Navigation Links
FDA Approves Picato® (ingenol mebutate) Gel, the First and Only Topical Actinic Keratosis (AK) Therapy With 2 or 3 Consecutive Days of Once-Daily Dosing
Date:1/25/2012

eratosis on the face and scalp saw 75 percent or greater reduction of existing AKs (versus 7-8 percent with placebo), while 44-55 percent of patients with AKs on the trunk and extremities experienced 75 percent or more reduction (versus 7 percent reduction for placebo). Patients treated with Picato® gel saw 37-47 percent complete clearance of lesions on the face and scalp, and 28-42 percent on the trunk and extremities, versus up to 5 percent complete clearance with placebo in all studies. Local skin responses (LSRs) on the face and scalp were observed to peak around day 4 and resolve by day 15 in the majority of patients. LSRs on the trunk and extremities peaked around day 8 and markedly improved by day 29.

The most common adverse events were LSRs and included erythema, flaking/scaling, crusting and swelling. Other AEs occurring in ≥ 2 percent of subjects treated with Picato® gel include pain, pruritus and infection at the application site, as well as periorbital edema and headache.

IMPORTANT SAFETY INFORMATION
For topical use only; not for oral, ophthalmic, or intravaginal use. Eye disorders, including severe eye pain, eyelid edema, eyelid ptosis, periorbital edema can occur after exposure. Patients should wash hands well after applying Picato® gel, and avoid transfer of the drug to the periocular area during and after application. Severe skin reactions in the treated area, including erythema, crusting, swelling, vesiculation/pustulation, and erosion/ulceration, can occur after application. Administration of Picato® gel is not recommended until the skin is healed from any previous drug or surgical treatment. The most common adverse reactions observed in clinical trials (greater than or equal to 2%) are local skin reactions, application site pain, application site pruritus, application site irritation, application site infection, periorbital edema, nasopharyngitis and headache. There are no adequate an
'/>"/>

SOURCE LEO Pharma Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. FDA Approves Lillys Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women
2. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
3. FDA Approves Cymbalta(R) for Maintenance Treatment of Major Depressive Disorder
4. European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection
5. FDA Approves MiddleBrooks Amoxicillin PULSYS for Pharyngitis/Tonsillitis in Adolescents and Adults
6. FDA Approves XYZAL(R) (levocetirizine dihydrochloride) Oral Solution for the Relief of Seasonal and Year Round Allergies and Chronic Idiopathic Urticaria
7. UM Maryland Industrial Partnerships Program Approves 18 Collaborative Research Projects, Worth $4.4 Million, Between University Faculty, State Technology Companies
8. U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)
9. U.S. Food and Drug Administration Approves ORENCIA(R) (abatacept) for the Treatment of Moderate-to-Severe Polyarticular Juvenile Idiopathic Arthritis (JIA) in Patients Six Years and Older
10. FDA Approves HIFU Clinical Trial for Recurrent Prostate Cancer
11. EPA Approves XDS-CALUX(R) as Alternate Dioxin Test Method 4435
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... , July 31, 2015 ... decades of experience, the domestic pharmaceutical industry is strong, ... manufacture products to high international standards. One ... known is in sub-Saharan Africa: Morocco has quietly become ... South Africa . Indeed, Moroccan pharma ...
(Date:7/31/2015)... July 31, 2015  Semler Scientific, Inc. (Nasdaq: ... services to healthcare insurers and physician groups, today reported ... 2015. "In the second quarter of ... revenue growth of 54%, quarter over quarter revenue growth ... installed base of FloChec® units of 18%," said Doug ...
(Date:7/31/2015)... MONROVIA, Calif. , July 31, 2015  Xencor, ... developing engineered monoclonal antibodies for the treatment of autoimmune ... the appointment of Yujiro S. Hata to ... of experience in business and corporate development is a ... , Ph.D., president and chief executive officer of Xencor. ...
Breaking Medicine Technology:PharmaBoardroom Releases New Morocco Pharmaceuticals Report 2PharmaBoardroom Releases New Morocco Pharmaceuticals Report 3Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6Xencor Appoints Yujiro S. Hata to Board of Directors 2Xencor Appoints Yujiro S. Hata to Board of Directors 3
(Date:8/1/2015)... Freeport, ME (PRWEB) , ... August 01, 2015 , ... ... “America’s Retail Champions.” , Wilcoxson was given that honor by the National Retail Federation, ... the retail industry. Wilcoxson was one of three Maine business owners to be named ...
(Date:8/1/2015)... ... August 01, 2015 , ... On Tuesday, July 28th, ... who are thought to have been behind the attack on Anthem Inc. which resulted ... zero day exploits, watering hole attacks and spear phishing campaigns. , For ...
(Date:8/1/2015)... ... August 01, 2015 , ... “ reTXT ” was ... the latest and coolest applications on the market for iOS, Android, and Windows. Joe ... with viewers allows users to clarify, edit and delete any message including ones already ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... Ticket Down is a reputable source of ... the MGM Grand Garden Arena. Fans of every genre of music will have an ... 18th, the first day of the festival, the following artists will perform: Sam Smith, ...
(Date:7/31/2015)... ... , ... Super Bowl 50 will emanate from Levi’s Stadium in Santa Clara, CA ... the Super Bowl. In the two weeks that separate the conference championships and the Super ... Super Bowl game will mark the 50th time it has been held and the festivities ...
Breaking Medicine News(10 mins):Health News:Local Retail Advocate Wins National Recognition 2Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 2Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 3Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 4Health News:Correct Auto-Correct and Clarify the Unclear with reTXT Messaging App 2Health News:Cheap 2015 iHeartRadio Music Festival Tickets in Las Vegas at MGM Grand Garden Arena: Ticket Down Slashes Ticket Prices on the iHeart Radio Music Festival in Vegas 2Health News:Cheap 2015 iHeartRadio Music Festival Tickets in Las Vegas at MGM Grand Garden Arena: Ticket Down Slashes Ticket Prices on the iHeart Radio Music Festival in Vegas 3Health News:Cheap 2016 Super Bowl Tickets at Levi's Stadium: Ticket Down Slashes Ticket Prices on Super Bowl 50 Tickets in Santa Clara, CA at Levi's Stadium 2
... HealthDay Reporter , TUESDAY, Nov. 15 (HealthDay News) ... human gene affects how other people see you at first ... The variation might directly influence your personality, especially in terms ... else that affects the way you act. On the other ...
... years of problem drinking, a significant decrease in the function ... This is the system that regulates such functions as impulse ... decrease is seen in men. This is the conclusion of ... the Sahlgrenska Academy at the University of Gothenburg, Sweden. ...
... (HealthDay News) --,Low levels of vitamin D may put women ... one of several new studies on the important nutrient. ... healthy, postmenopausal white women aged 45 to 58, researchers found ... more risk factors for heart disease than 1,225 women with ...
... News) -- People with heart conditions who take vitamins may ... properly, according to a new study. Researchers from the ... irregular heartbeat -- known as atrial fibrillation -- what they ... patients were also asked how well they followed their prescription ...
... Fla. -- Healthy, new heart cells have been generated ... stem cells derived from cardiac biopsies or "cardiospheres," according ... of Medicine and Biomedical Sciences. , The research ... Sessions of the American Heart Association in Orlando. , ...
... develop into any cell type in the body, rely ... metabolic activities. In contrast, mature cells in ... convert sugar and oxygen into carbon dioxide and water ... their metabolic needs. How cells progress from ...
Cached Medicine News:Health News:Does a Gene Make People Seem Kinder? 2Health News:Does a Gene Make People Seem Kinder? 3Health News:Low Vitamin D May Increase Stroke, Heart Attack Risk in Women 2Health News:Heart Patients Using Vitamins May Take Meds Improperly 2Health News:Heart Patients Using Vitamins May Take Meds Improperly 3Health News:New heart cells increase by 30 percent after stem cell infusion 2Health News:UCLA stem cell researchers uncover mechanism that regulates human pluripotent stem cell metabolism 2Health News:UCLA stem cell researchers uncover mechanism that regulates human pluripotent stem cell metabolism 3Health News:UCLA stem cell researchers uncover mechanism that regulates human pluripotent stem cell metabolism 4
300XL System, English (U.K. cord), 100-240 VAC....
Micro-mini fiber optic light....
Micro-mini fiber optic light....
The MC-3 allows for simultaneous use of two lamps, with an additional built-in spare....
Medicine Products: