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ForteBio Introduces New Biosensor for Kinetic Analysis and Screening of Mouse IgG Antibodies
Date:6/8/2011

MENLO PARK, Calif., June 8, 2011 /PRNewswire/ -- ForteBio®, Inc., a leading supplier of label-free technology that accelerates the development of biotherapeutic and pharmaceutical products, today announced the launch of its Dip and Read™ Anti-Mouse IgG Fc Capture (AMC) biosensor for use on the company's Octet® instrumentation platform. The new biosensor enables high-throughput rapid kinetic characterization and screening of mouse antibodies and other Fc-containing proteins with unprecedented ease of use and cost efficiency.

"With the introduction of our new AMC biosensor, researchers can now benefit from ForteBio's off-the-shelf, label-free biosensors during discovery projects using murine models, as well as when working with human antibodies," said Christopher Silva, ForteBio's vice president of marketing, noting that the company already offers its Anti-Human IgG Fc Capture (AHC) biosensor for analysis of human IgG antibodies. "Our AMC biosensor eliminates the need for inconvenient, labor-intensive steps typically associated with ELISA and SPR methods for screening and kinetic characterization, and thereby facilitates high-throughput research applications such as hybridoma screening and characterization."

The new AMC biosensor enables immobilization of mouse Fc-containing proteins upon the biosensor directly, from a crude or purified matrix, without the need to biotinylate. Additionally, AMC biosensors can be regenerated and reused up to 10 times.

"Our new AMC biosensor can also work fluidly with ForteBio's other research tools for increased speed, ease of use and cost efficiency," said Mr. Silva. "For example, researchers using our Protein G biosensor to titer hybridoma samples can now use our AMC biosensor to perform kinetics and affinity analysis on resulting epitopes of interest – all from the same crude sample."

ForteBio's Anti-Human IgG Fc Capture biosensor is ready to use on the company's Octet instrument
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SOURCE ForteBio, Inc.
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