First-Line Use of Abilify Has More Than Doubled Over the Past Year for the Treatment of Newly-Diagnosed Patients in Bipola... ( BURLINGTON Mass. Nov. 16 2010 /- De...)

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First-Line Use of Abilify Has More Than Doubled Over the Past Year for the Treatment of Newly-Diagnosed Patients in Bipolar Disorder

Date:11/16/2010

BURLINGTON, Mass., Nov. 16, 2010 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that first-line use of Bristol Myers-Squibb/Otsuka's Abilify has increased over the past year in newly-diagnosed patients from 4.1 percent patient share to 8.8 percent. According to Treatment Algorithms in Bipolar Disorder, uptake of Abilify in the first-line will continue among surveyed primary care physicians (PCPs): 26 percent of surveyed PCPs who prescribe Abilify indicate they expect to increase their first-line use of this agent over the next two years.

Overall use of Abilify is expected to increase over the next two years as well: 25 percent and 50 percent of surveyed psychiatrists and PCPs, respectively, expect their overall use of Abilify to increase. Surveyed physicians also indicate that use of AstraZeneca's Seroquel XR will grow substantially over the same time period with 28 percent of surveyed psychiatrists and 56 percent of surveyed PCPs expecting that their overall use of Seroquel XR will increase. Additional growth for Seroquel XR will be through greater use in the first line in both psychiatrists and PCPs: 29 percent of surveyed psychiatrists and 36 percent of surveyed PCPs who prescribe Seroquel XR indicate that they expect to increase their use of the agent in the first line over the next two years.

"In light of the anticipated increased use of Seroquel XR, we expect that AstraZeneca's Seroquel will lose some patient share to Seroquel XR, but that loss will not be large enough to unseat Seroquel from its lead position among atypicals. Uptake will be further challenged once generics of Seroquel become available in 2012," said Decision Resources Analysis Alana Simorellis, Ph.D. "Surveyed psychiatrists score Abilify preferentially in terms of ris
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