.8481
F: 210.348.1003

SOURCE Frost & Sullivan
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Private Healthcare Facilities Strengthen Cardiac Patient Monitoring Devices Market in CEE, Finds Frost & Sullivan
2. Double-digit Growth Rate of the Pharmaceuticals Industry in Asia Pacific Boosts the API Market, Finds Frost & Sullivan
3. High Degree of Disease Prevalence Sustains Diabetes Diagnostics Market in Europe, Finds Frost & Sullivan
4. Frost & Sullivan: Investments in Healthcare Improvements to Bolster the Integration of Picture Archiving and Communications Systems in Latin America
5. Frost & Sullivan: U.S. Health Information Exchange Market Enters Prime Time in Rapidly Transforming Healthcare Industry
6. Frost & Sullivan Honors Acuo Technologies with 2012 Market Share Leadership Award in Enterprise Imaging Informatics
7. Government Investments in Upgrades Sustain Laboratory Analytical Instrumentation Market in China, Finds Frost & Sullivan
8. Skin Integrity Products (SIP): Effective Distribution Networks Are Key to Penetrating Western European Market, Says Frost & Sullivan
9. Frost & Sullivan: Respirator Manufacturers to Develop Innovative Solutions to Overcome Economic Challenges in North America
10. Innovative Drugs to Transform European Alzheimers Disease Medication Market by 2015, Says Frost & Sullivan
11. Frost & Sullivan: Lack of Proper Price Regulation for Pharmaceuticals
Post Your Comments:
(Date:11/25/2015)... , Nov. 26, 2015  The total global healthcare industry ... over 2015-2016. Latin America has the ... , (excluding Japan ), is second with ... continues to face increased healthcare expenditure. In 2013-2014, total government ... from 43.5% in 2008-2009 to 41.2% in 2013-2014. In real ...
(Date:11/25/2015)... 25, 2015 AAIPharma Services Corp./Cambridge Major ... at least $15.8  Million to expand its laboratories ... . The expansion will provide additional office ... growing demands of the pharmaceutical and biotechnology markets. ... will provide up to 40,000 square feet of ...
(Date:11/25/2015)... November 25, 2015 Kitov Pharma ... (TASE: KTOV), a biopharmaceutical company focused on the development ... clinical conditions, today announced the closing of its previously ... ( ADSs ), each representing 20 ordinary shares of ... ADSs. The ADSs and warrants were issued in a ...
Breaking Medicine Technology:
(Date:11/25/2015)... Cleveland, OH (PRWEB) , ... November 25, 2015 , ... ... dental implants in Cleveland, OH , are invited to attend Dr. Mark Iacobelli’s Advanced ... 5th this year in Cleveland, OH. , As the co-founders of Advanced Implant ...
(Date:11/25/2015)... (PRWEB) , ... November 25, 2015 , ... The McHenry ... a recent successful appellate decision obtained by Attorneys Francisco J. Botto and Alex C. ... v. Illinois Workers’ Compensation Comm’n, 2015 IL App (2d) 130884WC. , According to court ...
(Date:11/25/2015)... ... November 25, 2015 , ... SCOTTSDALE, AZ) - ... surgeon specializing in both surgical and non-surgical treatments, announced the expansion of his ... Facial Plastic Surgery. , Highly trained and nationally recognized for his natural ...
(Date:11/25/2015)... ... ... In an ongoing Clinical Study conducted by an independent physician, Andrew Gostine, ... evaluating the efficacy of its product and its disinfection protocol. This study is taking ... 2014 through October 2015 at a 360-bed, acute-care, academic medical center located in Chicago, ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... provide scholarships for people struggling with eating disorders as a result of the ... second annual event, held at Fox Run Golf Club in Eureka, will help ...
Breaking Medicine News(10 mins):