Navigation Links
FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures
Date:1/29/2010

RESEARCH TRIANGLE PARK, N.C., Jan. 29 /PRNewswire-FirstCall/ -- GlaxoSmithKline (NYSE: GSK) announced today that the U.S. Food and Drug Administration has approved Lamictal®XR™ (lamotrigine) Extended-Release Tablets as once-a-day, add-on therapy for epilepsy in patients ages 13 years and older with primary generalized tonic-clonic seizures.  This is an expanded label, as Lamictal XR is approved for partial onset seizures (with or without secondary generalization) for patients in this age group.

Primary generalized tonic-clonic seizures, known formerly as "grand mal" seizures, are considered the most common form of generalized (affecting both sides of the brain) seizure, occurring in approximately 20 percent of patients with epilepsy.  Patients experiencing a generalized tonic-clonic seizure usually lose consciousness and collapse.  This is followed by muscle stiffening (the tonic phase) and then jerking involving both sides of the body (the clonic phase).  

In a clinical study, the addition of Lamictal XR reduced seizure frequency more than placebo in patients with uncontrolled primary generalized tonic-clonic seizures, when used in adjunctive therapy for patients 13 years of age and older.  The patients in the study were not adequately controlled despite being on one or two anti-epileptic drugs.  

"We were encouraged that the study showed such a significant reduction in the number of primary generalized tonic-clonic seizures in patients who received Lamictal XR in addition to their current regimen.  Over the 19 week treatment period, the median percent reduction in weekly seizure frequency was 75 percent in patients treated with Lamictal XR c
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Chinese State Food and Drug Administration Approves Company Facility for Producing Solid Dosage Perindopril
2. FDA Approves Ampyra to Improve Walking in Adults with Multiple Sclerosis
3. FDA Approves a High Dose Seasonal Influenza Vaccine Specifically Intended for People Ages 65 and Older
4. FDA Approves Lillys ZYPREXA(R) RELPREVV(TM) for Treatment of Schizophrenia in Adults
5. FDA Approves Lillys Zyprexa for Two Adolescent Indications
6. US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder
7. FDA Approves Use of Roche Test to Screen Source Plasma for HIV, Hepatitis B Virus and Hepatitis C Virus
8. FDA Approves ZEGERID OTC(TM) for Over-the-Counter Treatment of Frequent Heartburn
9. FDA Approves Cymbalta(R) for Maintenance Treatment of Generalized Anxiety Disorder
10. FDA Approves Agriflu Seasonal Influenza Vaccine
11. FDA Approves Lysteda to Treat Heavy Menstrual Bleeding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ... (OFT) approval condition to the announced tender offer for all of ... As a result of the waiver, the transaction is no longer ... offer on January 24, 2014 following the currently scheduled expiration time, ...
(Date:1/15/2014)... , January 15, 2014 BreedIT Corp ... exclusive worldwide distributor of highly sophisticated agro-breeding solutions for ... 7, 2014, the Company,s board of directors appointed chemistry ... as its new member of the board. ...
(Date:1/15/2014)...  In an unprecedented effort to curb the spread of "superbugs" such ... vehicles, an advanced and portable UV germicidal lamp manufactured by MRSA-UV ... In order to prevent EMS paramedics and transport ... West Palm Beach Fire Rescue is the first in ...
Breaking Medicine Technology:Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3Superbugs No Longer Ride In Rescue Vehicles 2
... July 12 MedPro Imaging, a leading supplier ... been chosen by the Chicago Bears Football Club, Inc. to ... other health issues for the team during the upcoming 2010 ... Mobile Imaging Services division which offers mobile ultrasound services throughout ...
... July 12 Endo Pharmaceuticals (Nasdaq: ENDP ) today ... offer by its wholly owned subsidiary, HT Acquisition Corp., for all ... HTRN).  American Stock Transfer & Trust Company, the depositary for the ... , New York City time, on July 9, ...
Cached Medicine Technology:MedPro Imaging to Supply Mobile Ultrasound Diagnostics to Chicago Bears Players 2MedPro Imaging to Supply Mobile Ultrasound Diagnostics to Chicago Bears Players 3Endo Pharmaceuticals Announces Expiration of Subsequent Offering Period of Tender Offer for HealthTronics, Inc. 2Endo Pharmaceuticals Announces Expiration of Subsequent Offering Period of Tender Offer for HealthTronics, Inc. 3Endo Pharmaceuticals Announces Expiration of Subsequent Offering Period of Tender Offer for HealthTronics, Inc. 4
(Date:4/17/2014)... Experimental Biology and Medicine a multidisciplinary ... Paul Kenis in the Institute of Genomic Biology ... Illinois Urbana-Champaign describe their recent work on subcellular ... of cell functions including energy metabolism, signaling, and ... regulating normal cellular behavior, redox status has been ...
(Date:4/17/2014)... MD, was recently invited to submit a review ... Microbiology , one of the world,s foremost scientific ... specialist, and chair of the Department of Pediatrics ... analyzed the epidemiology and microbiology of co-infections during ... as more recent 2009 novel H1N1 pandemic. ...
(Date:4/17/2014)... many as 10 million older Americans suffer from depression, ... , However, new research a project that followed ... six years found that Internet use among the ... than 30 percent. , "That,s a very strong effect," ... telecommunication, information studies and media who led the project. ...
(Date:4/17/2014)... Boston University School of Medicine (BUSM) have discovered ... in an experimental model. The findings, reported in ... Abuse , may lead to more effective treatments ... one of the leading causes of illness and ... economic impact by limiting the productivity of workers ...
(Date:4/17/2014)... An international research team led by Cesar A. Arias, ... Center at Houston (UTHealth) has identified a new superbug ... The report appeared in the April 17 issue of ... The new superbug is part of a class of ... or MRSA, which is a major cause of hospital ...
Breaking Medicine News(10 mins):Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:Internet use can help ward off depression among elderly 2Health News:BUSM researchers find anti-seizure drug may reduce alcohol consumption 2Health News:New MRSA superbug emerges in Brazil 2
... Presbyterian Medical Center, high rates of chronic hepatitis B infection ... the New York City area, and most of them do ... considered the standard of care for all persons newly identified ... but one infant was protected from infection in this study, ...
... whose mothers are successfully treated for depression show progressive and ... their moms discontinue treatment, new UT Southwestern Medical Center-led research ... their kids improved and the greater the degree of ... is depressed and don,t even go through the process of ...
... Reporter , MONDAY, May 9 (HealthDay News) -- Among Medicare ... new study finds. But at the same time, a ... may not always be getting the follow-up colonoscopies they need ... which blood is detected in the stool. Both reports ...
... Steven Reinberg HealthDay Reporter , MONDAY, May 9 ... with a lethal nervous system disease known as amyotrophic lateral ... however, that this does not mean people with long ring ... are at higher risk for it. "We have not ...
... By Maureen Salamon HealthDay Reporter , MONDAY, ... concerns, new Korean research suggests that long-term use of ... is linked to an increased risk of fractures. ... 1997 and 2011 found that proton pump inhibitors (PPIs), ...
... , MONDAY, May 9 (HealthDay News) -- People with ... of suffering another attack or dying after even a ... painkillers, including Advil, Motrin or Voltarin, a large ... of almost 84,000 heart attack survivors and found that ...
Cached Medicine News:Health News:Routine antenatal screening for hepatitis B in an urban NYC population 2Health News:Successful depression treatment of mothers has long-term effects on offspring 2Health News:Successful depression treatment of mothers has long-term effects on offspring 3Health News:Study Questions Overuse of Colonoscopy in Medicare Patients 2Health News:Study Questions Overuse of Colonoscopy in Medicare Patients 3Health News:Study Questions Overuse of Colonoscopy in Medicare Patients 4Health News:Ring Finger Length Linked to ALS, Study Suggests 2Health News:Ring Finger Length Linked to ALS, Study Suggests 3Health News:Popular Heartburn Meds May Boost Fracture Risk 2Health News:Popular Heartburn Meds May Boost Fracture Risk 3Health News:After Heart Attack, Certain Painkillers May Raise Risk for Recurrence 2Health News:After Heart Attack, Certain Painkillers May Raise Risk for Recurrence 3
Straight shafts with polished finish. Teeth: 0.12 mm. Tying platform: 5.0 mm. Wide Serrated....
Straight shafts with 0.12 mm teeth and tying platform. Serrated handle with polished finish....
Angled 45 degree shafts with 1 x 2 teeth and 5 mm tying platform. Serrated handle with dull finish....
Heavy curved shafts with 2 x 2 teeth and crisscross serrated 6 mm tying platform. Serrated handle with polished finish....
Medicine Products: