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FDA approves drug tested by Scottsdale Healthcare and TGen
Date:9/6/2013

linical trials, including those managed by Translational Drug Development (TD2), the pharmaceutical-development subsidiary of TGen.

"We are proud to have helped navigate the regulatory requirements and study protocols that helped ensure that Abraxane was not only effective, but also safe for patients with advanced pancreatic cancer," said Dr. Stephen Gately, President and CEO of TD2. "This is one of the most significant advancement in the treatment of pancreatic cancer since the FDA approved gemcitabine in 1996."

Dr. Von Hoff, considered among the nation's leading authorities on pancreatic cancer, also was the principal investigator for the first clinical trial of gemcitabine, the first therapy to show improvement in survival for patients with pancreatic cancer.

The pancreas is a glandular organ behind the stomach that secretes enzymes to help digestion, and produces hormones, including insulin, which helps regulate blood-sugar metabolism. 

Abraxane wraps traditional chemotherapy, paclitaxel, in near-nano sized shells of albumin, a protein that the tumor recognizes as food. Once inside the tumor, the Abraxane acts like a "Trojan Horse" to release chemotherapy and kill the cancer cells.

Abraxane, made by Celgene Corporation, previously was approved by the FDA for use in the treatment of metastatic breast cancer and advanced lung cancer.

About the Virginia G. Piper Cancer Center at Scottsdale Healthcare
The Virginia G. Piper Cancer Center at Scottsdale Healthcare in Scottsdale, Ariz. offers comprehensive cancer treatment and research through clinical trials, diagnosis, treatment, prevention and support services in collaboration with leading scientific researchers and community oncologists. Scottsdale Healthcare is the nonprofit parent organization of the Virginia G. Piper Cancer Center at Scottsdale Healthcare, Scottsdale Healthcare R
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SOURCE Scottsdale Healthcare
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