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First European Patients Enrolled in Largest Ever Randomised Controlled Trial of ITB Therapy(R) in Post-Stroke Patients With Severe Spasticity
Date:3/23/2010

cause of disability, with 15 million new cases each year worldwide,[5] and over one million people suffering a stroke in Western Europe every year.[6] Of these patients, up to 65 percent will suffer from spasticity as a result,[3] and for many of them, oral medication and/or physical therapy combined are not enough to manage spasticity.4 Post-stroke spasticity patients have reduced function and lower quality of life than patients without the disability.[7,8]

ITB Therapy is an approved treatment for patients with severe generalized spasticity associated with multiple sclerosis, cerebral palsy, spinal cord injury, brain injury, and stroke who do not respond to oral medication. ITB Therapy treats severe non-focal spasticity through a programmable pump, which is placed under the skin of the abdomen and connected to a catheter.

Once in place, the pump and catheter deliver anti-spastic medication directly to the site of action in the cerebrospinal fluid surrounding the spinal cord, where it may be is most effective.[9] Due to its direct administration into the spine, ITB Therapy requires a lower dosage of medication compared to oral treatments, while producing a similar reduction in spasticity with fewer possible side effects than what is often seen with higher doses of oral baclofen.[9]

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SOURCE Medtronic Inc.
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