Navigation Links
Ferring Pharmaceuticals and Gene Security Network Partner to Test Advanced Preimplantation Genetic Diagnosis (PGD) Technology
Date:2/25/2010

PARSIPPANY, N.J. and REDWOOD CITY, Calif., Feb. 25 /PRNewswire/ -- Ferring Pharmaceuticals and Gene Security Network (GSN) announced that they have signed an agreement to conduct a clinical trial of GSN's advanced preimplantation genetic diagnosis (PGD) technology, Parental Support™.  The 11-center U.S. trial is designed to evaluate if GSN's PGD technology helps increase in vitro fertilization (IVF) success rates when using single cell embryo testing for an abnormal number of chromosomes, a condition called aneuploidy.  GSN's Parental Support technology is designed to help improve embryo selection during IVF procedures in order to increase the pregnancy rate following embryo transfer compared with IVF procedures without embryo PGD testing.  

"As the market leader in innovative infertility products, we are delighted to partner with GSN to help evaluate this unique product for the fertility medical community and patients," said Olivier Delannoy, Vice President, Infertility Business Unit at Ferring.  "GSN's technology is supported by impressive data, and may enable reproductive endocrinologists to achieve more accurate embryo selection, and hopefully lead to higher live birth rates.  We are hopeful that this upcoming clinical trial will support the positive early data generated for the PGD technology."  

"Our agreement with Ferring provides the framework for our testing technology to become state of the art treatment for infertility patients.  By using Parental Support to select embryos that have the best chance of developing into a healthy pregnancy, we hope to augment Ferring's drug therapy regimen and boost pregnancy rates," said Matthew Rabinowitz, PhD, Chief Executive Officer of Gene Security Network.  "Our early data from 24-chromosome aneuploidy screening with Parental Support resulted in a 50 percent ongoing pregnancy rate for patients undergoing PGD, most of whom have had problems with previous IVF cycles.  We are looking forward to initiating the prospective randomized trial in May."

Under the terms of the agreement, every trial patient will exclusively use Ferring fertility products for their IVF cycle, receiving the medications at a discounted rate.  Ferring will also provide financial support and assistance in finalizing the trial protocol and monitoring the trial's progress, with the option to partner with GSN in distribution of Parental Support upon conclusion of the study.  

About Preimplantation Genetic Diagnosis

Preimplantation genetic diagnosis (PGD) is a technique used to identify genetic defects before pregnancy in embryos created through IVF.  PGD represents a means to help prevent genetic disease before implantation, thereby helping reduce the need to address the dilemma of pregnancy termination following an unfavorable prenatal diagnosis.  PGD for aneuploidy refers to techniques where embryos from presumed chromosomally normal genetic parents are screened for aneuploidy.  Most early pregnancy failures can be attributed to aneuploidy.  Primary candidates for PGD can include: women of advanced maternal age, couples with a history of recurrent pregnancy loss, couples with repeated IVF failure, and a male partner with severe male factor infertility.  The risk of aneuploidy in embryos increases as women age.  The aneuploidy rate for mothers aged 35-39 years is greater than 70 percent, and is over 80 percent in mothers aged 40 years and older.(1)

About Ferring Pharmaceuticals Inc.

Ferring Pharmaceuticals Inc. is a subsidiary of Ferring Pharmaceuticals, a privately owned, international pharmaceutical company.  Ferring Pharmaceuticals offers a line of products in the U.S. market.  They include: BRAVELLE® (urofollitropin for injection, purified), MENOPUR® (menotropins for injection, USP) and REPRONEX® (menotropins for injection, USP), Novarel® (chorionic gonadotropin for injection, USP), ENDOMETRIN® (progesterone) Vaginal Insert, 100 mg, FIRMAGON® (degarelix for injection), PROSED® DS (methenamine, phenyl salicylate, methylene blue, benzoic acid, hyoscyamine sulfate), DESMOPRESSIN, and EUFLEXXA® (1% sodium hyaluronate).

Ferring Pharmaceuticals specializes in the research, development and commercialization of compounds in general and pediatric endocrinology, urology, orthopaedics, gastroenterology, obstetrics/gynecology, and infertility.  For more information, call 1-888-FERRING (1-888-337-7464) or visit www.FerringUSA.com or www.ferringfertility.com.

About Gene Security Network

GSN's proprietary Parental Support™ technology is the first to leverage data informatics to deliver highly accurate single cell testing for chromosome abnormalities and genetic diseases.  Parental Support uses genetic information from the parents, as well as HapMap data from the Human Genome Project, to clarify the typically noisy measurements from a single cell and to generate an in silico reconstruction of the cell's genotype.  GSN operates a CLIA-certified laboratory in Redwood City, CA and is supported by multiple grants from the National Institutes of Health and leading venture investors, including Claremont Creek Ventures and Sequoia Capital.  For more information, please visit www.genesecurity.net.

(1) Cohen et al. Fertility and Sterility 2007;87;496-503.

SOURCE Ferring Pharmaceuticals

Back to top

RELATED LINKS
http://www.FerringUSA.com
http://www.ferringfertility.com

'/>"/>

SOURCE Ferring Pharmaceuticals
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. deCODE and Radboud University Discover Common Variants in the Human Genome Conferring Risk of Bladder Cancer
2. Ferring Pharmaceuticals Launches Phase IIIB Trial of Degarelix as Intermittent Therapy
3. Ferring Pharmaceuticals Unveils Six-Month Efficacy Data for EUFLEXXA(R) for the Treatment of Osteoarthritis Knee Pain
4. Timm Medical Technologies and Ferring Pharmaceuticals Enter Exclusive Co-Promotion Agreement for Prosed(R) DS
5. Dr. Harry Kovelman Joins Ferring Pharmaceuticals as Associate Medical Director for Orthopaedics
6. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
7. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
8. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
9. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
10. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
11. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... The key factors driving the growth of dialysis ... growth and increasing healthcare expenditure. Some of the noteworthy trends ... ESRD patients, rising demand for home PD treatment and huge ... market is hindered by high treatment costs and stringent regulations. ... Complete ...
(Date:3/23/2017)... March 23, 2017  Transportation Insight, a multi-modal lead ... supply chain management firm with expertise serving clients in ... Rick Zaffarano was named a 2017 ... Chain by the only publication exclusively dedicated to covering ... chain. "Rick has brought to Transportation Insight ...
(Date:3/23/2017)... INDIANAPOLIS , March 23, 2017  Eli ... the William Sansum Diabetes Center have established a research ... by diabetes through enhanced research, education and care. ... disease bears a disproportionate weight on Latino families in ... David Kerr , M.D., FRCPE, director of Innovation and ...
Breaking Medicine Technology:
(Date:3/23/2017)... ... ... The physicians of KSF Orthopaedic Center PA are proud to announce the opening ... at 2255 E. Mossy Oaks Rd., Suite 440, Spring, Texas 77389 inside the new ... in the north Houston area (The Woodlands, Conroe, Magnolia, Kingwood, Humble) with an even ...
(Date:3/23/2017)... ... March 23, 2017 , ... PAINWeekEnd ... at 10 North Broadway Avenue, will be an educational and exciting program providing ... in the management of chronic pain. , Oklahoma is in a healthcare crisis. ...
(Date:3/23/2017)... ... ... of adults are unaware of the dangers that infectious bacteria play in mouth disease, while ... a day that dentists recommend. The ramifications of improper oral upkeep go far beyond bad ... 164 million hours of work each year due to dental issues. That is why Mediaplanet ...
(Date:3/23/2017)... ... March 23, 2017 , ... Benefits delivery trailblazer, ... mobile app and centralized benefits dashboard solving one of the top frustrations in ... locations. For the first time, employees can access up-to-date information and account balances ...
(Date:3/23/2017)... Malvern, PA (PRWEB) , ... March 23, 2017 ... ... a comprehensive educational training program owned and organized by HMP Communications Holdings, LLC, ... training program for physicians within its nationwide network of wound centers interested in ...
Breaking Medicine News(10 mins):