Navigation Links
Foundation Venture Capital Group Investment Shows Promise in Diagnosis of Alzheimer's Disease Using a Drop of Blood
Date:8/3/2011

NEW BRUNSWICK, N.J., Aug. 3, 2011 /PRNewswire-USNewswire/ -- A new diagnostic test for Alzheimer's disease (AD)  developed by biotech company Durin Technologies in New Jersey has shown promising results using antibody biomarkers in a drop of blood to identify presence of the disease, according to findings that appear online in PLoS ONE.

The research was made possible through an investment by Foundation Venture Capital Group (FVCG), LLC, a New Jersey Health Foundation affiliate that invests in start-up companies founded by researchers at the University of Medicine and Dentistry of New Jersey.  

"This research is an exciting step in AD diagnosis that seems extremely promising based on preliminary results," said James M. Golubieski, president of Foundation Venture Capital Group. "If, after further study, Dr. Nagele's research bears out, his success could help ease the suffering of millions of people worldwide as they struggle with this devastating illness."

Dr. Robert Nagele, founder of Durin Technologies and a researcher at the New Jersey Institute for Successful Aging at the UMDNJ-School of Osteopathic Medicine in Stratford, NJ, focuses his efforts on the concept that autoantibodies are involved in the degenerative mechanism of AD.

Study results published in PLoS ONE show the test, which uses microarray technology to analyze a small sample of blood, has a diagnostic sensitivity of 96 percent and a specificity of 92.5 percent and may be able to detect the disease even in its earliest stages, years before symptoms such as memory loss, poor judgment or erratic behavior appear.

"There's a dire need for an accurate, relatively non-invasive and inexpensive diagnostic test for AD," explained Dr. Nagele.  "A test that can detect the disease years before symptoms appear would make early intervention possible, a significant breakthrough as pharmaceutical companies are now working feverishly to develop new drugs that can stop or slow the progression of the disease."

As many as 5.3 million Americans, and 35 million people worldwide, are living with Alzheimer's disease, a devastating neurodegenerative illness characterized by memory loss, cognitive decline and widespread destruction of neurons in the brain.  

"Today, there is no definitive diagnosis for AD and no treatment to cure it," said George F. Heinrich, M.D., vice chair and chief executive officer of Foundation Venture Capital Group.  "We are thrilled to have played such an important role in helping to make this discovery possible.  It could represent a huge leap forward in the efforts to thwart this devastating disease."

For more information, contact James M. Golubieski, president of FVCG, at (908) 731-6601 or at jgolubieski@njhf.org.

About Foundation Venture Capital Group
Foundation Venture Capital Group, an affiliate of New Jersey Health Foundation, was founded in 2006 to invest in commercially viable new start-up companies developing technology by faculty at UMDNJ. In addition to Durin Technologies, it has invested in:  

  • Actinobac Biomed Inc., developing a therapeutic agent targeting blood cells for the treatment of hematological malignancies;  the same agent seems to help in the treatment of other autoimmune diseases like psoriasis
  • Affineti Biologics, Inc., advancing research in the development of therapeutic and diagnostic products based on new discoveries in oral biology and dental medicine
  • CellXplore, Inc., engaged in the development of biomarker-based in vitro diagnostic assays for cancer; it has also developed technologies to diagnose mastitis
  • Celvive, Inc., working to develop technology to treat patients with chronic spinal cord injuries with their own adult stem cells
  • Longevica Pharmaceuticals, Inc., developing a chemoprotective agent that may keep normal cells healthy during cancer treatments (FVCG's equity interest in Longevica was sold to Rostock International, LTD, a subsidiary of a Moscow (Russia) based global investment firm)
  • Snowdon Pharmaceuticals, a drug discovery company focused on several major therapeutic areas.


'/>"/>
SOURCE New Jersey Health Foundation
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Kevin McHale Instrumental in Forming the Help Me Hear Foundation
2. AIDS Healthcare Foundation Names Homayoon Khanlou, M.D. as its Chief of Medicine, U.S.
3. CellCyte Genetics Corp. Enters Collaborative Research Agreement With Cleveland Clinic Foundation to Qualify Stem Cell Delivery in Damaged Heart Tissue
4. Nobel Prize Awarded to Foundation for Biomedical Research Board Member
5. The Oral Cancer Foundation Urges HPV Vaccination for Males
6. MedicAlert Foundation Joins The Alzheimers Association to Offer MedicAlert(R) + Alzheimers Association Safe Return(R) - Live 24-Hour Emergency Response for Wandering and Medical Emergencies
7. Phase 1 & 2 Data of Perifosine (KRX-0401) in Patients with Advanced Renal Cell Carcinoma Presented Today at the 25th Annual Chemotherapy Foundation Symposium
8. Grantees of the Avon Foundation Breast Cancer Prevention Research Initiative Gather in Houston to Report Interim Findings
9. Five Clinical Studies to Receive $2.5 Million Under Foundations 2007 Clinical Discovery Program
10. Alpha-1 Foundation, AARC Cooperate on Study to Test 5,000 COPD Patients for Alpha-1
11. Arthritis Foundation Announces Amgen and Wyeth to Be Presenting Sponsor of the 2008 Arthritis Walk (R)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/19/2017)... , Jan. 19, 2017 Conference Call and Webcast to ... ) today announced it will release results for the fourth quarter ... ... host a conference call at 4:30 PM ET on Wednesday, February ... full year 2016 financial results and other corporate activities. To participate ...
(Date:1/19/2017)... , Jan. 19, 2017 This report ... current and future scenario of the global market. Large ... opioid consumption. Severe chronic constipation is a major side ... traditional laxatives. Hence, novel targeted therapy has been prescribed ... sufferers, launch of targeted medicines, and growing awareness about ...
(Date:1/19/2017)...  Stealth BioTherapeutics Inc. ( Stealth ), a clinical-stage ... announced new additions to its senior leadership team: ... and Daniel Geffken as interim Chief Financial ... , Pharm.D. has been promoted to Chief Clinical Development ... Doug and Daniel to our management team, as both ...
Breaking Medicine Technology:
(Date:1/21/2017)... ... ... Seamild, the largest manufacturer of oats in China, is now aiming at global ... is recognized globally as one of the healthiest cereals, XieQingkui, the founder of Seamild, ... move to sow the seed of good karma. Buddhism spirit featuring benevolence and sacrifice ...
(Date:1/21/2017)... Pekin, IL (PRWEB) , ... January 21, 2017 , ... ... disorders. Even when individuals experience the freedom of recovery, they often feel shame for ... abuse and post-traumatic stress disorder (PTSD). In the workshop, “Rising Strong in Life After ...
(Date:1/20/2017)... ... January 20, 2017 , ... Source Vitál Apothecary, a skin and ... essential oils, announced the company had a successful visit to the 2017 ECRM Diet, ... gives companies that work in the nutritional, sports and health industries a chance to ...
(Date:1/20/2017)... ... January 20, 2017 , ... International Protein, a company based out ... announced it attended the January ECRM trade show in Hilton Head, SC. , ... was determined to create a line of products that would elevate her fitness regime. ...
(Date:1/20/2017)... ... ... “The Angel”: a heartwarming and earnest tale of faith and believing in the ... is the creation of published author, Marjorie Lund-Fontaine, a former professional violinist, alumnus of ... asked of her new book, Marjorie says, “‘The Angel’ was written as a fairytale, ...
Breaking Medicine News(10 mins):