Navigation Links
Four Alzheimer's Clinical Trials Address a Variety of Treatment Targets - Amyloid, Tau, Synapse Formation
Date:7/29/2008

- Unsuccessful Phase III Study Does Not Mean the End of Anti-Amyloid Therapies -

CHICAGO, July 29 /PRNewswire-USNewswire/ -- Results from four studies of potential new treatments for Alzheimer's - even an unsuccessful late stage clinical trial - increase the field's knowledge and point scientists toward advances in therapies for the disease, according to research reported today at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease (ICAD 2008), in Chicago.

The reports included data from:

-- A Phase III trial of tarenflurbil (Flurizan, Myriad), an anti-amyloid therapy, that failed to achieve its primary endpoints.

-- A 12-week, Phase IIa trial of PBT2 (Prana Biotechnology), which reduces the toxic form of amyloid by preventing the interaction of amyloid with copper and zinc in the brain.

-- A 84-week, Phase II trial of methylthioninium chloride (rember(TM), TauRx Therapeutics), a tau aggregation inhibitor that targets toxic tau aggregates, or "tangles." Tangles of tau in the brain are another characteristic hallmark of Alzheimer's.

-- A proof of concept clinical trial in mild Alzheimer's of Souvenaid (Danone Research-Centre for Specialised Nutrition), a "medical food" product that encourages the formation of brain synapses and may reduce beta amyloid.

"While researchers continue to investigate amyloid as a target for Alzheimer's therapies - it is the most mature theory being pursued - we must also examine other potential avenues given the urgency of conquering this disease," said Samuel Gandy, MD, Ph.D., chair of the Alzheimer's Association's Medical and Scientific Advisory Council. "We can't leave any stone unturned if we hope to aid the 5 million people currently living with Alzheimer's and the millions more that will be devastated by this epidemic."

While currently approved treatment options for Alzheimer's offer some relief of symptoms for perhaps a year or two, they do no
'/>"/>

SOURCE Alzheimer's Association
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11

Related medicine technology :

1. Echo Therapeutics Announces Positive Results of a Clinical Study of its Symphony(TM) Transdermal Continuous Glucose Monitoring System in Patients with Type 1 and Type 2 Diabetes
2. CuraGen Reports Second Quarter 2008 Financial Results and Clinical Progress of CR011-vcMMAE
3. Cadence Pharmaceuticals to Host Conference Call and Webcast to Discuss Second Quarter 2008 Financial Results and Provide a Clinical Program Update on August 7, 2008
4. Emisphere Presents Dramatic Clinical Evidence Demonstrating New Approach to Vitamin B12 Supplementation
5. Controversy About Lack of Placebo Group Decline in Alzheimers Clinical Trials
6. Genaera Releases Phase 1 Data and New Preclinical Data on the CNS Function of Trodusquemine (MSI-1436) at CBI Obesity Summit
7. Journal of Clinical Oncology Article Highlights CellSearch(TM) Circulating Tumor Cell Test in Treatment of Metastatic Colorectal Cancer
8. Alexza Initiates Second Phase 3 Clinical Trial for AZ-004 (Staccato(R) Loxapine)
9. Pharmatech, Inc. Contracts for Five New Just-in-Time Clinical Trials
10. Jennerex Publishes Clinical Trial Data With Lead Product JX-594 Demonstrating Efficacy Against Liver Cancer and Associated Hepatitis B Virus
11. Hyperion Therapeutics Completes Enrollment in Phase 1/2 Clinical Trial in Patients With Urea Cycle Disorders
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... 2015 Magnaquest, a leading ... and cloud computing operators has signed a Proof ... for Internet of Things (IoT) related initiative. The ... subscription model.      (Logo: http://photos.prnewswire.com/prnh/20140807/700645 ... for business innovations to make healthcare services more ...
(Date:7/30/2015)... July 30, 2015  ResMed (NYSE: ... a definitive agreement to acquire Curative Medical, ... and sleep-disordered breathing medical devices and accessories. ... in China, combined with ResMed,s global leadership in sleep and respiratory ... China suffering from sleep-disordered ...
(Date:7/30/2015)... DIEGO , July 30, 2015  Tandem ... medical device company and manufacturer of the t:slim® ... has entered into non-exclusive Development Agreements with Dexcom, ... Tandem insulin pumps with the Dexcom G5 and ... "Integrating Tandem,s next generation pump platform with Dexcom,s ...
Breaking Medicine Technology:Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 2ResMed Invests in High-Growth Chinese Sleep and Respiratory Care Market with Curative Medical 3Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 2Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 3
... an Interventional Radiology Treatment -- Detailed for Those ... Osteoplasty -- a highly effective minimally invasive procedure ... disease by injecting bone cement to support weakened ... often presenting individuals who are suffering terribly with ...
... Any Age: Comparison by Interventional Radiologists Shows No ... FistulasSAN DIEGO, March 9 A new study ... disease, it doesn,t matter if you,re young or ... for maintaining access to one,s circulatory system to ...
Cached Medicine Technology:Metastatic Bone Disease Patients Can Walk in Lazarus' Footsteps 2Metastatic Bone Disease Patients Can Walk in Lazarus' Footsteps 3Metastatic Bone Disease Patients Can Walk in Lazarus' Footsteps 4Metastatic Bone Disease Patients Can Walk in Lazarus' Footsteps 5For Old or Young Dialysis Patients, AV Fistulas Remain Pure Gold 2For Old or Young Dialysis Patients, AV Fistulas Remain Pure Gold 3For Old or Young Dialysis Patients, AV Fistulas Remain Pure Gold 4
(Date:7/31/2015)... St. Louis, MO (PRWEB) , ... July 31, 2015 , ... ... litigation* currently underway in U.S. District Court in the Northern District of Illinois, Androgel ... documents. On Monday, July 20, a docket entry was made recording the minutes of ...
(Date:7/31/2015)... ... July 31, 2015 , ... People ... when purchasing disability insurance, where price is an important factor to clients when ... leading insurance carrier, offers the Preferred Producer Multi-Life Discount program, where advisers pass ...
(Date:7/30/2015)... VA (PRWEB) , ... July 31, 2015 , ... ... Floor:, Reduce Errors By 50% or More, **Presented by FDAnews and Ginette M. ... Ginette Collazo, a 15 year veteran of helping drug, biologic and device firms ...
(Date:7/30/2015)... Sierra Madre, CA (PRWEB) , ... July 30, 2015 , ... ... wound care programs, the activity of recruiting patients becomes a serious challenge. Because of ... wound care program to patients within the local community. , The team at ...
(Date:7/30/2015)... , ... July 30, 2015 , ... ... program entitled " Lovetraction Lines ." It's for women interested in improving their ... they desire. The course, which officially launched to the public early this morning, ...
Breaking Medicine News(10 mins):Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 2Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 3Health News:Testosterone Lawsuit News: Androgel Lawsuit Conference Held 4Health News:Secura Consultants Gives Advisers Competitive New Edge with Multi-Life Discount Program 2Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 2Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 3Health News:FDAnews Announces — Reduce Human Error on the Drug and Device Manufacturing Floor: Reduce Errors By 50% or More Workshop, Sept. 16-17, 2015 4Health News:WCA Offers Shockwave; The Marketing Module for Hospital Wound Care Programs 2Health News:WCA Offers Shockwave; The Marketing Module for Hospital Wound Care Programs 3Health News:WCA Offers Shockwave; The Marketing Module for Hospital Wound Care Programs 4Health News:Lovetraction Lines - Review Examining Simone Myers' New Online Course Released 2
... ... bomb is to explode in the coming years , ... London, UK (PRWEB) June 13, 2009 -- New images released by Lloydspharmacy show how ... affects around a quarter of the UK population, one of the highest prevalence rates for hayfever ...
... Calif., June 12 An independent factfinder jointly hired by Fresno ... County,s plan to cut the wages and benefits of 10,000 home ... and ordered that the cuts be halted. The Fresno Board of ... Tuesday. , , SEIU UHW invoked their right to arbitration ...
... Customs Enforcement Slow to Act, Not Doing Enough to Protect Employees, ... and Customs Enforcement Krome Service Processing Center in Miami, FL has ... has urged the agency for weeks to fit its personnel with ... with the H1N1 virus. "This is an outrage that it ...
... Ill., June 12 The American College of Chest ... historic 79-17 vote yesterday and the U.S. House of ... Food and Drug Administration meaningful authority to regulate tobacco ... represents the strongest legislation Congress has ever passed to ...
... says , FRIDAY, June 12 (HealthDay News) -- Here,s more ... about 4 percent of males develop dry eye disease, making ... for seeing an eye doctor in the United States, researchers ... or burning sensation in the eyes, according to the North ...
... ... largest online retailer of vision care products, unveils the newest addition to its collection ... organic, recycled material making them an environmentally friendly choice. , ... Vancouver, BC (PRWEB) - Clearly Contacts, the ...
Cached Medicine News:Health News:Lloydspharmacy Reveals Hayfever Misery to Hit One in Two People by 2060 2Health News:Lloydspharmacy Reveals Hayfever Misery to Hit One in Two People by 2060 3Health News:Neutral Factfinder Rules That Fresno County Home Care Wage Cuts Should Be Stopped 2Health News:Krome Immigration Service Processing Center Has Confirmed H1N1 Flu Cases 2Health News:American College of Chest Physicians Celebrates the Nation's Victory for Tobacco Control 2Health News:For Men Over 50, Odds of Eye Discomfort Increases 2Health News:Clearly Contacts Goes Green With Organic Glasses 2
Inquire...
Power Supply E865 is ideal for electrophoresis and semi-dry blotting applications. The electrical leads from Hoefer Gel apparatus are fully compatible with this new E865 power supply and there is no ...
Inquire...
... Scientific PSE Power Supply . The digital ... V and 2 A in 1 volt and ... run up to three SEA 2000® apparatus simultaneously ... preset and actual values of voltage, current and ...
Medicine Products: