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FDA Grants Cequent IND - Clears Way for First-Ever Clinical Trial of Orally Delivered RNAi Therapeutic: CEQ508, a tkRNAi Drug Candidate in Oncology
Date:12/10/2009

cs for such rare, underserved diseases are often allowed to enroll patients as opposed to healthy volunteers, potentially accelerating the timeline to develop approved products.

Financing update

In October 2009, Cequent announced that it had initiated a Series B round of financing, seeking to raise $15 million to take the company through Phase II clinical trials with its lead drug candidate. In November 2009, it closed on $3.35 million in first-tranche equity financing from existing investors.

About Cequent Pharmaceuticals, Inc. (www.cequentpharma.com)

An early-stage biopharmaceutical company, Cequent is pioneering the development of novel therapeutics to prevent and treat a wide range of human disorders - from inflammatory disease to cancer - based on the company's proprietary technology, TransKingdom RNA interference (tkRNAi). Cequent's first products, now entering clinical development, are orally administered drug candidates targeting colon-cancer prevention and inflammatory bowel disease. The company designed its powerful tkRNAi technology as a therapeutic to deactivate specific disease-causing genes safely and effectively, using non-pathogenic bacteria as an engine to produce and deliver RNAi directly into cells. It is based on ground-breaking scientific research originating at the Institut Pasteur (Paris, France) and at the Beth Israel Deaconess Medical Center/Harvard Medical School. A privately held company based in Cambridge, Massachusetts, Cequent was established in 2006.

*A video of the NIH RAC hearing is available at http://videocast.nih.gov/ram/rac090909.ram . The Cequent presentation begins at approximately 2:58 on the video.

SOURCE Cequent Pharmaceuticals, Inc.


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SOURCE Cequent Pharmaceuticals, Inc.
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