Navigation Links
Fertility Drugs Contribute Heavily to Multiple Births

March of Dimes Concerned About Drugs' Role in Crisis of Prematurity

WHITE PLAINS, N.Y., June 16 /PRNewswire-USNewswire/ -- The widespread use of fertility drugs, not just high-tech laboratory procedures, plays a major role in causing multiple births and  contributes to the problem of premature birth in the United States, experts said today at the March of Dimes National Communications Advisory Council luncheon.

Working with experts from the U.S. Centers for Disease Control and Prevention (CDC), Joann Petrini, PhD, assistant director of research at Danbury Hospital in Connecticut and an advisor to the March of Dimes, found that controlled ovarian hyperstimulation (COH) drugs — which are used to stimulate a woman's ovaries to speed the maturity and multiply the production of eggs — account for four times more live births than assisted reproductive technologies (ARTs) such as in vitro fertilization. 

"Many people have focused on the role of ARTs in multiples and have not fully appreciated that fertility drugs alone are responsible for one out of every five multiple births," said Dr. Petrini. "There is a very high possibility of multi-fetal pregnancy resulting from these drugs, and that brings a high risk of prematurity and lifelong health problems for the babies as a consequence."

Patients should inform their doctors that their goal is a single baby and that they wish them to use treatments that minimize the risk of multiple pregnancy, said Richard Dickey, MD, PhD, medical director of The Fertility Institute of New Orleans and Clinical Professor of Obstetrics and Gynecology at the Louisiana State University Health Sciences School of Medicine at New Orleans.

"A doctor's goal when prescribing fertility drugs is one healthy baby," said Dr. Dickey. "Doctors should not hesitate to cancel ovulation stimulation cycles and to tell their patients to avoid trying to get pregnant if an ultrasound shows there are too many eggs present in a cycle and the risk of multiples is high. "The March of Dimes urges more research and leadership from professional societies to develop specific guidelines and encourage acceptance of best practices for the proper use and dosage of fertility drugs, as well as the careful counseling and monitoring of women treated with these drugs.  Also, the March of Dimes said a system is needed to monitor how many multiples births are caused by fertility drugs and to hold professionals accountable to industry guidelines. Women who are taking fertility drugs should always ask their doctor what they can do to prevent having a multi-fetal pregnancy.

About 88,000 babies are born preterm annually as a result of the recent increase of twins, triplets, and other multiple births.  About 60 percent of twins, more than 90 percent of triplets and virtually all quadruplets and higher-order multiples are born prematurely. In addition to the increased risks associated with multiple birth, studies have also suggested that even infants born singly but conceived with ovulation stimulation are at increased risk for preterm birth than naturally conceived single births, the study authors pointed out.

The March of Dimes said it is critical for the American Society for Reproductive Medicine, the American College of Obstetricians and Gynecologists, and other clinical societies to develop clear guidelines on the use of fertility drugs to help prevent many premature births.

More than 540,000 babies are born too soon each year in the United States.  Preterm birth costs the nation more than $26 billion annually, according to the Institute of Medicine. It is the leading cause of newborn death, and babies who survive an early birth face the risk of lifelong health problems, such as breathing problems, mental retardation, cerebral palsy, developmental delays, and vision and hearing loss.  Even babies born just a few weeks too soon (34-36 weeks gestation, also known as late preterm birth) have higher rates of death and disability than full-term babies.  

The March of Dimes is the leading nonprofit organization for pregnancy and baby health.  With chapters nationwide, the March of Dimes works to improve the health of babies by preventing birth defects, premature birth and infant mortality.  For the latest resources and information, visit or For free access to national, state, county and city-level maternal and infant health data, visit PeriStats, at

SOURCE March of Dimes
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Center for Fertility Preservation Uses Breakthrough Egg Freezing Technology to Offer Women a Viable Backup Plan
2. Merck Receives European Approval for ELONVA(R) (corifollitropin alfa injection), a New Fertility Treatment
3. Fertility Physicians of Northern California Researchers Test New Forms of Progesterone Medication for Luteal Support During IVF
4. Nationwide Survey Shows Infertility Patients Prefer ENDOMETRIN(R) Compared With Other Progesterone Supplements
5. FDA Clears ExAblate Fertility Enhancement Study in Women With Uterine Fibroids
6. American Fertility Association Calls for Expanded Research to Advance New Technology to Screen Embryos for Genetic Abnormalities
7. John DeVincenzo, MD, at the University of Tennessee Health Science Center Discovers First Evidence that RNA-interference Drugs Reduce Human Disease
8. FDA Announces Collaboration With
9. In a World First, Asda Announces Not for Profit Price on All Cancer Treatment Drugs
10. Reportlinker Adds Global HIV Drugs industry
11. Reportlinker Adds Ophthalmic Therapeutic Drugs: Technologies and Global Markets
Post Your Comments:
(Date:11/24/2015)... COMMACK , Nueva York ... Avery Biomedical Devices (ABD), fabricante del Avery Breathing ... Anders Jonzon , MD; Ph.D. como consultor ...   --> Foto - ... --> El doctor Jonzon es un ...
(Date:11/24/2015)... 2015 Sectra (STO: SECT B) ... into a multi-year agreement to deploy Breast Imaging ... provide the Breast Center a future-proof platform capable of ... SECT B) announces that Breast Center of Acadiana ... Breast Imaging PACS in its two freestanding imaging centers. This ...
(Date:11/24/2015)... and BERN, Switzerland , November 24, ... Center for Biomedical Engineering Research of the University of ... of Endocrinology, Diabetes and Clinical Nutrition of the Bern ... of an exclusive collaboration to develop a novel generation ... the personalised delivery of insulin for diabetic patients with ...
Breaking Medicine Technology:
(Date:11/25/2015)... ... ... On November 23rd 2015 Cozy Products, a division of Bird-X Incorporated, ... explains what this means for business moving forward. , The Tri Lite heater business ... to sell personal heaters that reduce energy consumption, are economical and keep people warm ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... of music, friendships, and learning in its 65th Anniversary Brillianteen Revue, scheduled for ... , For 65 years, Brillianteen has been a treasured tradition for ...
(Date:11/25/2015)... ... 25, 2015 , ... Castlewood Treatment Center for Eating Disorders, ... as a result of the $20,000 raised at the center’s recent golf ... Club in Eureka, will help individuals who otherwise might not seek treatment for ...
(Date:11/25/2015)... ... ... An unlikely combination of recycled plastic shopping bags in ... to have a more dignified and comfortable night’s sleep. , Residents of Friendship ... bags into sleeping mats for the homeless. The project, according to Jeannette ...
(Date:11/25/2015)... ... November 25, 2015 , ... Students and parents have something ... winners of the Create Real Impact awards. California Casualty is proud to ... the tide of distracted and reckless driving, the number one killer of young drivers. ...
Breaking Medicine News(10 mins):