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First Patient Enrolled in Multi-Center Clinical Trial of the CorMatrix® ECM® for Pericardial Closure to Reduce the Incidence of New Onset Postoperative Atrial Fibrillation
Date:12/13/2010

We've seen the significant results of the retrospective study published in Heart Surgery Forum and are encouraged by CorMatrix's commitment to pursue a prospective trial.  We are excited to participate in this study because we believe reconstructing the pericardium with CorMatrix ECM will provide tremendous benefit to our patients," said Manesh Parikshak, MD, Cardiothoracic Surgeon at the Franciscan Alliance/St. Francis Heart Center, Indianapolis, and co-investigator for the trial. "This is a particularly important trial given the clinical and economic implications of new onset postoperative AF, and we are pleased to have enrolled the first patient."

CorMatrix ECM, a naturally occurring bioscaffold, has been successfully implanted in more than 25,000 patients in the U.S.  It helps stimulate tissue growth by providing a location where the patient's cells can migrate and integrate with the ECM, eventually creating new tissue in place of the CorMatrix ECM.  

"The unique properties of the CorMatrix ECM provide an excellent opportunity to repair the pericardium and reduce postoperative atrial fibrillation," said Marc Gerdisch, MD, Director of Cardiothoracic Surgery at the Franciscan Alliance/St. Francis Heart Center, Indianapolis, and overall Principal Investigator of the trial. "This trial has the potential to revolutionize treatment options for postoperative AF patients."

About Extracellular Matrix Biomaterial

The unique properties of extracellular matrix biomaterials were discovered at Purdue University. The decellularized matrix material serves as a scaffold to allow adjacent tissues to deliver cells and nutrients to the matrix, which then differentiate into tissue-specific cells. The ECM material is gradually replaced, as the patient's own body reinforces and rebuilds the weakened site. During the repair, the matrix is naturally degraded and resorbed, leaving remodeled functional tissue where scar ti
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SOURCE CorMatrix Cardiovascular, Inc.
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