Navigation Links
FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent
Date:7/20/2009

approvals of Tekturna HCT were based on a clinical trial program involving over 6,200 patients and evaluated more than 2,700 patients exposed to combinations of Tekturna and hydrochlorothiazide. The safety and efficacy of Tekturna HCT were evaluated in patients with mild-to-moderate hypertension in an 8-week, randomized, double-blind, placebo-controlled, parallel-group, 15-arm factorial trial (n=2762). Patients were randomized to receive various combinations of Tekturna (75 mg to 300 mg) plus hydrochlorothiazide (6.25 mg to 25 mg) once daily (without titrating up from monotherapy) and followed for blood pressure response. The combination of Tekturna and hydrochlorothiazide resulted in additive placebo-adjusted decreases in systolic and diastolic blood pressure at trough of 10-14/5-7 mmHg at doses of 150-300 mg/12.5-25 mg, compared to 5-8/2-3 mmHg for Tekturna 150 mg to 300 mg and 6-7/2-3 mmHg for hydrochlorothiazide 12.5 mg to 25 mg alone. Blood pressure reductions with the combinations were greater than the reductions with the monotherapies. The safety and efficacy of Tekturna HCT as initial therapy was evaluated in this trial. All patients randomized to the combination groups received the combination treatment of Tekturna HCT at assigned doses as initial therapy without titration from monotherapy. The antihypertensive effect of Tekturna HCT were largely manifested within 1 week. The maximum antihypertensive effect was generally attained after about 4 weeks of therapy.

About Tekturna and Tekturna HCT

TEKTURNA and TEKTURNA HCT are prescription medications for adults used to treat high blood pressure. TEKTURNA and TEKTURNA HCT may be used alone or in combination with other high blood pressure medications. It is not known whether additive effects are present when TEKTURNA or TEKTURNA HCT are used in combination with types of medications called ACE inhibitors or beta-blockers. TEKTURNA HCT can be used first if your doc
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. FDA Approves Lillys Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women
2. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
3. FDA Approves Cymbalta(R) for Maintenance Treatment of Major Depressive Disorder
4. European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection
5. FDA Approves MiddleBrooks Amoxicillin PULSYS for Pharyngitis/Tonsillitis in Adolescents and Adults
6. FDA Approves XYZAL(R) (levocetirizine dihydrochloride) Oral Solution for the Relief of Seasonal and Year Round Allergies and Chronic Idiopathic Urticaria
7. UM Maryland Industrial Partnerships Program Approves 18 Collaborative Research Projects, Worth $4.4 Million, Between University Faculty, State Technology Companies
8. U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)
9. U.S. Food and Drug Administration Approves ORENCIA(R) (abatacept) for the Treatment of Moderate-to-Severe Polyarticular Juvenile Idiopathic Arthritis (JIA) in Patients Six Years and Older
10. FDA Approves HIFU Clinical Trial for Recurrent Prostate Cancer
11. EPA Approves XDS-CALUX(R) as Alternate Dioxin Test Method 4435
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... N.C. , April 17, 2015 ... the Integrated Embolic Protection™ filter platform for angioplasty ... of a $5.6 million Series B financing round ... venture firm with a focus on medical devices, ... The round also included Mountain Group Partners, Lookout ...
(Date:4/17/2015)... CHICAGO, Ill. , April 17, 2015  AbbVie Inc. ... today announced that it has extended the expiration of its ... common stock of Pharmacyclics, Inc. to 5 p.m., ... On April 17, 2015, AbbVie also voluntarily ... Antitrust Improvements Act in order to provide the FTC with ...
(Date:4/17/2015)... April 17, 2015 Inivata, a ... today that their presence at the 2015 American Association for ... by co-founder Nitzan Rosenfeld and a poster presentation. ... 18 th - 22 nd . The ... ctDNA , forms part of a session on ...
Breaking Medicine Technology:Contego Medical Closes $5.6 Million in Series B Funding 2Contego Medical Closes $5.6 Million in Series B Funding 3AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 2AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 3AbbVie Extends Exchange Offer to Acquire Pharmacyclics, Inc. 4Inivata Co-founder Nitzan Rosenfeld to Present at AACR Annual Meeting 2
... survival advantage ... standard therapy, -- First study to show survival advantage ... Pharmion Corporation,(Nasdaq: PHRM ) today announced that the ... approval of Thalidomide,Pharmion(R) for use in combination with melphalan and ...
... Appoints U.S. Biotest to Oversee Trials, PRINCETON, ... Board: DSCI), a provider of advanced wound care ... services agreement with San,Luis Obispo-based, privately held U.S. ... of DSC127, a novel and rapid wound-healing and,scar-reduction ...
Cached Medicine Technology:Thalidomide Pharmion(R) Receives Positive Opinion for Treatment of First-line Multiple Myeloma from European Medicines Agency 2Thalidomide Pharmion(R) Receives Positive Opinion for Treatment of First-line Multiple Myeloma from European Medicines Agency 3Thalidomide Pharmion(R) Receives Positive Opinion for Treatment of First-line Multiple Myeloma from European Medicines Agency 4Thalidomide Pharmion(R) Receives Positive Opinion for Treatment of First-line Multiple Myeloma from European Medicines Agency 5Thalidomide Pharmion(R) Receives Positive Opinion for Treatment of First-line Multiple Myeloma from European Medicines Agency 6Derma Sciences to Enter Phase II Development of Wound Healing Product That May Use Body's Own Naturally Occurring Stem Cells 2Derma Sciences to Enter Phase II Development of Wound Healing Product That May Use Body's Own Naturally Occurring Stem Cells 3Derma Sciences to Enter Phase II Development of Wound Healing Product That May Use Body's Own Naturally Occurring Stem Cells 4
(Date:4/17/2015)... April 17, 2015 Alcohol and Violence ... (NCADD) notes that drinking and driving has been the ... the same time, the link between alcohol and crime ... abuse and violence and sexual assault, and their relationship ... the NCADD, 5.3 million adults in America were drinking ...
(Date:4/17/2015)... Sulphur Springs, Texas (PRWEB) April 17, 2015 ... (TLW) four years ago, the Texas non-profit organization has empowered ... part of its effort to bring fresh water and ... recently partnered with Liberty University. Between March 17 and 27, ... which will provide 7,000 Liberians with fresh water and the ...
(Date:4/17/2015)... Washington, DC (PRWEB) April 17, 2015 ... the HHT Diagnoses and Treatment Act HR 1849 in ... improve diagnosis rates and treatment for patients with the ... introduced in the past, would be the first to ... diagnoses and appropriate treatment of hereditary hemorrhagic telangiectasia. This ...
(Date:4/17/2015)... California (PRWEB) April 17, 2015 At ... Entertainment’s EcoLuxe Lounge and the “Salute to the Oscars” ... luxurious Beverly Hilton Hotel, overlooking the impressive Los Angeles ... were organized by Debbie Durkin, LA’s leading producer of ... Showcasing many of the world’s premier providers of eco-friendly ...
(Date:4/17/2015)... Baptist Health and The University of Texas ... designed to transform oncology care in northeast Florida and ... create a joint cancer program to enhance patient access ... MD Anderson Cancer Center is anticipated to open in ... highly coordinated, multidisciplinary cancer care for adults in the ...
Breaking Medicine News(10 mins):Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 3Health News:The Last Well and Liberty U’s TEN Initiative raises $21,000 to Bring Fresh Water & The Gospel to 7,000 Liberians 2Health News:House Representatives Introduce Bill to Fight Genetic Disease 2Health News:Choices Recovery Speaks with Dakota Hood of “The Hunger Games” about Addiction in Hollywood 2Health News:Baptist Health and MD Anderson Finalize Agreement to Transform Cancer Care in Region 2Health News:Baptist Health and MD Anderson Finalize Agreement to Transform Cancer Care in Region 3
... MYL ),today announced that Mylan Pharmaceuticals Inc. has ... (FDA) for its Abbreviated New,Drug Application (ANDA) for Cetirizine ... HCl Tablets are the generic version of Pfizer,s Zyrtec(R),Tablets, ... the 12,months ending Sept. 30, 2007., This product ...
... 28, 2007 Laser surgery to correct vision problems ... Keratotomy (PRK) is typically used to correct low to ... for high myopia corrections. Although over 18 million LASIK ... controversy regarding the maximum correction possible and efficacy with ...
... patients than are other doctors, study finds , , THURSDAY, ... of spirituality and faith when interacting with patients, but ... finds. , In fact, more than 90 percent of ... ask patients about their religious faith or spirituality, while ...
... 27 The National Drug,Intelligence Center (NDIC), ... and,the nation,s principal center for strategic drug ... Assessment. This strategic,assessment presents an analysis of ... distribution, and abuse in the,United States. The ...
... Dec. 27 Like a lot of Americans, ... healthier your New Year,s resolution -- but,it,s important ... off by January,2nd., Listen to this report ... can access video, audio, text, graphics and,photos for ...
... Practice in Hudson is the Only Accredited Lab in Summit County ... ... Dec. 27 Western Reserve Heart Care, a,cardiology testing and treatment ... echocardiography lab by the,Intersocietal Commission for the Accreditation of Echocardiography,Laboratories (ICAEL)., ...
Cached Medicine News:Health News:LASIK works well, according to long-term study of highly myopic patients 2Health News:Most Psychiatrists Open to Discussing Spiritual Concerns 2Health News:Most Psychiatrists Open to Discussing Spiritual Concerns 3Health News:National Drug Intelligence Center Releases 2008 National Methamphetamine Threat Assessment 2Health News:Western Reserve Heart Care Receives ICAEL Echocardiography Accreditation 2
Biopro rimmed acetabular is manufactured from titanium and is porous coated on the outside of its shell. The rimmed acetabular accommodates a polyethylene inert....
The Plasmacup SC satisfies two important requirements: high primary stability and a low friction bearing surface....
The cementless acetabular shells form part of the Mallory head range of femoral and acetabular implants....
Trident Hemispherical Acetabular Shells are a true hemispherical shape designed to achieve press-fit fixation by under-reaming the acetabulum....
Medicine Products: