Navigation Links
ForteBio Launches Dip and Read™ Anti-GST Biosensor
Date:11/29/2011

MENLO PARK, Calif., Nov. 29, 2011 /PRNewswire/ -- ForteBio®, Inc., a leading supplier of label-free technology that accelerates the development of biotherapeutic and pharmaceutical products, today announced the introduction of its Dip and Read™ Anti-GST biosensor for use on the company's Octet® instrumentation platform. The new biosensor enables researchers to conduct quantitation and kinetic analyses with GST fusion proteins – widely used assays to detect protein interactions – with unprecedented ease of use, high-throughput and cost efficiency.

"Our new, robust Anti-GST biosensor enables researchers to determine expression levels of GST-tagged proteins and cell lines in a matter of minutes, rather than hours that are typically required using standard ELISA methods, and then perform rigorous kinetic characterization of the selected clones immediately afterwards," said Christopher Silva, ForteBio's vice president of marketing. "This versatility is especially conducive to high-throughput analyses and enables users to greatly streamline their laboratory workflow to deliver results more quickly."

The Anti-GST biosensor enables easy and rapid quantitation of GST-tagged proteins in buffer, media or bacterial lysates, while facilitating kinetic characterization of macromolecular interactions between GST-tagged proteins and target analytes. Each biosensor can be regenerated up to 10 times during kinetic analysis with a standard low-pH protocol, for maximum cost-efficiency.

The company also announced the launch of its Amine Reactive Second-Generation (AR2G) biosensor, also for use on the company's Octet systems. This new biosensor enables kinetic characterization of macromolecular interactions between purified proteins and target analytes, with similar robustness and high-throughput as the company's Streptavidin biosensor while allowing an alternative biosensor surface when desired for specific ligands.

"Our AR2G biosensor enables researchers to conduct rapid immobilization of proteins and peptides for screening or kinetic experiments with greater ease of use, cost-efficiency and throughput than allowed by traditional methods," said Mr. Silva. "Further, with its newly engineered biocompatible surface matrix, the AR2G biosensor provides enhancements over our first-generation AR biosensor, including greater signal intensity during the loading (immobilization of ligand) and association (detection of analyte) steps of an assay, increased loading density, decreased non-specific binding, and increased stability in a wide range of pH and salt conditions."

ForteBio's Octet platform is based on the company's proprietary BioLayer Interferometry (BLI) technology, which uses optical biosensors to measure multiple interactions in parallel, without the use of detection agents. The Octet platform consists of 8- and 16-channel instruments that accommodate 96- and 384-well assay formats. All Octet biosensors are designed to simplify kinetic characterization and quantitation by eliminating throughput and time-to-result limitations of traditional SPR-based assays and ELISA. The Octet biosensors are disposable, configured in a standard microplate format and are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding.

ABOUT FORTEBIO, INC.

ForteBio is a life science company that provides analytical systems to accelerate biotherapeutic drug discovery and development. These systems enable real-time, label-free analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. ForteBio's analytical capabilities enable significantly easier, faster and better characterization of drug candidates, thus providing greater value in drug development applications where existing methods have limitations in throughput, performance and cost. The company is headquartered in Menlo Park, California, with wholly owned subsidiaries in London and Shanghai. For more information, visit www.fortebio.com.


'/>"/>
SOURCE ForteBio, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. ForteBio Launches New Dip and Read(TM) Residual Protein A Detection Kit; Introduces Sidekick(TM) Offline Biosensor Immobilization Station for All Octet(R) Instruments
2. ForteBio Announces Launch of Protein G Biosensor for Use on Companys Octet® Instruments
3. ForteBio Launches New Octet® RED96 System and Dip and Read™ Protein L Biosensor
4. ForteBio Introduces New Biosensor for Kinetic Analysis and Screening of Mouse IgG Antibodies
5. Iomai Launches Phase 1/2 Safety Study of Dose-Sparing Patch for Use With Pandemic Influenza Vaccine
6. Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces
7. Cell Therapeutics, Inc. (CTI) Launches Phase III Study for Pixantrone in Relapsed Indolent Non-Hodgkins Lymphoma (NHL)
8. Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
9. Strategic Diagnostics Launches Initial Oncology-Targeted Antibody Reagent Catalog
10. deCODE Launches Phase II Clinical Testing of DG051 for the Prevention of Heart Attack
11. Premier Micronutrient Launches Supplement for Hearing Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
(Date:6/23/2016)... , June 23, 2016 ... Oticon , industry leaders in advanced ... launch of Oticon Opn ™, the world,s first ... of possibilities for IoT devices.      (Photo: ... Oticon introduces a number of ,world firsts,: ...
Breaking Medicine Technology:
(Date:6/24/2016)... ... ... in a crisis. Her son James, eight, was out of control. Prone to extreme mood ... something upset him, he couldn’t control his emotions,” remembers Marcy. “If there was a ... children and say he was going to kill them. If we were driving on ...
(Date:6/24/2016)... San Francisco, CA (PRWEB) , ... June 24, ... ... at CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has ... , self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... People across ... in Genome magazine’s Code Talker Award, an essay contest in which patients and their ... award to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Investment Group (TGIG), has initiated cultivation and processing operations at its production facility, ... Pahrump, Nevada. , Puradigm is the manufacturer of a complete system of proactive ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) sponsors ... on June 20th at the Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, ... to helping service members that have been wounded in battle and their families. Venture ...
Breaking Medicine News(10 mins):