Navigation Links
FDA Grants Orphan Drug Designation for Mithridion's MCD-386CR to Treat Progressive Supranuclear Palsy
Date:5/8/2011

MADISON, Wis., May 9, 2011 /PRNewswire/ -- Mithridion, Inc., a privately-owned clinical stage drug development company focusing on serious Central Nervous System (CNS) disorders, announces that the U.S. Food and Drug Administration (FDA) has awarded Orphan Drug designation for MCD-386CR, its lead drug candidate, for the treatment of Progressive Supranuclear Palsy (PSP).

Orphan status entitles Mithridion to seven years of market exclusivity upon approval of MCD-386 for treating PSP, and to apply for grant funding to contribute to clinical trial costs, tax credits, and a waiver of certain FDA fees.  Orphan status is intended to encourage the development of drugs for diseases affecting fewer than 200,000 persons in the USA.

PSP is a progressive brain disease in which neurons degenerate in regions of the brain vital for eye movements, balance, walking, speech, and cognition.  Cognitive impairment typically involves slowed thinking, and difficulties with reasoning, planning, and shifting between tasks, caused by dysfunction of the brain's executive functions.  This has been called "dysexecutive  syndrome."

"Orphan status will help us immeasurably to bring together the resources and support needed to evaluate MCD-386CR in this rare but important disease, and indeed in other devastating brain diseases for which there are no current therapies," said Trevor M. Twose, Ph.D., the company's Chief Executive. "Based on results in preclinical studies, we believe MCD-386CR potentially will help restore cognition, so vital to human functioning, and potentially could treat the underlying processes causing the degeneration of neurons in PSP."

As a part of its recently-articulated strategy, Mithridion is actively exploring opportunities to develop its drug candidates in niche market opportunities in serious CNS or brain disorders, in addition to more common diseases, such as Alzheimer's disease and schizophrenia.  Several promisi
'/>"/>

SOURCE Mithridion, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. US FDA Grants Orphan Drug Status to Immtechs Pafuramidine for Treatment of African Sleeping Sickness
2. Chinese SFDA Grants Immtech Fast Track Status
3. Ethics Group Asks USAID Inspector General to Investigate Legality of Grants to Soros Groups
4. NTMir Announces Research Grants for Epidemiology and Household Water as Source of Infection
5. FDA Grants Approval to Extend U.S. Enrollment and Clinical Trial
6. FDA Grants Priority Review for Daiichi Sankyo, Lilly Drug, prasugrel
7. FDA Grants Priority Review for ACIPHEX(R) (rabeprazole sodium) sNDA for Short-Term Treatment of GERD in Adolescents
8. FDA Grants Priority Review for PROMACTA(R) (eltrombopag)
9. FDA Grants NeoVistas Request to Expand CABERNET Trial to 30 Sites in the U.S.
10. FDA Grants Market Clearance for the LipiScan(TM) Coronary Imaging System Developed by InfraReDx, Inc. - A Novel Spectroscopy System for the Identification of Lipid Core Containing Plaques of Interest in the Coronary Arteries
11. FDA Grants Pediatric Exclusivity for TOPAMAX(R), Extending the Marketing Exclusivity by Six Months
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... , Sept. 16, 2014  Formex, LLC ... announced that Mr. Greg Weilersbacher joined Formex as ... 2014. Greg Weilersbacher ... with focused expertise in Quality Assurance, Facility ... Mr. Weilersbacher brings to Formex a diverse ...
(Date:9/16/2014)... 2014   HemCon Medical Technologies, Inc. ... Wellness Solutions(R), Inc. (OTCQB: TWSI) and a ... announced today that the revenue performance on their ... and microdispersed oxidized cellulose raw material is up ... expects third quarter revenues to surpass the prior ...
(Date:9/16/2014)... ORLANDO, Fla. , Sept. 16, 2014   ... standard in the patient experience at hospitals. The myComfort™ ... , Vestagen,s active barrier fabric that is fluid repellant, ... shown to inhibit the growth of bacteria on the ... the role clothing plays in the chain of transmission. ...
Breaking Medicine Technology:Greg Weilersbacher Joins Formex, LLC As Director of Quality Assurance and Quality Control 2HemCon Medical Technologies, Inc. Projects Strong Third Quarter Revenues 2HemCon Medical Technologies, Inc. Projects Strong Third Quarter Revenues 3HemCon Medical Technologies, Inc. Projects Strong Third Quarter Revenues 4New Vestagen Patient Garments Aim to Minimize Pathogen Transmission Inside Hospitals 2
... THOR ), a world leader in device-based mechanical circulatory ... today that revenues for the first quarter of 2012 were ... million in the same period a year ago.  ... net income on a GAAP basis of $25.5 million, or ...
... funded by The Michael J. Fox Foundation (MJFF) have identified ... treat dyskinesia, the debilitating, uncontrollable movements that are often a ... dyskinesia a top research priority due to its significant negative ... findings, from a team of researchers at eight sites across ...
Cached Medicine Technology:Thoratec Reports First Quarter 2012 Results 2Thoratec Reports First Quarter 2012 Results 3Thoratec Reports First Quarter 2012 Results 4Thoratec Reports First Quarter 2012 Results 5Thoratec Reports First Quarter 2012 Results 6Thoratec Reports First Quarter 2012 Results 7Thoratec Reports First Quarter 2012 Results 8Thoratec Reports First Quarter 2012 Results 9Thoratec Reports First Quarter 2012 Results 10Thoratec Reports First Quarter 2012 Results 11Thoratec Reports First Quarter 2012 Results 12Thoratec Reports First Quarter 2012 Results 13Thoratec Reports First Quarter 2012 Results 14Michael J. Fox Foundation-Funded Study Identifies Best Dyskinesia Clinical Rating Scale 2Michael J. Fox Foundation-Funded Study Identifies Best Dyskinesia Clinical Rating Scale 3Michael J. Fox Foundation-Funded Study Identifies Best Dyskinesia Clinical Rating Scale 4
(Date:9/17/2014)... 17, 2014 MicroSourcing International, Inc., an ... Outsourcing (BPO) services in the Philippines, announced today that ... Vice President – North America to further develop their ... a 15 year veteran of the offshore outsourcing industry ... companies, ranging in size from small businesses to Fortune ...
(Date:9/17/2014)... FL (PRWEB) September 17, 2014 Luxury ... pleased to announce their newest addition to the Regenepure ... conditioner is formulated with nourishing and beneficial ingredients including ... to provide hair with ample moisture, while also encouraging ... Conditioner is formulated to complement the Regenepure DR ...
(Date:9/16/2014)... 2014 Recently, BamboofloorChina.com, the popular online ... assortment of strand woven bamboo floors to ... a big promotion for the new items; the current ... Autumn is a great shopping season. Therefore, BamboofloorChina.com spares ... and new customers. All practical items offered by BamboofloorChina.com ...
(Date:9/16/2014)... September 17, 2014 Marybeth Cale, owner of ... miles north of Manhattan in the small village of Rhinebeck, ... to the business. Cale, a mompreneur, has expanded the business ... and inspire people to maximize potential. Those services will include ... well as one-on-one life coaching for clients all over the ...
(Date:9/16/2014)... Los Angeles, CA (PRWEB) September 17, 2014 ... should suffer or die because of a facial deformity.” To ... be held on September 19, 2014, at the Beverly Wilshire ... more than 220,000 young people worldwide whose lives have been ... are so excited to be involved with Operation Smile,” said ...
Breaking Medicine News(10 mins):Health News:MicroSourcing Appoints New Senior Vice President of North America 2Health News:Luxury Barber Adds New Regenepure Biotin Conditioner to Their Selection of Grooming Products 2Health News:BamboofloorChina.com Announces Its Promotion For Strand Woven Bamboo Floors 2Health News:Mompreneur Marybeth Cale of Cale Communications Announces Launch Of Life Coaching And Workshop Business 2Health News:James & Paula Coburn Foundation to Host the 2014 Smile Gala, Presented by Operation Smile 2
... quit, particularly for some teens and African-Americans, who have ... by a team of researchers. , Recent studies have ... have a lower quit rate than comparable smokers of ... suggested in the report is that the menthol effect ...
... ARBOR, Mich. Black people with early stage liver cancer ... disease, according to a new study from the University of ... percent of white liver cancer patients were alive but only ... patients were. Median survival times ranged from 10 months for ...
... surgery for upper airway and digestive track malignant tumors ... based on patient function and survival, according to University ... squamous cell carcinomas account for about 4 percent of ... Currently the standard minimally invasive surgery for these tumors ...
... Reporter , MONDAY, Dec. 20 (HealthDay News) -- Most trauma ... make it to their final destination within the two hours ... patients did make it within the time window, ... study in the December issue of the Archives of ...
... By Steven Reinberg HealthDay Reporter , MONDAY, Dec. ... Americans, a new study shows, despite reported links to an ... "spray-on" tans. In fact, about one in every five ... use indoor tanning, University of Minnesota researchers report. "Tanning ...
... -- Most head and neck cancer patients can speak ... but several factors may be associated with poor outcomes, ... who were assessed nearly three years after they were ... cancer. The U.S. researchers gave a speaking score ...
Cached Medicine News:Health News:Quitting menthol cigarettes may be harder for some smokers 2Health News:Blacks with liver cancer more likely to die, study finds 2Health News:Robotic surgery for head and neck cancer shows promise 2Health News:Most Trauma Patients Not Transferred Within Mandated Time Frame in Illinois 2Health News:Most Trauma Patients Not Transferred Within Mandated Time Frame in Illinois 3Health News: Tanning Beds Still Popular Despite Skin Cancer Risk 2Health News: Tanning Beds Still Popular Despite Skin Cancer Risk 3Health News:Speech, Swallowing Usually OK After Head & Neck Cancer Therapy 2
... SmartCycler System is a rapid, real-time thermal ... biological samples. By automating much of the ... individually programmable, it is the fastest, easiest ... on the market. The SmartCycler delivers highly ...
Chemically Resistant Sealing Mat for 96ch, 1.1ml or 2.0ml, Deep Well, Round Available Sterile...
Sealing Mat for 96-well PCR Plate, Natural...
MicroAmp Full Plate Covers, which are manufactured from PCR-compatible rubber, are non-sterile, autoclavable and guaranteed reusable up to five times....
Medicine Products: