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FDA Clears Hologic's Single Energy Femur Exam to Visualize Features Associated with Developing Atypical Femur Fractures on a DXA Platform
Date:8/1/2013

rt poorer health and function after the fracture.1 By including a convenient way for the physician to assess possible developing AFFs, early medical intervention may avoid the significant morbidity of a complete atypical femur fracture."

"The 2010 American Society for Bone and Mineral Research (ASBMR) Task Force on atypical femoral fracture emphasized that physicians should ask patients on bisphosphonates about thigh or groin pain, as this often precedes atypical femur fractures," comments Kevin Wilson, PhD, Hologic Scientific Director of Skeletal Health.2 "Further, the FDA has instructed physicians to evaluate any patients on bisphosphonates with thigh or groin pain to rule out a femoral fracture.3 Our SE Femur Exam is cleared by the FDA to visualize features associated with AFFs, and this can be done quickly and conveniently at the time of osteoporosis assessment."

About Atypical Femur Fractures:Patients suffering from osteoporosis are often treated with bisphosphonates to prevent or slow the loss of bone mass. Since their approval in 1995, bisphosphonates have become one of the most popular treatment options for the prevention of common osteoporosis-related fractures, primarily in post-menopausal women. Recently, studies have linked long-term bisphosphonate therapy with increased risk of atypical femur fractures.

Patients with atypical femur fractures frequently report having groin or thigh pain prior to being diagnosed with the fracture. These fractures are often bilateral and appear to evolve over time with initial development of a cortical bump that likely represents early periosteal thickening of the femoral shaft which is the result of the formation of new bone in response to injury or other stimuli. In addition, a transverse cortical lucency, or thin black line, may be present in the region of the periosteal thickening and indicates an incomplete fracture. This may or may not
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SOURCE Hologic, Inc.
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