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For Osteoporosis and Osteopenia, Clinical Data and Thought Leaders' Opinions Indicate that AMG-785/CDP-7851 and Odanacatib Have Advantages Over Alendronate
Date:4/4/2013

BURLINGTON, Mass., April 4, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed U.S. and European primary care physicians (PCPs) agree that efficacy on hip fracture risk reduction is one of the attributes that most influences their decisions regarding prescribing in osteoporosis and osteopenia. Clinical data and the opinions of interviewed thought leaders indicate that Amgen/UCB's AMG-785/CDP-7851 and Merck's odanacatib have advantages over patient share leader alendronate (Merck's Fosamax, Teijin's Bonalon, generics) on this attribute.

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The DecisionBase 2013 report entitled Emerging Therapies AMG-785/CDP-781 and Odanacatib Are Poised to Overtake Teriparatide's Status as the Clinical Gold Standard also finds that, based on clinical data and the opinions of interviewed thought leaders, teriparatide (Eli Lilly's Forteo/Forsteo, Asahi Kasei's Teribone) is Decision Resources' current proprietary clinical gold-standard therapy for osteoporosis and osteopenia. Teriparatide has the strongest clinical profile among key marketed products that treat osteoporosis and osteopenia. However, AMG-785/CDP-7851 is expected to displace teriparatide and will earn proprietary clinical gold-standard status for osteoporosis and osteopenia in 2021, following its launch for the indication in 2017. AMG-785/CDP-7851 has competitive advantages in safety and tolerability as well as delivery over teriparatide and advantages in efficacy and safety over the current standard of care, alendronate.

"It is important to note, however, that AMG-785/CDP-7851 is considered only marginally better than odanacatib, which fa
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SOURCE Decision Resources
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