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First Large-Scale Population-Based Study in the U.S. Shows Hologic's 3D Mammography (Breast Tomosynthesis) Significantly Reduces Recall Rates While Simultaneously Improving Cancer Detection
Date:5/23/2013

BEDFORD, Mass., May 23, 2013 /PRNewswire/ -- Hologic, Inc. (Hologic or the Company) (NASDAQ: HOLX), a leading developer, manufacturer and supplier of premium diagnostics, medical imaging systems and surgical products, with an emphasis on serving the healthcare needs of women, today announced that the first large-scale observational study in a U.S. clinical practice comparing breast cancer screening with Hologic's 3D mammography technology (breast tomosynthesis) with conventional 2D mammography alone showed a significant reduction in recall rates and a sizeable increase in cancer detection, particularly invasive cancer, across all breast tissue densities. Published in the June issue of the American Journal of Roentgenology (AJR), the study evaluated recall, biopsy, cancer detection and invasive cancer detection rates in a community-based breast imaging practice. The study was issued online in advance of print on May 23, 2013.

The study, "Implementation of Breast Tomosynthesis in a Routine Screening Practice: An Observational Study"[i] was led by Stephen L. Rose , M.D., President and Founder of Rose Imaging, Medical Director of TOPS Comprehensive Breast Center, and Breast Radiologist affiliated with Memorial Hermann Health System in Houston, Texas. The analysis compared the outcomes of 2D mammography screening exams that were interpreted prior to the introduction of Hologic's 3D mammography, with screening exams after the introduction of 3D mammography into the practice.

The Rose study found that the use of Hologic's 3D mammography resulted in:

  • A  significant 38% drop in recall rates – from 8.7% to 5.5% (p < 0.001)
  • An 11%  drop in biopsy rates - from 15.2 to 13.5 per 1,000 screenings (p = 0.59)
  • A 35% increase in cancer
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  • SOURCE Hologic, Inc.
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