Navigation Links
Foundation Venture Capital Group Invests in Start-Up Company Developing Blood Test to Determine Risk and Diagnose Alzheimer's Disease
Date:5/14/2010

NEW BRUNSWICK, N.J., May 14 /PRNewswire-USNewswire/ -- As many as 5.3 million Americans, and 35 million people worldwide, are living with Alzheimer's disease (AD), a devastating neurodegenerative illness characterized by memory loss, cognitive decline and widespread destruction of neurons in the brain.  Today, there is no definitive diagnosis for the disease, and no treatment to cure it.

AD is the most common form of dementia and, with our aging population, the number of people who will develop the disease is expected to increase dramatically in the future.  

With Foundation Venture Capital Group, LLC's, latest investment, James M. Golubieski, president, is hoping to help to lower those numbers dramatically.  That's why the company has made an initial investment of $175,000, which can go up to $500,000 pending completion of certain milestones, to Durin Technologies, Inc., a start-up company developing a test that requires only a drop of blood to diagnose the disease.

"My research centers on the fact that autoantibodies are involved in the degenerative mechanism of AD," explained Robert Nagele, PhD, founder of Durin Technologies and a researcher at the Institute for Successful Aging at the UMDNJ-School of Osteopathic Medicine in Stratford, NJ.

Dr. Nagele noted that the concept is gaining support in the scientific community and a number of pharmaceutical companies are seriously looking into it to help diagnose, and later treat, AD.

"We are hopeful that Dr. Nagele's research will help to fill an unmet need in the diagnostic and pharmaceutical industries," explained George F. Heinrich, M.D., vice chair and CEO of Foundation Venture Capital Group.  "His success could help ease the suffering of millions of people worldwide as they struggle with this devastating disease."

Dr. Nagele explained that brain-reactive autoantibodies and amyloid beta peptides are abundant in the blood but are unable to cross the blood brain barrier in healthy individuals.  His research now shows that these autoantibodies and peptides can readily penetrate through defects in the barrier that result from degenerative conditions common to vascular systems of older individuals.  

"We found that once these autoantibodies and peptides leak into brain tissue, they selectively bind to neurons in the brain that are most affected by Alzheimer's - cells that are critical to memory and higher thinking," he said. "Our hope is that these results will spark development of new therapies aimed at lowering blood levels of these peptides which could slow progression or circumvent this devastating illness."

Foundation Venture Capital Group, an affiliate of New Jersey Health Foundation, was founded in 2006 to invest only in commercially viable new start-up companies developing technology at UMDNJ. Since that time it has invested in four other UMDNJ companies including Actinobac Biomed Inc., developing a therapeutic agent targeting blood cells for the treatment of hematological malignancies; CellXplore, Inc., engaged in the development of biomarker-based in vitro diagnostic assays for cancer; Longevica Pharmaceuticals, Inc. developing a chemoprotective agent that may keep normal cells healthy during cancer treatments; and Snowdon Pharmaceuticals, a drug discovery company focused on several major therapeutic areas.

For more information, contact James Golubieski, president of Foundation Venture Capital Group, at

(908) 731-6601 or at jgolubieski@njhf.org.


'/>"/>
SOURCE Foundation Venture Capital Group, LLC
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. The Arkansas Hospital Auxiliary Association and the MedicAlert Foundation Partner to Offer Emergency Medical Information and Identification Services for Arkansans
2. The Gift of Hearing Will be Delivered Free to Over 75 Beneficiaries, as Speedway Childrens Charities and the Starkey Hearing Foundation Host Get in Gear to Help Children Hear
3. Alzheimers Drug Discovery Foundation Funds Amicus Therapeutics To Advance Pharmacological Chaperone Technology
4. Cystic Fibrosis Foundation Launches National Cycling Series to Benefit Critical Research and Care
5. National Patient Safety Foundation Awards Grant to Research Safety of Computerized Ordering of Medications
6. North Carolina GlaxoSmithKline Foundation Working With Nonprofits to Promote Health, Science and Education Through Ribbon of Hope Grants
7. TransMedics, Inc. Secures $36 Million Round of Financing Lead by Foundation Capital and Kleiner Perkins Caufield & Byers
8. Physicians Foundation Warns of Potential Impact From New Medicare Cuts Effective Today
9. Oral Cancer Foundation Donates Screening Devices to West Virginia Free Clinics
10. Centene Foundation for Quality Healthcare Awards Grant to Fragile Kids Foundation
11. Limbs for Life Foundation Presents the Roaring 20s at 9th Annual Benefit Gala and Auction
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):