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FDA Grants Full Approval for PROMACTA® (eltrombopag) for Treatment of Rare Blood Disorder
Date:2/25/2011

e of thrombocytopenia and hemorrhage risk after PROMACTA cessation, hematologic malignancies and progression of malignancies, and cataracts, PROMACTA is available only through a restricted distribution program called PROMACTA CARES.

Additional PROMACTA Information

PROMACTA is an oral, non-peptide thrombopoietin receptor agonist that has been shown in pre-clinical and clinical research to stimulate the proliferation and differentiation of megakaryocytes, the bone marrow cells that give rise to blood platelets.  PROMACTA was discovered as a result of a research collaboration between GlaxoSmithKline and Ligand Pharmaceuticals (Nasdaq: LGND). It was developed by GlaxoSmithKline.

Note to Editors

PROMACTA® is a registered trademark of the GlaxoSmithKline group of companies.

To access the latest GSK news, visit http://us.gsk.com/.

GlaxoSmithKline – one of the world's leading research-based pharmaceutical and healthcare companies – is committed to improving the quality of human life by enabling people to do more, feel better and live longer.  For further information go to us.gsk.com, follow us on twitter.com/GSKUS or visit our blog (www.morethanmedicine.us.gsk.com/blog/).

Cautionary statement regarding forward-looking statements

Under the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995, GSK cautions investors that any forward-looking statements or projections made by GSK, including those made in this announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Factors that may affect GSK' s operations are described under 'Risk Factors' in the 'B
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SOURCE GlaxoSmithKline
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