Navigation Links
FDA approves GlaxoSmithKline's VOTRIENT(TM) for advanced renal cell cancer
Date:10/19/2009

PHILADELPHIA, Oct. 19 /PRNewswire-FirstCall/ -- GlaxoSmithKline (NYSE: GSK) announced today that the U.S. Food and Drug Administration (FDA) has approved VOTRIENT(TM) (pazopanib) to treat patients with advanced renal cell carcinoma (RCC), a form of kidney cancer. Approximately 57,700 people in the U.S. will be diagnosed with kidney cancer this year, and 13,000 people will die from this disease.

"RCC is the most common malignancy of the kidney and is highly resistant to chemotherapy," said Paolo Paoletti, MD, Senior Vice President, GlaxoSmithKline Oncology R&D Unit. "While treatment has improved in the past few years with the introduction of targeted therapies, advanced RCC remains a challenging disease. VOTRIENT will join existing targeted therapies to provide physicians with a new oral treatment option to their patients with advanced renal cell cancer."

VOTRIENT, a once-daily, oral medication, is an angiogenesis inhibitor which may help prevent the growth of new blood vessels, thereby blocking the growth of kidney cancer tumors that need blood vessels to survive.

The approval of VOTRIENT was supported by a unanimous decision by the FDA's Oncology Drugs Advisory Committee (ODAC) that the benefit-to-risk profile for VOTRIENT is acceptable for patients with advanced kidney cancer. The ODAC reviewed data from a Phase III clinical trial showing that VOTRIENT reduced the risk of tumor progression or death by 54 percent compared to placebo, regardless of prior treatment.

In this Phase III trial, the overall median PFS was 9.2 months with pazopanib and 4.2 months with placebo. Treatment-naive patients who received VOTRIENT experienced 11.1 months of median progression-free survival (PFS) versus 2.8 months with placebo. Additionally, patients who had previously received cytokine-based treatment achieved 7.4 mo
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. FDA Approves Seasonal Influenza Vaccine Fluarix for Pediatric Use
2. FDA Approves New Treatment for Advanced Form of Kidney Cancer
3. FDA Approves Elitek(R) (rasburicase) for Management of Plasma Uric Acid Levels in Adults with Leukemia, Lymphoma, and Solid Tumors Receiving Anti-Cancer Therapy
4. FDA Approves Cervarix, GlaxoSmithKlines Cervical Cancer Vaccine
5. U.S. Food and Drug Administration Approves CRESTOR(R) for Use in Pediatric Patients With Heterozygous Familial Hypercholesterolemia
6. Chinese Food and Drug Administration Approves Gabexate Mesylate as Pharmaceutical Raw Material
7. FDA Approves New Indication For Mirena(R) to Treat Heavy Menstrual Bleeding in IUD Users
8. US FDA Approves Extavia(R) - the First in a New Portfolio of Planned MS Therapies from Novartis to Help Patients with this Devastating Disease
9. Video: FDA Approves INVEGA(R) SUSTENNA(TM) for the Acute and Maintenance Treatment of Schizophrenia
10. FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent
11. FDA Approves ADCIRCA(TM) (Tadalafil) Tablets for the Treatment of Pulmonary Arterial Hypertension
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... , Jan. 23, 2015 More than a third of ... of those with private insurance, filled a prescription for an ... report in this week,s Morbidity and Mortality Weekly Report (MMWR). ... providers to treat moderate to severe pain.  They are also ...
(Date:1/23/2015)... GAINESVILLE, Fla. , Jan. 23, 2015  HyGreen, Inc., ... distribution agreement and partnership with RCA Medical, a subsidiary ... Africa . Each year, hundreds of ... health care-associated infections as organisms are transmitted from patient ...
(Date:1/23/2015)... 2015 Cord Blood America, Inc. ( www.cordblood-america.com ) (OTC ...  filed a Preliminary Proxy Statement, Schedule 14A, with the U.S. ... an update for shareholders detailing why a "YES" vote to ... Dear Shareholders, As we reflect upon the 2014 ...
Breaking Medicine Technology:Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3HyGreen Partners with RCA Medical in Johannesburg, South Africa 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4
... Laboratories, L.C. and Intercell AG (VSE; "ICLL") ... of Romark,s antiviral drug, nitazoxanide, in combination ... (HCV) vaccine, IC41, during the first half ... (Logo: http://www.newscom.com/cgi-bin/prnh/20100201/FL47022LOGO) Intercell,s vaccine ...
... Oct. 21 IDEV Technologies, Incorporated (IDEV), an innovative ... medical technologies, today announced another step in the implementation ... treating patients with peripheral vascular disease with the addition ... The initial uses of the newly introduced 180mm and ...
Cached Medicine Technology:Romark and Intercell Join Forces in Combining Therapies Against Hepatitis C 2Romark and Intercell Join Forces in Combining Therapies Against Hepatitis C 3Romark and Intercell Join Forces in Combining Therapies Against Hepatitis C 4Romark and Intercell Join Forces in Combining Therapies Against Hepatitis C 5IDEV Technologies Launches Additional Products in Europe 2
(Date:1/22/2015)... 2015 AngelWeddingDress, the premier women’s dress ... wedding dresses. View website of AngelWeddingDress.com to ... maternity wedding dresses online for a bridal party. AngelWeddingDress ... quality for them. Its maternity wedding dresses are specially ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 A new ... of experience and person-centeredness in the long-term care environment ... action across the continuum. The paper, “The Power of ... engages perspectives and practices of the patient, resident and ...
(Date:1/22/2015)... Oceanside,CA (PRWEB) January 22, 2015 For over 20 ... the Oceanside and Vista area has treated just about ... other personal injury circumstances. And for those same twenty-plus years, ... victims of all those injuries with the best possible doctor. ...
(Date:1/22/2015)... 2015 A study recently published ... journal Medicine & Science in Sports & Exercise ... help reduce gastrointestinal (GI) problems associated with physical ... in the double-blind, placebo-controlled study took 10 grams ...
(Date:1/22/2015)... 22, 2015 IsoComforter, Inc. has introduced the ... patented IsoTube design to treat specific body parts and muscle ... progressive and easy to use patented cold therapy machine with ... related orthopedic and muscle injuries. IsoComforter has become the ...
Breaking Medicine News(10 mins):Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Industry Leading Chiropractor in Oceanside Joins the Doctors on Liens Network 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2
... ... ... ... ...
... ... , ... -- Eisner USA, LLC ( http://www.eisnerusa.com ) announced the release of its latest innovative product ... imaging data and the best of video game technology to create vivid 3D visualization used ...
... ... Big White accommodation for Spring Break family ski vacations: superb ski-in / ski-out location; fully ... hot tubs, waterslide and movie theatre; easy access to Big White,s mountain playground; and now ... ...
... ... Specialty Health (ASH), a leading national health and wellness company, has selected White ... to offer personal health records connected to Microsoft HealthVault as a part of ... health record to health plans, insurance carriers, and employer groups. , ...
... ... Sigma Black Belt training and certification to its portfolio of online and live courses on ... learning experience for students and also provides benefits to employers. , ... Tucson, AZ (PRWEB) March 3, 2010 -- The Pyzdek ...
... Top Dog ... ... Foundation , a Nashville-based nonprofit dedicated to helping pets in need of care, invites you ... 10-week fundraising campaign, dogs and cats vie for the coveted title of “Top Dog” or ...
Cached Medicine News:Health News:Biostar Pharmaceuticals, Inc. to Present at the 2010 Rodman & Renshaw Annual China Investment Conference in Beijing 2Health News:Biostar Pharmaceuticals, Inc. to Present at the 2010 Rodman & Renshaw Annual China Investment Conference in Beijing 3Health News:Biostar Pharmaceuticals, Inc. to Present at the 2010 Rodman & Renshaw Annual China Investment Conference in Beijing 4Health News:Biostar Pharmaceuticals, Inc. to Present at the 2010 Rodman & Renshaw Annual China Investment Conference in Beijing 5Health News:Biostar Pharmaceuticals, Inc. to Present at the 2010 Rodman & Renshaw Annual China Investment Conference in Beijing 6Health News:Biostar Pharmaceuticals, Inc. to Present at the 2010 Rodman & Renshaw Annual China Investment Conference in Beijing 7Health News:Biostar Pharmaceuticals, Inc. to Present at the 2010 Rodman & Renshaw Annual China Investment Conference in Beijing 8Health News:CT and MRI Images Now Seen in a 3D Virtual Reality World 2Health News:CT and MRI Images Now Seen in a 3D Virtual Reality World 3Health News:Last Minute Deals for Spring Break at Sundance at Big White Ski Resort 2Health News:American Specialty Health (ASH) Selects SPINNphr for Integrated Personal Health Record Solution 2Health News:American Specialty Health (ASH) Selects SPINNphr for Integrated Personal Health Record Solution 3Health News:American Specialty Health (ASH) Selects SPINNphr for Integrated Personal Health Record Solution 4Health News:Pyzdek Institute Releases Online Lean Six Sigma Black Belt Training 2Health News:Pyzdek Institute Releases Online Lean Six Sigma Black Belt Training 3Health News:ATTENTION: Pawty Animals Needed in Nashville, Tennessee 2Health News:ATTENTION: Pawty Animals Needed in Nashville, Tennessee 3
... Automatic dispenser for low volumes. Dispenses ... 1536 -well format. Fast throughput of less ... productivity. The dispenser features an intuitive user ... be used to dispense liquids and suspensions, ...
... is the newest addition to Thermos Multidrop ... microvolumes of 1-50 l into 384- and ... in a 384-well plate takes only 14 ... and accuracy typically 10% at 2 l, ...
Multidrop DW is a high-speed automated dispenser for Deep Well plates, 1.1 ml test tubes and 96-well plates. Designed for accuracy and precision, the Multidrop DW dispenses up to eight different reag...
RIA kit for the determination of autoantibodies to the muscle-specific receptor tyrosine kinase....
Medicine Products: