Freezing Prostate Cancer Does a Man's... (atients 112 (93 percent) had no evidence...)

Freezing Prostate Cancer Does a Man's Body Good

Date:3/9/2009

atients, 112 (93 percent) had no evidence of cancer -- in spite of 72 being labeled medium to high risk for cancer recurrence. "There were no local recurrences in the areas we treated, and with the ability to re-treat the 7 percent of patients who developed a focus of cancer at a different site in the gland; cryoablation was 100 percent effective in local control of the patient's disease," said Onik. He reported that 85 percent of the men retained sexual function. Of those who did not have previous prostate surgery, all remained continent. "Incontinence becomes a big issue with many patients. For some it's a more important side effect than impotence," said Onik.

According to Onik, the 3-D transperineal biopsy complements the focal cryoablation approach because earlier detection of smaller tumors increases the likelihood that a small tumor can be treated using cryoablation. In his study, Onik restaged 180 patients who had previously undergone TRUS mapping biopsies who were considering conservative management for their cancer. The results showed that 70 percent of the men would have their management changed by the new information provided by mapping. Through mapping, more than 50 percent of men who were diagnosed with cancer on one side of the prostate gland with traditional TRUS biopsy had undetected cancer on the other side as well, he said. Management of prostate cancer is in great part determined by the Gleason score, a cancer ranking method indicating tumor grade and stage and the extent and location of a patient's disease. "When we restaged the men, we found that 22 percent of them experienced an increase in their Gleason score -- meaning that they had a more aggressive cancer than was originally thought from their original biopsy. The 3-D mapping biopsy provided life-saving information," said Onik. "This biopsy technique allows us to map the location of the tumor with tremendous precision and has the potential to greatly affect the decis
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SOURCE Society of Interventional Radiology
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