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First Reportable Data of EarlyCDT™-Lung Use in Clinical Practice Presented at IASLC World Conference on Lung Cancer
Date:7/5/2011

re not as precise as we would like and any tool that allows us to further risk stratify these nodules is of value," he added.  

Oncimmune's EarlyCDT-Lung test uses a panel of tumor antigens to detect the presence of immuno-biomarkers produced in the form of autoantibodies by the patient's immune system.  Elevation of any one of the panel of immuno-biomarkers (autoantibodies) above a predetermined cut-off value suggests that a tumor might be present and the lung nodule is malignant.  Previous studies have shown that immuno-biomarkers can be detected up to five years before tumors can be seen in routine diagnostic imaging procedures such as computed tomography (CT).

The audit included results from EarlyCDT-Lung's initial 6-antigen panel and the current 7-antigen panel that enables greater than 90% accuracy.  EarlyCDT-Lung has 93% specificity, resulting in seven times fewer false positives and three times better positive predictive value than CT. One thousand and ten (1010) patients in North America at high risk of lung cancer, on the basis of age and smoking history, from 293 centers across 40 states had EarlyCDT-Lung measured (start date May 2009). All patients signed a HIPAA release agreeing to their clinical information being accessed as part of this prospective audit.

According to John Robertson, M.D., FRCS, Chief Scientific Officer and founder of Oncimmune and Professor of Surgery, City Hospital, University of Nottingham, United Kingdom, "Collective data published in the Annals of Oncology, Clinical Cancer Research and an 'in press' manuscript with Cancer Prevention Research continue to demonstrate the depth of our scientific data and it
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SOURCE Oncimmune (USA) LLC
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