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Four Studies Published in The Lancet Show roflumilast (Daxas(R)), a New Oral Approach to COPD, Improves Lung Function and Reduces Exacerbations
Date:8/27/2009

a hospital. Exacerbations are frightening events resulting in increased patient anxiety, worsening health status, lung function decline and increased risk of death.

Smoking is a major contributory factor in western countries, and pollution from fires for cooking and heating is an additional contributory factor in less developed countries. Industrial and chemical pollutants can also cause COPD.

Chronic inflammation in the lungs plays a significant role in COPD. Current medications used to treat the condition deal mainly with symptoms rather than the underlying disease. Roflumilast is a new PDE4 inhibitor being developed specifically to target the chronic inflammation which is COPD-related.

About Nycomed

Nycomed is a privately owned global pharmaceutical company with a differentiated portfolio focused on branded medicines in gastroenterology, respiratory and inflammatory diseases, pain, osteoporosis and tissue management. An extensive range of OTC products completes the portfolio.

Its R&D is structured around partnerships and in-licensing is a cornerstone of the company's growth strategy.

Nycomed employs 12,000 associates worldwide, and its products are available in more than 100 countries. It has strong platforms in Europe and in fast-growing markets such as Russia/CIS and Latin America. While the US and Japan are commercialised through best-in-class partners, Nycomed plans to further strengthen its own position in key Asian markets.

Headquartered in Zurich, Switzerland, the company generated total sales of euro 3.4 billion in 2008 and an adjusted EBITDA of euro 1.2 billion.

For more information visit www.nycomed.com

About Forest Laboratories

Forest Laboratories (NYSE: FRX) is
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SOURCE Nycomed
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