Navigation Links
ForteBio Launches Dip and Read™ Anti-GST Biosensor
Date:11/29/2011

MENLO PARK, Calif., Nov. 29, 2011 /PRNewswire/ -- ForteBio®, Inc., a leading supplier of label-free technology that accelerates the development of biotherapeutic and pharmaceutical products, today announced the introduction of its Dip and Read™ Anti-GST biosensor for use on the company's Octet® instrumentation platform. The new biosensor enables researchers to conduct quantitation and kinetic analyses with GST fusion proteins – widely used assays to detect protein interactions – with unprecedented ease of use, high-throughput and cost efficiency.

"Our new, robust Anti-GST biosensor enables researchers to determine expression levels of GST-tagged proteins and cell lines in a matter of minutes, rather than hours that are typically required using standard ELISA methods, and then perform rigorous kinetic characterization of the selected clones immediately afterwards," said Christopher Silva, ForteBio's vice president of marketing. "This versatility is especially conducive to high-throughput analyses and enables users to greatly streamline their laboratory workflow to deliver results more quickly."

The Anti-GST biosensor enables easy and rapid quantitation of GST-tagged proteins in buffer, media or bacterial lysates, while facilitating kinetic characterization of macromolecular interactions between GST-tagged proteins and target analytes. Each biosensor can be regenerated up to 10 times during kinetic analysis with a standard low-pH protocol, for maximum cost-efficiency.

The company also announced the launch of its Amine Reactive Second-Generation (AR2G) biosensor, also for use on the company's Octet systems. This new biosensor enables kinetic characterization of macromolecular interactions between purified proteins and target analytes, with similar robustness and high-throughput as the company's Streptavidin biosensor while allowing an alternative biosensor surface when desired for specific ligands.

"Our AR2G biosensor enables researchers to conduct rapid immobilization of proteins and peptides for screening or kinetic experiments with greater ease of use, cost-efficiency and throughput than allowed by traditional methods," said Mr. Silva. "Further, with its newly engineered biocompatible surface matrix, the AR2G biosensor provides enhancements over our first-generation AR biosensor, including greater signal intensity during the loading (immobilization of ligand) and association (detection of analyte) steps of an assay, increased loading density, decreased non-specific binding, and increased stability in a wide range of pH and salt conditions."

ForteBio's Octet platform is based on the company's proprietary BioLayer Interferometry (BLI) technology, which uses optical biosensors to measure multiple interactions in parallel, without the use of detection agents. The Octet platform consists of 8- and 16-channel instruments that accommodate 96- and 384-well assay formats. All Octet biosensors are designed to simplify kinetic characterization and quantitation by eliminating throughput and time-to-result limitations of traditional SPR-based assays and ELISA. The Octet biosensors are disposable, configured in a standard microplate format and are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding.

ABOUT FORTEBIO, INC.

ForteBio is a life science company that provides analytical systems to accelerate biotherapeutic drug discovery and development. These systems enable real-time, label-free analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. ForteBio's analytical capabilities enable significantly easier, faster and better characterization of drug candidates, thus providing greater value in drug development applications where existing methods have limitations in throughput, performance and cost. The company is headquartered in Menlo Park, California, with wholly owned subsidiaries in London and Shanghai. For more information, visit www.fortebio.com.


'/>"/>
SOURCE ForteBio, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. ForteBio Launches New Dip and Read(TM) Residual Protein A Detection Kit; Introduces Sidekick(TM) Offline Biosensor Immobilization Station for All Octet(R) Instruments
2. ForteBio Announces Launch of Protein G Biosensor for Use on Companys Octet® Instruments
3. ForteBio Launches New Octet® RED96 System and Dip and Read™ Protein L Biosensor
4. ForteBio Introduces New Biosensor for Kinetic Analysis and Screening of Mouse IgG Antibodies
5. Iomai Launches Phase 1/2 Safety Study of Dose-Sparing Patch for Use With Pandemic Influenza Vaccine
6. Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces
7. Cell Therapeutics, Inc. (CTI) Launches Phase III Study for Pixantrone in Relapsed Indolent Non-Hodgkins Lymphoma (NHL)
8. Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
9. Strategic Diagnostics Launches Initial Oncology-Targeted Antibody Reagent Catalog
10. deCODE Launches Phase II Clinical Testing of DG051 for the Prevention of Heart Attack
11. Premier Micronutrient Launches Supplement for Hearing Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... , Feb. 23, 2017  Cogentix Medical, Inc. (NASDAQ: ... markets innovative proprietary products for the urology market, will ... year ended December 31, 2016 before the market open ... Company will host a conference call and webcast to ... March 9, 2017 at 11:00 a.m. Eastern Time (10:00 ...
(Date:2/23/2017)... -- Research and Markets has announced the addition of the ... their offering. ... research Menopause Drugs Price Analysis and Strategies - 2016, provides drug pricing ... the following questions: What are the key ... in the Global Menopause market? What are the unit ...
(Date:2/23/2017)... DUBLIN , Feb. 23, 2017 Research ... Price Analysis and Strategies - 2016" report to their offering. ... The latest ... pricing data and benchmarks in the global Fibromyalgia market. ... are the key drugs marketed for Fibromyalgia and their clinical attributes? ...
Breaking Medicine Technology:
(Date:2/24/2017)... ... , ... With millions of Americans and people worldwide struggling ... are aware of our options and are empowered with strength and information throughout ... its newest edition of "Vision and Hearing" in USA Today, that will educate ...
(Date:2/24/2017)... ... , ... The narrative in “ Signal 8: An Australian Paramedic’s Story ” ... paramedic experiences. Schanssema describes the tragedies he saw, as well as his struggles with ... Schanssema, initially unsure of the career path he wanted to take, found fulfillment in ...
(Date:2/24/2017)... ... February 24, 2017 , ... The California State University ... academic faculty engaged in or interested in palliative care education and research. The Symposium, ... held in North County San Diego on Sept. 28 and 29, 2017, on the ...
(Date:2/24/2017)... ... ... The International Association of Eating Disorders Professionals (iaedp) announces the 2017 top five ... art competition. Selected from 15 submissions from around the nation, the top five finalists ... iaedp Symposium, March 22 – 26 in Las Vegas. , This year, the competition ...
(Date:2/24/2017)... ... 2017 , ... The Radiology Business Management Association will select the ... annual Building Better Radiology Marketing Programs conference, held this year from March ... Nine awards are given out in five categories. They are:, , ...
Breaking Medicine News(10 mins):