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Foundation Venture Capital Group Invests in Start-Up Company Developing Blood Test to Determine Risk and Diagnose Alzheimer's Disease
Date:5/14/2010

," explained George F. Heinrich, M.D., vice chair and CEO of Foundation Venture Capital Group.  "His success could help ease the suffering of millions of people worldwide as they struggle with this devastating disease."

Dr. Nagele explained that brain-reactive autoantibodies and amyloid beta peptides are abundant in the blood but are unable to cross the blood brain barrier in healthy individuals.  His research now shows that these autoantibodies and peptides can readily penetrate through defects in the barrier that result from degenerative conditions common to vascular systems of older individuals.  

"We found that once these autoantibodies and peptides leak into brain tissue, they selectively bind to neurons in the brain that are most affected by Alzheimer's - cells that are critical to memory and higher thinking," he said. "Our hope is that these results will spark development of new therapies aimed at lowering blood levels of these peptides which could slow progression or circumvent this devastating illness."

Foundation Venture Capital Group, an affiliate of New Jersey Health Foundation, was founded in 2006 to invest only in commercially viable new start-up companies developing technology at UMDNJ. Since that time it has invested in four other UMDNJ companies including Actinobac Biomed Inc., developing a therapeutic agent targeting blood cells for the treatment of hematological malignancies; CellXplore, Inc., engaged in the development of biomarker-based in vitro diagnostic assays for cancer; Longevica Pharmaceuticals, Inc. developing a chemoprotective agent that may keep normal cells healthy during cancer treatments; and Snowdon Pharmaceuticals, a drug discovery company focused on several major therapeutic areas.

For more information, contact James Golubieski,
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SOURCE Foundation Venture Capital Group, LLC
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