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For Treatment of Extensive-Disease Small-Cell Lung Cancer (ED-SCLC), No Emerging Therapy is Likely to Replace Etoposide/Carboplatin as the Standard of Care Before 2022
Date:4/23/2013

art such substantial gains.

The report also finds that most surveyed managed care organization (MCO) pharmacy directors would consider reimbursing new therapies at a substantial premium to the current standard of care if such drugs can impart meaningful gains in survival relative to etoposide/carboplatin. Surveyed payers indicated that ED-SCLC therapies that impart an OS benefit could command price premiums as high as 20 times the cost of etoposide/carboplatin regimen and still be able to obtain reimbursement. This willingness to include premium-priced drugs on formulary reflects the dearth of therapies for ED-SCLC that improve survival relative to etoposide/carboplatin.

"A major problem in the treatment of ED-SCLC is the development of chemoresistant disease," said Decision Resources Senior Analyst Regina Jammen . "Finding therapies that can be used upfront for newly diagnosed patients that do not induce resistance would be a real benefit to patients. Such a therapy would likely not provide a cure but oncologists and patients alike would value new therapies that extend survival beyond what we are seeing now. It is reassuring to know that payers would accept substantial price increases over current treatments for innovative therapies and would include them on formulary, even if cost controls slow uptake of these potential new therapies."

About Decision Resources
Decision Resources (www.decisionresources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources Group company.

About Decision Resources Group
Decision Resources Group is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely
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