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First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity
Date:3/23/2010

with severe spasticity have seen a reduction spasticity-related pain.[11] In multiple sclerosis and spinal injury, patients experienced a 92 percent decrease in their spasticity symptoms following ITB Therapy.[12]

ITB Therapy has also been shown to improve mobility, daily functioning and quality of life, to ease patients' pain and decrease dependency on nursing care.[10,13] ITB Therapy has been shown to minimize the economic burden of spasticity, [13] by helping physicians and caregivers improve function and comfort in patients. [11]

Some patients may experience ITB therapy drug side effects which are usually temporary and manageable by adjusting the dose. The most common side effects include loose muscles, drowsiness, nausea/vomiting, headache and dizziness. Close attention to physician's instructions is required since abrupt cessation of intrathecal baclofen can result in high fever, altered mental status, returned spasticity, and muscle rigidity, and in rare cases has been fatal. The implanted infusion system may result in complications such as infection (including meningitis), overdose or underdose resulting from programming errors or system component failures and cerebral spinal fluid leakage resulting in a spinal headache.

To date, ITB Therapy has been widely used to treat spasticity which could not be sufficiently contro
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SOURCE Medtronic Inc.
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