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Frost & Sullivan: Label-Free Technology is a High Potential Market with Myriad Unexplored Applications
Date:7/3/2012

LONDON, July 3, 2012 /PRNewswire/ -- The inherent advantages of label-free technology is a significant factor in driving its adoption.  The promise of reducing drug failure caused by toxicity is another key factor likely to boost the uptake of label-free technology.

New analysis from Frost & Sullivan (http://www.drugdiscovery.frost.com), Western European Market for Label Free Detection (LFD) Systems, finds that the market earned revenues of $60.9 million in 2010 and estimates this to reach $160.9 million in 2017 at a compound annual growth rate (CAGR) of 14.9 per cent from 2010-2017. The research covers key segments including biochemical assays and cell-based assays.

"The key advantage of label-free technologies is that it is true to its word: it is "label-free" as it requires no labelling or reporter molecules," notes Frost & Sullivan Programme Manager Ranjith Gopinathan. "Labels are known for their altering effect on molecules under study which, in turn, alters its binding or physicochemical properties."

The absence of labels also means lesser interference from compound autofluorescence and colour quenching, therefore leading to fewer false positives and negatives. It is also devoid of problems arising from secondary detection of auxiliary reagents.

"By virtue of its direct detection capabilities, label-free technologies could enable the use of natural ligands and substrates that is currently not possible with label-based detection assays," adds Gopinathan. "Avoidance of radioactive labels is an attractive factor for label-free technologies as this means better lab safety and cost savings from evasion of radioactive waste disposable procedures."

Of the many reasons for escalating clinical development costs, drug failure caused by toxicity is a chronic and growing problem in drug development. The problem of toxicity holds the promise of being s
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SOURCE Frost & Sullivan
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