Navigation Links
FDA Approves Tekturna HCT(R) as Initial Treatment in Patients Unlikely to Achieve Their Blood Pressure Goals With a Single Agent
Date:7/20/2009

approvals of Tekturna HCT were based on a clinical trial program involving over 6,200 patients and evaluated more than 2,700 patients exposed to combinations of Tekturna and hydrochlorothiazide. The safety and efficacy of Tekturna HCT were evaluated in patients with mild-to-moderate hypertension in an 8-week, randomized, double-blind, placebo-controlled, parallel-group, 15-arm factorial trial (n=2762). Patients were randomized to receive various combinations of Tekturna (75 mg to 300 mg) plus hydrochlorothiazide (6.25 mg to 25 mg) once daily (without titrating up from monotherapy) and followed for blood pressure response. The combination of Tekturna and hydrochlorothiazide resulted in additive placebo-adjusted decreases in systolic and diastolic blood pressure at trough of 10-14/5-7 mmHg at doses of 150-300 mg/12.5-25 mg, compared to 5-8/2-3 mmHg for Tekturna 150 mg to 300 mg and 6-7/2-3 mmHg for hydrochlorothiazide 12.5 mg to 25 mg alone. Blood pressure reductions with the combinations were greater than the reductions with the monotherapies. The safety and efficacy of Tekturna HCT as initial therapy was evaluated in this trial. All patients randomized to the combination groups received the combination treatment of Tekturna HCT at assigned doses as initial therapy without titration from monotherapy. The antihypertensive effect of Tekturna HCT were largely manifested within 1 week. The maximum antihypertensive effect was generally attained after about 4 weeks of therapy.

About Tekturna and Tekturna HCT

TEKTURNA and TEKTURNA HCT are prescription medications for adults used to treat high blood pressure. TEKTURNA and TEKTURNA HCT may be used alone or in combination with other high blood pressure medications. It is not known whether additive effects are present when TEKTURNA or TEKTURNA HCT are used in combination with types of medications called ACE inhibitors or beta-blockers. TEKTURNA HCT can be used first if your doc
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. FDA Approves Lillys Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women
2. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
3. FDA Approves Cymbalta(R) for Maintenance Treatment of Major Depressive Disorder
4. European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection
5. FDA Approves MiddleBrooks Amoxicillin PULSYS for Pharyngitis/Tonsillitis in Adolescents and Adults
6. FDA Approves XYZAL(R) (levocetirizine dihydrochloride) Oral Solution for the Relief of Seasonal and Year Round Allergies and Chronic Idiopathic Urticaria
7. UM Maryland Industrial Partnerships Program Approves 18 Collaborative Research Projects, Worth $4.4 Million, Between University Faculty, State Technology Companies
8. U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)
9. U.S. Food and Drug Administration Approves ORENCIA(R) (abatacept) for the Treatment of Moderate-to-Severe Polyarticular Juvenile Idiopathic Arthritis (JIA) in Patients Six Years and Older
10. FDA Approves HIFU Clinical Trial for Recurrent Prostate Cancer
11. EPA Approves XDS-CALUX(R) as Alternate Dioxin Test Method 4435
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... 28, 2015 Research ... of the "Investigation Report on China,s Insulin ... Developed by Novo Nordisk, insulin aspart ... important drug for the treatment of diabetes. Compared ... acting insulin analog, starts working fast and reports ...
(Date:8/28/2015)... 28, 2015  IP Shakti, LLC, today announced that it ... Logo - http://photos.prnewswire.com/prnh/20150827/261551LOGO ... new corporate identity signifies our transformation into a company focused ... platform for patent claim validity." ... proprietary AIA Shield™ platform, the Company commenced a corporate re-branding ...
(Date:8/28/2015)... and PITTSBURGH , ... MYL ) today announced that its shareholders have ... (NYSE: PRGO ; TASE) and the related ... at an extraordinary general meeting of shareholders held ... votes cast at the extraordinary general meeting. In ...
Breaking Medicine Technology:China Insulin Aspart Market Report 2010-2019 - Developed by Novo Nordisk 2IP Shakti, LLC Changes Company Name to Prediqtus, LLC 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9
... 8, 2011 Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ... Extension Study presented at ESCWhen: , Monday, September 12, 2011 ... , Live on the Internet.  Simply log onto our Web ... the live event, a replay of the webcast will be ...
... 8, 2011 Anthera Pharmaceuticals, Inc. (Nasdaq: ... to treat serious diseases associated with inflammation, today ... has given the Company a Notice of Allowance ... of cardiovascular disease and dyslipidemia using secretory phospholipase ...
Cached Medicine Technology:Anthera Pharmaceuticals Announces Notice of Allowance of U.S. Patent Application Covering A-002 Plus Statin Compositions 2Anthera Pharmaceuticals Announces Notice of Allowance of U.S. Patent Application Covering A-002 Plus Statin Compositions 3
(Date:8/28/2015)... ... ... For Dallas, the time is nearing for the annual Heart Walk, and North ... American Heart Association hosts their well-known Heart Walk to raise money in awareness and ... be made. Walkers can participate in the cause and someone can also donate, even ...
(Date:8/28/2015)... ... 28, 2015 , ... As reported by Medical Daily on August 22 ... results that last for two years, the longest of any cellulite reduction system currently ... for a long-lasting, effective solution for their cellulite, according to Dr. Robert Weiss, director ...
(Date:8/28/2015)... Manistee, Michigan (PRWEB) , ... August 28, 2015 , ... ... in Western Michigan, joined as sponsor of the “Music With A Mission” benefit concert ... purpose behind the event was to raise money to support music education programs in ...
(Date:8/28/2015)... ... , ... Saint Petersburg, FL —Pocket Protein™, a protein beverage ... gluten, lactose or caffeine in a convenient 2 oz. pouch that never needs ... Awards. , Five consumer packaged goods (CPG) products were selected by the SupplySide ...
(Date:8/28/2015)... ... , ... Altima Technologies, Inc., the maker of popular NetZoom™ ... and audio-video devices, recently released Visio Stencils for the following product lines: ... VNX Series , Super Micro Computer SuperStorage, Hitachi Data Systems Virtual Storage Series, ...
Breaking Medicine News(10 mins):Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 3Health News:New Video Released on "Music With A Mission" Benefit Concert Headlining Artist Cadillac Three & Best Drug Rehabilitation 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 3
... cell research, experts say , , MONDAY, Nov. 3 (HealthDay ... mice from mouse bodies that had been frozen for ... raise the specter of resurrecting lost species a la ... said recreating woolly mammoths was "probably impossible." , ...
... study conducted by researchers at Georgia State University is ... of preemptive morphine prior to a painful procedure in ... adult rodents. These studies have serious implications for ... prior to surgery. Infant rodents that did not receive ...
... efforts to educate the public about HIV, a new ... University and Children,s Hospital Boston has found that two-thirds ... spreading HIV in the home. , The qualitative study ... minor children, in families with an HIV-infected parent about ...
... at the University of California, San Diego (UCSD) are ... revving up the immune system to combat a particularly ... is being offered to patients with chronic lymphocytic leukemia ... to initial treatment or harbors a particular chromosomal abnormality ...
... which claimed that homeopathy is just a placebo, published in ... George Lewith, Professor of Health Research at Southampton University comments: ... nor of the various vital assumptions made about the data. ... homeopathy works for some conditions but not others, or change ...
... increases 32% to $16.0 million. - Heart valve therapy products revenue rises 39.1% ... surgical ablation products revenue grows 21.7%. - Third quarter gross profit ... 2008 revenue guidance to $65 - $66 ... million., MINNEAPOLIS, Nov. ...
Cached Medicine News:Health News:Scientists Make Clones of Mice Dead 16 Years 2Health News:GSU study first to confirm long-term benefits of morphine treatment in infants 2Health News:Study finds fears of HIV transmission in families with infected parent 2Health News:Moores UCSD Cancer Center studying novel leukemia vaccine for high-risk patients 2Health News:New evidence for homeopathy 2Health News:ATS Medical Announces Third Quarter Results 2Health News:ATS Medical Announces Third Quarter Results 3Health News:ATS Medical Announces Third Quarter Results 4Health News:ATS Medical Announces Third Quarter Results 5Health News:ATS Medical Announces Third Quarter Results 6Health News:ATS Medical Announces Third Quarter Results 7Health News:ATS Medical Announces Third Quarter Results 8
Thermometer for Round Water Bath...
... The F340 is a basic laboratory system ... pH results can be obtained when used ... 3-in-1 electrode. • Fast and easy one ... recognition for five buffers (pH 1.68, 4.00, ...
... - the multifunctional high-end microplate reader with ... detection modes., Fluorescence Intensity - FRET ... - HTRF, AlphaScreen , Luminescence ... dual emission microplate reader with fastest read ...
GENios Pro, TECANs advanced, multi-functional injector reader offers simultaneous reagent dispensing and detection for monitoring of fast kinetic reactions...
Medicine Products: