Navigation Links
Five-Year Data Confirm That Early Treatment with Betaseron(R) at First Sign of Disease Can Delay Progression to MS
Date:9/20/2008

early departure from the workforce. Patients treated early with Betaseron fared better in tests of cognitive function compared to those with delayed treatment, which is good news for people with MS," Dr. Freedman said.

The BENEFIT study was the first to demonstrate a reduction in the risk of confirmed EDSS progression, as measured by the Expanded Disability Status Scale (EDSS), with early versus delayed treatment. This effect first appeared at year three, with a significant risk reduction of 40 percent (p=0.022).(2) Over five years, a nominal risk reduction of 24 percent (p=0.177) was observed for early treatment compared to delayed treatment. This difference over five years was not statistically significant.(1)

The key findings from the BENEFIT five-year study showed that:(1)

-- Starting Betaseron after the first clinical event delayed the development of CDMS by more than two years (750 days) in the 40th percentile.

-- Patients treated early with Betaseron had a greater reduction in relapse rate over five years compared to patients with delayed treatment, (0.21 versus 0.27) despite the latter receiving at least three years of treatment after the second attack or after two years (p=0.014; Poisson model). This effect was mainly due to the differences between the groups during the first two years.

-- Early treatment significantly reduced the development of newly active brain lesions (new or enlarging T2 lesions, Gd-enhancing lesions) compared to delayed treatment (p=0.0062).

-- In the BENEFIT study there was a high level of study completion of Betaseron by patients with the earliest signs of MS. Two-thirds of patients (67 percent) in the early treatment group continued on Betaseron for five years.

-- Patients consistently reported a high Health-Related Quality of Life over the five-year study period.

Adverse events (AEs) reported at five years were consistent with the product label.

About BENEFIT

B
'/>"/>

SOURCE Bayer HealthCare Pharmaceuticals Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Cypher(R) Sirolimus-Eluting Coronary Stent Demonstrates Sustained Clinical Benefits Compared to Bare Metal Stents in Five-Year Randomized Clinical Trial With No Differences in Long-Term Safety
2. Five-Year Data From Taxus II Clinical Trial Highlights Safety and Efficacy of Taxus(R) Stent Compared to Bare-Metal Stent
3. Positive Xeloda(R) Five-Year Overall Survival Study Data in the Adjuvant Treatment of Colon Cancer Presented at Leading European Cancer Meeting
4. Positive Five-Year Safety Data for TAXUS(R) Stent Reported in Boston Scientific Trial
5. Five-Year Data Demonstrate Long-Term Efficacy and Safety with ORENCIA(R) (abatacept) in Adults with Rheumatoid Arthritis Who had an Inadequate Response to Methotrexate
6. Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006
7. NeurogesX Completes Enrollment in Confirmatory Phase 3 Clinical Trial for Painful HIV Distal Sensory Polyneuropathy
8. NeurogesX Completes Enrollment in Confirmatory Phase 3 Clinical Trial for Painful HIV Distal Sensory Polyneuropathy
9. KineMed Presents Preclinical Data for Investigational Agent Demonstrating Neurogenesis and Confirming Improvements in Behavioral Model
10. New Clinical Studies Confirm Mauna Kea Technologies Cellvizio(R) GI in Range of Procedures
11. IDM Pharma Announces Updated Phase 3 Mifamurtide (L-MTP-PE) Data Confirms Statistically Superior Overall Survival in Osteosarcoma Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)...  Growth of the U.S. nonprescription market is primarily ... users to the OTC market. Due to an increasingly ... switch activity over the next five years with several ... brands entering the market into existing categories. ... (even those with low to moderate likelihood), the market ...
(Date:7/30/2015)... N.J. , July 30, 2015  Medimetriks ... completed the second Phase III clinical study for ... for impetigo.  Medimetriks owns the exclusive U.S. rights ... global trial, conducted at 44 centers with an ... pediatric patients aged 2 months and older with ...
(Date:7/30/2015)... 2015 Vermillion, Inc. (VRML), a ... announced today it will report its second ... close on Thursday, August 13, 2015, followed ... at 4:30pm Eastern.Conference Call and Webcast:  ... Pacific  Domestic: , 888-430-8691International: ...
Breaking Medicine Technology:Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 2Rx-to-OTC Switches -- Game Changers for the U.S. OTC Drugs Market through 2019, Sees Kline 3Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 2Medimetriks Pharmaceuticals, Inc. Announces Completion of the Second Successful Pivotal Phase III Study for Ozenoxacin 3
... TLC Vision announced today its plans for opening a ... Diego.  Internationally recognized as leaders in field of refractive surgery, ... will lend their surgical skill and expertise to the TLC ... continue to be at the forefront of working with optometry ...
... Kaiser Permanente,s National Pharmacy Programs and Services was recognized at ... Vegas as a J.D. Power 2011 Customer Service Champion ... the distinction this year. To qualify for ... within their own industries, but also must stand out among ...
Cached Medicine Technology:TLC Vision Announces TLC Laser Eye Center San Diego 2Kaiser Permanente Recognized as a J.D. Power 2011 Customer Service Champion 2
(Date:7/31/2015)... ... July 31, 2015 , ... The Radiology Business Management ... MD, (R-Tex) presenting “What’s Next for Health Care: A View From Capitol Hill” on ... of the Congressional Health Caucus, Rep. Burgess has a special understanding of the real ...
(Date:7/31/2015)... ... July 31, 2015 , ... Super-Sod wants to participate in planning new ... Page as the perfect fit for such a goal. Houzz is a social ... website is a dynamic site that spreads home and home garden design ideas when ...
(Date:7/31/2015)... ... 2015 , ... Easter Seals Southern Georgia’s Heels & Wheels Duathlon & Triathlon will be held ... 7:30 AM. The duathlon is a 2 mile run, 13 mile bike ride, and a ... 13 mile bike, and a 3 mile run. Heels & Wheels is sponsored by ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... ... The same logic applies when purchasing disability insurance, where price is an important ... Consultants, along with a leading insurance carrier, offers the Preferred Producer Multi-Life Discount ...
(Date:7/30/2015)... ... July 31, 2015 , ... When responsible for the care ... out-of-reach. The questions race through your mind: What happens if mom falls? Who will ... overwhelmed and cancel your plans. , But not taking time away from caregiving responsibilities ...
Breaking Medicine News(10 mins):Health News:Congressional Health Caucus Founder Rep. Michael Burgess, MD, to Speak at RBMA Fall Educational Conference 2Health News:Congressional Health Caucus Founder Rep. Michael Burgess, MD, to Speak at RBMA Fall Educational Conference 3Health News:Super-Sod Created a Landscape Profile on Houzz.com for Home Garden Design 2Health News:Heels & Wheels for Megan's House Set for Saturday August 22, 2015 in Waycross, Georgia 2Health News:Secura Consultants Gives Advisers Competitive New Edge with Multi-Life Discount Program 2Health News:Aging Life Care Association™ Experts Offer Tips for Caregivers in Need of Vacation Time 2Health News:Aging Life Care Association™ Experts Offer Tips for Caregivers in Need of Vacation Time 3
... ... for creation of offshore worker safety task force to promote interest of oil rig crews ... ... in the Gulf of Mexico once again illustrates the hazardous and sometimes deadly work conditions ...
... two-thirds of women of childbearing age fit the bill ... study says federal guidelines on obesity should be revised ... , U.S. guidelines determine who is obese based on ... and weight are proportional. The researchers found that about ...
... past over the issue , WEDNESDAY, April 21 (HealthDay ... Wednesday proposed new guidelines to help give the public ... its all-important advisory committees, which help approve drugs and ... criticized for allowing individuals with conflict of interests to ...
... ... ... wellness programs depends not only on motivating employees, but also on how supportive companies ... Seven Ways to Build a High-Engagement Wellness Program , scheduled for Thursday, April 22 at ...
... cause pneumonia and meningitis, researchers point out , WEDNESDAY, April ... the PCV7 vaccine to battle bacteria that causes pneumonia, ... changes in strains that cause these illnesses, researchers report. , ... by the vaccine, the team aid. , Immunizations with the ...
... at Johns Hopkins say they have discovered the way in ... following a stroke. , Two hours after feeding mice ... the skins and seeds of red grapes, the scientists induced ... the animals, brains. They found that the animals that had ...
Cached Medicine News:Health News:Explosion on Gulf Coast Oil Rig Underscores Daily Dangers for Maritime Workers, Say Houston Maritime Injury Lawyers Arnold & Itkin LLP 2Health News:More U.S. Women May Be Obese Than Thought 2Health News:FDA to Broaden Disclosure on Advisers' Conflicts of Interest 2Health News:FDA to Broaden Disclosure on Advisers' Conflicts of Interest 3Health News:DSM Personalized Nutrition Webinar Examines Ways to Build Engagement in Wellness Programs 2Health News:DSM Personalized Nutrition Webinar Examines Ways to Build Engagement in Wellness Programs 3Health News:Vaccine Now Misses Many Pneumococcal Infections in Kids 2Health News:How red wine may shield brain from stroke damage 2