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First Cancer Diagnostic Test Based on Rosetta Genomics' Proprietary MicroRNA Technology Receives Regulatory Approval
Date:7/22/2008

Test Developed and Validated by Columbia University Medical Center Based on

Rosetta Genomics' Proprietary MicroRNA Technology The Test Differentiates Squamous From Non-Squamous Non-Small Cell Lung

Cancer (NSCLC), Classifying Squamous-Cell Carcinoma of the Lung With

Sensitivity of 96 Percent and Specificity of 90 Percent This is the First CLIA Approved Test Which Leverages MicroRNAs' Sensitivity

as Biomarkers for Accurate Diagnosis of Lung Cancer

REHOVOT, Israel and JERSEY CITY, New Jersey, July 22 /PRNewswire-FirstCall/ -- Rosetta Genomics, Ltd. (NASDQ: ROSG) announces today that the first molecular test based on Rosetta Genomics' proprietary microRNA technology, developed and validated by Columbia University Medical Center (CUMC), has been approved for clinical use by the New York State Department of Health Clinical Laboratory Evaluation Program. CUMC is now finalizing the commercial aspects of this test and will announce its clinical availability to patients nationwide once details are finalized later this year.

"This is a landmark event for us, marking the first step in the transformation of Rosetta Genomics into a commercial diagnostics company," said Amir Avniel, President and CEO of Rosetta Genomics. "Our proprietary microRNA platform technologies, which this test is based on, have enabled Columbia University Medical Center's High Complexity Molecular Pathology Laboratory to develop a highly sensitive and specific test, which is a key for optimal administration of targeted therapies for this devastating cancer. As we move forward, we expect our development engines to enable the launch of additional tests based on our technology that have the potential to improve patient care worldwide."

The test, performed on a sample of a patient's tumor, classifies squamous-cell carcinoma of the lung with sensitivity of 96 percent and specificity of 90 percent. This is the first test utilizing microRNA
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SOURCE Rosetta Genomics Ltd
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