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Feasibility of Artificial Pancreas System Demonstrated in Real-World Setting
Date:6/11/2012

NEW YORK, June 11, 2012 /PRNewswire-USNewswire/ --JDRF, a global leader in type 1 diabetes(T1D) research, is pleased to announce that an outpatient study being conducted at multiple academic institutions has demonstrated the safety and feasibility of artificial pancreas (AP) device testing on an ambulatory basis. The research, funded by JDRF, was presented this weekend at the 72nd American Diabetes Association (ADA) Scientific Sessions.

The pilot study, the first ever to be conducted on an outpatient basis, is being conducted concurrently at the Montpellier University Hospital (France) and the University of Padova (Italy), with additional testing being done at the University of Virginia and Sansum Diabetes Research Institute (United States). The goal of the study is to test the feasibility of an AP system that links an insulin pump with a blood glucose sensor through special software housed in a smart phone. The smart phone acts as a control device with the ability to monitor blood glucose levels and control the administration of insulin wirelessly, while a 3G connection allows remote monitoring of the system by the investigational team.

The presentation at the ADA Scientific Sessions focused on two study participants who used the AP continuously out of the hospital for 18 hours, including during dinner, an overnight stay in a hotel, breakfast, and a morning walk. One patient was able to remain within near-normal values throughout the entire period of evaluation, while the other patient was kept within near-normal range 78 percent of the time. Neither patient required medical intervention.

"What we have seen in these studies is that the artificial pancreas is safe and feasible for the purposes of outpatient testing in a 'real-world' environment—an important milestone," noted Dr. Aaron Kowalski, assistant vice president of treat therapies at JDRF. "JDRF is looking forward to the completion of these pilot studies both in Europe and in the
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SOURCE Juvenile Diabetes Research Foundation
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