Navigation Links
FDA Approves New Dosage Strength for INTELENCE®
Date:1/3/2011

sitivity reactions develop (including, but not limited to, severe rash or rash accompanied by fever, general malaise, fatigue, muscle or joint aches, blisters, oral lesions, conjunctivitis, facial edema, hepatitis, eosinophilia, angioedema)

  • Monitor clinical status including liver transaminases, and initiate appropriate therapy  
  • Delay in stopping INTELENCE treatment after the onset of severe rash may result in a life-threatening reaction
  • Fat Redistribution: Redistribution and/or accumulation of body fat have been observed in patients receiving antiretroviral (ARV) therapy. The causal relationship, mechanism, and long-term consequences of these events have not been established
  • Immune Reconstitution Syndrome: has been reported in patients treated with ARV therapy, including INTELENCE

    • Use in Specific Populations

  • Hepatic Impairment: INTELENCE should be used with caution in patients with severe hepatic impairment (Child-Pugh Class C) as pharmacokinetics of INTELENCE have not been evaluated in these patients
  • Pregnancy Category B:  INTELENCE should be used during pregnancy only if the potential benefit justifies the potential risk. No adequate and well-controlled studies have been conducted in pregnant women

    • Adverse Reactions

  • The most common adverse drug reactions (> or = 2%) of at least moderate intensity (> or = Grade 2) reported in patients taking INTELENCE and that occurred at a higher rate compared with placebo were rash (10% vs 3%) and peripheral neuropathy (4% vs 2%)

    • Drug Interactions

  • INTELENCE should not be coadministered with the following ARVs: tipranavir/ritonavir, fosamprenavir/ritonavir, atazanavir/ritonavir, full-dose ritonavir (600 mg bid), protease inhibitors administered without low-dose ritonavir, and other NNRTIs
  • INTELENCE should not be co-administered with carbamazepine, phenobarb
    '/>"/>

    • SOURCE Tibotec Therapeutics
    Copyright©2010 PR Newswire.
    All rights reserved

    0

    GOOD

    Page: 1 2 3 4 5

    Related medicine technology :

    1. FDA Approves Lillys Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women
    2. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
    3. FDA Approves Cymbalta(R) for Maintenance Treatment of Major Depressive Disorder
    4. European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection
    5. FDA Approves MiddleBrooks Amoxicillin PULSYS for Pharyngitis/Tonsillitis in Adolescents and Adults
    6. FDA Approves XYZAL(R) (levocetirizine dihydrochloride) Oral Solution for the Relief of Seasonal and Year Round Allergies and Chronic Idiopathic Urticaria
    7. UM Maryland Industrial Partnerships Program Approves 18 Collaborative Research Projects, Worth $4.4 Million, Between University Faculty, State Technology Companies
    8. U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)
    9. U.S. Food and Drug Administration Approves ORENCIA(R) (abatacept) for the Treatment of Moderate-to-Severe Polyarticular Juvenile Idiopathic Arthritis (JIA) in Patients Six Years and Older
    10. FDA Approves HIFU Clinical Trial for Recurrent Prostate Cancer
    11. EPA Approves XDS-CALUX(R) as Alternate Dioxin Test Method 4435
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:5/22/2013)... YORK , May 22, 2013 While ... their teens, friends to drink at home under adult ... about drinking, the truth is that there are serious ... Partnership at Drugfree.org and The Treatment Research ... new, interactive web resource for parents and caregivers to ...
    (Date:5/22/2013)... 2013 PRNewswire – iBio, Inc. (NYSE ... vaccine candidate for the newly emerged H7N9 influenza ... the iBioLaunch™ platform. This validation milestone was achieved ... sequence information to purification of recombinant protein. ... The iBioLaunch platform eliminates the need to ...
    (Date:5/22/2013)... 22, 2013 WomanCare Global recently launched ... an extensive training initiative attended by 90 health ... ) (Logo: http://photos.prnewswire.com/prnh/20101018/DC83896LOGO ) Simplant, ... highly effective subdermal implant composed of two thin, ... (a synthetic form of the hormone progestin). These ...
    Breaking Medicine Technology:Myths Debunked: Underage Drinking of Alcohol at Home Leads to Real Consequences for Both Parents and Teens 2Myths Debunked: Underage Drinking of Alcohol at Home Leads to Real Consequences for Both Parents and Teens 3Myths Debunked: Underage Drinking of Alcohol at Home Leads to Real Consequences for Both Parents and Teens 4Myths Debunked: Underage Drinking of Alcohol at Home Leads to Real Consequences for Both Parents and Teens 5Myths Debunked: Underage Drinking of Alcohol at Home Leads to Real Consequences for Both Parents and Teens 6Myths Debunked: Underage Drinking of Alcohol at Home Leads to Real Consequences for Both Parents and Teens 7iBio Technology Produces Vaccine Candidate for Recently Emerged H7N9 Influenza 2WomanCare Global launches Simplant, Long-acting Reversible Contraception, in Chile 2
    ... SAN DIEGO, Feb. 3, 2011 Neurocrine Biosciences, Inc. (Nasdaq: ... report its fourth quarter and year-end 2010 financial results after ... will then host a live conference call and webcast to ... afternoon, February 10, 2011 at 5:00 p.m. Eastern Time (2:00 ...
    ... 2011 SkinMedica, Inc., the fastest-growing professional skin ... that it is introducing a new, fast-acting anti-redness ... in over two decades.  It is the first ... visible redness.     (Photo: ...
    Cached Medicine Technology:SkinMedica Launches Redness Relief CalmPlex™ 2SkinMedica Launches Redness Relief CalmPlex™ 3
    (Date:5/22/2013)... , , TUESDAY, May 21 (HealthDay News) -- The overall ... in 10 people either overweight or obese and large ... or not exercising, a new government report shows. , ... Control and Prevention, the report found Americans continuing to ... to soaring rates of heart disease, diabetes and other ...
    (Date:5/22/2013)... Teams who focus on productivity, process, quality, ... Do-Done StepTracker whiteboard as a rallying point for project ... display the current status of our company-wide lean initiatives ... is listed down the side and the milestones are ... squares are filled with yellow circles. Turning the magnets ...
    (Date:5/22/2013)... Paris, France: Results from a large observational ... whether bivalirudin is superior to heparin in ... 30-day mortality in patients with non-ST segment ... coronary intervention (PCI)., European and US NSTE-ACS ... alternative to unfractionated heparin plus GP IIb/IIIa ...
    (Date:5/22/2013)... 22, 2013 The PreDiabetes Center ... in the Greater Philadelphia Tour de Cure, a premier cycling ... are passionate about stopping the spread of diabetes , ... , The Tour de Cure will take place Saturday, ... Road in Ambler, 30 minutes outside of Philadelphia, between the ...
    (Date:5/22/2013)... New York City, New York (PRWEB) May 22, 2013 ... Black American: Causes, Culture, Consequences, and Cost ” article published ... on obesity is fully justified. The Centers for Disease ... of U.S. adults aged 20 and over are overweight, 35.7% ... alarming facts are highlighted in this investigative article. In particular, ...
    Breaking Medicine News(10 mins):Health News:Americans Still Making Unhealthy Choices: CDC 2Health News:Americans Still Making Unhealthy Choices: CDC 3Health News:Project Managers Organize Manufacturing Projects and Training with the New Steptracker Project Status Magnetic Whiteboards 2Health News:Registry questions superiority of bivalirudin over heparin 2Health News:PreDiabetes Centers to Appear at the Philadelphia Tour de Cure 2Health News:PreDiabetes Centers to Appear at the Philadelphia Tour de Cure 3Health News:Black American Obesity Examined In The Latest FinancesOnline.com Article 2Health News:Black American Obesity Examined In The Latest FinancesOnline.com Article 3
    ... Dr. Eric Olson, chairman of molecular biology at UT ... France,s prestigious Lefoulon-Delalande Foundation Grand Prize for his work ... The prize has an international reputation as the ... about $664,000 (500,000 euros) will be presented June 10 ...
    ... , LOUISVILLE, Colo., June 4 /PRNewswire/ -- ... 13 GHXcellence Awards for achievements in improving supply chain performance. ... a recognition ceremony in Nashville at the 9th Annual GHX ... focused on both the buy and sell side of the ...
    ... The Minneapolis-St. Paul office of Weber Shandwick has been ... the organization,s largest annual awareness campaign. The "Be The ... to reach a diverse audience of current and potential ... with leukemia and other life-threatening diseases, a marrow transplant ...
    ... to Reduce Administrative Costs in Healthcare and Streamlines Processes ... N.J., June 4 MD On-Line Inc ... core focus of converting paper submitting providers to electronic ... Corp. (MCC) of Bristol, CT. Both are EHNAC-accredited ...
    ... nursing homes with one in four residents carrying the bacteria, a ... Its authors say that the findings, which have been ... highlight the need for infection control strategies to be given a ... be the largest of its kind studying MRSA in private nursing ...
    ... Fitness and Nutrition Program from Fitness Expert Monique Hollowell ... often feel their bodies will never be the same ... a fit pregnancy, less painful birth and quick recovery ... and personal trainer, Monique Hollowell has created a fitness ...
    Cached Medicine News:Health News:UT Southwestern's Olson wins prestigious French award for heart research 2Health News:GHXcellence Awards Honor Healthcare Providers and Suppliers for Achievements in Supply Chain Performance 2Health News:GHXcellence Awards Honor Healthcare Providers and Suppliers for Achievements in Supply Chain Performance 3Health News:Weber Shandwick Chosen By National Marrow Donor Program(R) To Head Awareness Campaign 2Health News:Weber Shandwick Chosen By National Marrow Donor Program(R) To Head Awareness Campaign 3Health News:MD On-Line Inc. Acquires Medical Claim Corp. 2Health News:1 in 4 nursing home residents carry MRSA 2Health News:Keys to a Fit Pregnancy and Losing the Baby Weight 2Health News:Keys to a Fit Pregnancy and Losing the Baby Weight 3
    EnTrust family of ICDs provides a suite of features for total AT/AF co-morbidity management, including diagnostics to detect when your patient develops AT/AF, and both termination and intervention th...
    ... Medical is the world leader in ... used worldwide for permanent pacemaker and ... and port implantation, and for temporary ... St. Jude Medical Peel-Away introducers includes ...
    ... Stent System combines low-profile, high radial force, and ... wire compatible stent system provides 6F sheath / ... - 10.0 mm). Now, with longer stents available, ... stent lengths (28, 38, 56, 80 and 100 ...
    ... transseptal left heart catheterization occurs when the ... a sheath with an alternate curve while ... an exchange has required a repeat septal ... has overcome this problem with the unique ...
    Medicine Products: