Navigation Links
ForteBio Introduces New Biosensor for Kinetic Analysis and Screening of Mouse IgG Antibodies
Date:6/8/2011

MENLO PARK, Calif., June 8, 2011 /PRNewswire/ -- ForteBio®, Inc., a leading supplier of label-free technology that accelerates the development of biotherapeutic and pharmaceutical products, today announced the launch of its Dip and Read™ Anti-Mouse IgG Fc Capture (AMC) biosensor for use on the company's Octet® instrumentation platform. The new biosensor enables high-throughput rapid kinetic characterization and screening of mouse antibodies and other Fc-containing proteins with unprecedented ease of use and cost efficiency.

"With the introduction of our new AMC biosensor, researchers can now benefit from ForteBio's off-the-shelf, label-free biosensors during discovery projects using murine models, as well as when working with human antibodies," said Christopher Silva, ForteBio's vice president of marketing, noting that the company already offers its Anti-Human IgG Fc Capture (AHC) biosensor for analysis of human IgG antibodies. "Our AMC biosensor eliminates the need for inconvenient, labor-intensive steps typically associated with ELISA and SPR methods for screening and kinetic characterization, and thereby facilitates high-throughput research applications such as hybridoma screening and characterization."

The new AMC biosensor enables immobilization of mouse Fc-containing proteins upon the biosensor directly, from a crude or purified matrix, without the need to biotinylate. Additionally, AMC biosensors can be regenerated and reused up to 10 times.

"Our new AMC biosensor can also work fluidly with ForteBio's other research tools for increased speed, ease of use and cost efficiency," said Mr. Silva. "For example, researchers using our Protein G biosensor to titer hybridoma samples can now use our AMC biosensor to perform kinetics and affinity analysis on resulting epitopes of interest – all from the same crude sample."

ForteBio's Anti-Human IgG Fc Capture biosensor is ready to use on the company's Octet instruments. ForteBio's Octet platform is based on the company's proprietary BioLayer Interferometry (BLI) technology, which uses optical biosensors to measure multiple interactions in parallel, without the use of detection agents. The Octet platform consists of 8- and 16-channel instruments that accommodate 96- and 384-well assay formats. All Octet biosensors are designed to simplify kinetic characterization and quantitation by eliminating throughput and time-to-result limitations of traditional SPR-based assays and ELISA. The Octet biosensors are disposable, configured in a standard microplate format and are coated with a proprietary biocompatible matrix that is uniform, non-denaturing and has minimal non-specific binding.

ABOUT FORTEBIO, INC.

ForteBio is a life science company that provides analytical systems to accelerate biotherapeutic drug discovery and development. These systems enable real-time, label-free analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. ForteBio's analytical capabilities enable significantly easier, faster and better characterization of drug candidates, thus providing greater value in drug development applications where existing methods have limitations in throughput, performance and cost. The company is headquartered in Menlo Park, California, with wholly owned subsidiaries in London and Shanghai. For more information, visit www.fortebio.com.


'/>"/>
SOURCE ForteBio, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. ForteBio Launches New Dip and Read(TM) Residual Protein A Detection Kit; Introduces Sidekick(TM) Offline Biosensor Immobilization Station for All Octet(R) Instruments
2. ForteBio Announces Launch of Protein G Biosensor for Use on Companys Octet® Instruments
3. ForteBio Launches New Octet® RED96 System and Dip and Read™ Protein L Biosensor
4. Quest Diagnostics Introduces ClariSure(TM) Test for Identifying Chromosome Abnormalities Associated With 85 Developmental Disorders in Children
5. Dr. Dello Russo Introduces the New EYE-Q Lasik
6. Caliper Life Sciences Introduces Drug Combination Services to Identify Synergistic Response of Compounds
7. Wedgewood Introduces Refresh(TM) Exchange-Program: Free Exchange of Expired Veterinary Compounded Medications Solves Key Industry Problem
8. CeloNova BioSciences Introduces a New Class of Coronary Stent: The CATANIA(TM) Coronary Stent System with NanoThin Polyzene(R)-F
9. Thermo Fisher Scientific Introduces Breakthrough in RNA-Interference Technology
10. Schering-Plough Provides Update on Boceprevir Clinical Development and Introduces Potent Next-Generation Oral HCV Protease Inhibitor for Treating Patients With Chronic Hepatitis C
11. Siemens Introduces New Standard of Care for Breast Ultrasound
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/13/2017)... 2017 Constant research ongoing in the ... contribute to the demand for western blotting technique. The global  ... US$ 551.0 Mn by 2016 end. Developing economies in ... markets for western blotting, whereas North America ... ...
(Date:1/13/2017)... 13, 2017  Alfalfa, cattle, leafy greens and rosy cheeked ... film , which emphasizes the food industry,s shift from response ... COPAN,s Swab Rinse Kit (SRK™) ... sampling process in the wake of the new FDA ... COPAN is expanding the U.S. production of the ...
(Date:1/13/2017)... -- This morning, Stock-Callers.com draws attention to ... at yesterday,s closing bell: Clovis Oncology Inc. (NASDAQ: ... GALE ), and ACADIA Pharmaceuticals Inc. (NASDAQ: ... to develop technologies and products that combat debilitating and ... use less and cleaner energy, and provide safer, cleaner ...
Breaking Medicine Technology:
(Date:1/15/2017)... , ... January 15, 2017 , ... The Gravity Vault ... in Radnor, Pennsylvania. As construction wraps up on the 14,000+ square foot climbing gym, ... Vaults sixth location, including three in New Jersey and two in New York. With ...
(Date:1/14/2017)... ... January 13, 2017 , ... According to ... magnesium-rich Mediterranean diet may lower the risk of type 2 diabetes, Alzheimer’s, and ... many health and wellness benefits linked to a Mediterranean diet are only some ...
(Date:1/13/2017)... California (PRWEB) , ... January 13, 2017 , ... ... carbohydrates that raise blood sugar levels. Counting carbohydrates is as easy as checking ... the only nutrient that affects blood sugar levels. Despite being sugar-free, proteins can ...
(Date:1/13/2017)... ... ... KOAMTAC ®, Inc., a leading manufacturer of Bluetooth barcode scanners and mobile ... collector at the National Retail Federation’s Big Show (NRF17) held January 15-17 in New ... need for more compact and rugged devices for collecting barcode data paired with a ...
(Date:1/13/2017)... , ... January 13, 2017 , ... An inventor from ... black or brown belt in order to diversify my outfits, so he decided to ... wear. , THE T.O.O.B. enhances the appearance of a belt to allow for quick, ...
Breaking Medicine News(10 mins):